Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...
24 KB (2,894 words) - 01:36, 26 August 2023
The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
24 KB (2,932 words) - 03:26, 14 June 2024
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
7 KB (654 words) - 21:00, 23 April 2024
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
30 KB (2,727 words) - 19:16, 6 April 2024
Interferons (IFNs, /ˌɪntərˈfɪərɒn/ IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several...
62 KB (7,065 words) - 05:17, 28 June 2024
Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and...
10 KB (793 words) - 20:09, 20 December 2023
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
Interferon alpha-n3 (Alferon-N) is a medication consisting of purified natural human interferon alpha proteins used for the treatment of genital warts...
3 KB (28 words) - 01:47, 2 December 2023
Peginterferon alfa-2a (redirect from Pegylated interferon-alpha-2a)
Pegylated interferon alfa-2a is in the alpha interferon family of medications. It is pegylated to protect the molecule from breakdown. Pegylated interferon alfa-2a...
11 KB (892 words) - 19:27, 17 March 2024
Sehgal PB (1985). "On the relationship between human interferon alpha 1 and beta 1 genes". J. Interferon Res. 5 (3): 521–6. doi:10.1089/jir.1985.5.521. PMID 2414376...
7 KB (857 words) - 15:36, 17 May 2024
feline interferon omega (RFeIFN-ω), sold under the brand name Virbagen Omega among others, is a recombinant version of a cat interferon alpha. It is used...
6 KB (454 words) - 05:59, 3 December 2023
Interferon alpha-1/13, also known as IFN-alpha-1/13, is a protein that in humans is encoded by the IFNA1 and IFNA13 genes. GRCh38: Ensembl release 89:...
9 KB (1,005 words) - 07:07, 23 June 2024
Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
56 KB (6,476 words) - 11:26, 29 July 2024
Interferon alfacon-1 is a recombinant synthetic type I interferon used for the treatment of hairy cell leukemia, malignant melanoma and AIDS-related Kaposi's...
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Peginterferon alfa-2b (redirect from Pegylated interferon-alpha-2b)
Subcutaneous injection is the preferred delivery method. Belonging to the alpha interferon family of medications, the molecule is PEGylated to prevent breakdown...
14 KB (1,253 words) - 06:00, 18 March 2024
Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of...
20 KB (2,608 words) - 08:06, 11 January 2024
IFNW1 (redirect from Interferon omega)
1016/S0888-7543(05)80238-1. PMID 1385305. "Entrez Gene: IFNW1 interferon, omega 1". Bekisz J, Schmeisser H, Hernandez J, et al. (2005). "Human interferons alpha, beta and...
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encodes IFN-γR1, which is the ligand-binding chain (alpha) of the heterodimeric gamma interferon receptor, which is found on macrophages. IFNGR2, encodes...
12 KB (1,390 words) - 22:37, 2 April 2024
Interferon alpha-10 is a protein that in humans is encoded by the IFNA10 gene. GRCh38: Ensembl release 89: ENSG00000186803 – Ensembl, May 2017 GRCm38:...
4 KB (481 words) - 13:56, 8 September 2023
IRF3 (redirect from Interferon regulatory factor-3)
the nucleus for the transcriptional activation of interferons alpha and beta, and further interferon-induced genes. IRF3 plays an important role in the...
12 KB (1,493 words) - 01:36, 11 December 2023
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene. The protein encoded by this gene is a type I membrane...
11 KB (1,344 words) - 22:19, 10 December 2023
Cell-mediated immunity (redirect from Type 1 immunity)
humans that the signature cytokines for these cells are interferon gamma and lymphotoxin alpha. The main cytokine for differentiation into TH1 cells is...
14 KB (1,381 words) - 03:19, 4 May 2024
Plasmacytoid dendritic cell (redirect from Interferon Producing Cells)
type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. They circulate in the blood...
14 KB (1,833 words) - 05:36, 27 December 2023
IRF7 (redirect from Interferon regulatory factor-7)
virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is...
11 KB (1,417 words) - 07:42, 7 July 2023
Interferon alpha-4 is a protein that in humans is encoded by the IFNA4 gene. GRCh38: Ensembl release 89: ENSG00000236637 – Ensembl, May 2017 GRCm38: Ensembl...
4 KB (524 words) - 18:53, 13 October 2022
receptor proteins. Members of this family include: The human interferon gamma receptor 1, which is a member of the hematopoietic cytokine receptor superfamily...
3 KB (313 words) - 20:28, 22 December 2020
List of A1 genes, proteins or receptors (redirect from Alpha 1 gene)
constant alpha 1 Importin alpha 1 Interferon, alpha 1 Interleukin 13 receptor, alpha 1 Karyopherin alpha 1 Laminin, alpha 1 Major histocompatibility complex...
5 KB (667 words) - 18:06, 14 March 2022
Interferon alpha-6 is a protein that in humans is encoded by the IFNA6 gene. GRCh38: Ensembl release 89: ENSG00000120235 – Ensembl, May 2017 GRCm38: Ensembl...
3 KB (394 words) - 18:53, 13 October 2022
Integrin alphaXbeta2 Interferome Interferon Interferon beta 1a Interferon beta 1b Interferon gamma Interferon type I Interferon type II Interferon type III...
13 KB (1,237 words) - 01:24, 15 January 2024
STAT1 (redirect from Signal transducer and activator of transcription 1)
Specifically STAT1 can be activated by several ligands such as Interferon alpha (IFNα), Interferon gamma (IFNγ), Epidermal Growth Factor (EGF), Platelet Derived...
31 KB (3,702 words) - 10:57, 15 July 2024