• Thumbnail for Interferon gamma receptor 2
    Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding...
    2 KB (245 words) - 00:15, 8 October 2023
  • Thumbnail for Interferon-gamma receptor
    The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
    8 KB (870 words) - 23:14, 28 May 2024
  • Thumbnail for Interferon gamma
    heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
    56 KB (6,476 words) - 06:27, 13 September 2024
  • Thumbnail for Interferon gamma receptor 1
    Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene....
    12 KB (1,390 words) - 22:37, 2 April 2024
  • Thumbnail for Interferon-alpha/beta receptor
    The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
    24 KB (2,617 words) - 19:43, 7 August 2022
  • interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
    6 KB (616 words) - 18:29, 7 June 2023
  • Thumbnail for Interferon
    Based on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs...
    62 KB (7,065 words) - 05:17, 28 June 2024
  • Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1)...
    10 KB (1,126 words) - 20:57, 24 June 2021
  • Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
    7 KB (662 words) - 22:43, 14 September 2024
  • complete deficiency in the interferon-gamma receptor have significant elevations in plasma concentrations of interferon-gamma, which can be measured by...
    14 KB (1,413 words) - 03:44, 11 October 2023
  • Thumbnail for IL-2 receptor
    IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γc, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.: 713 ...
    9 KB (934 words) - 17:14, 27 August 2024
  • Thumbnail for Interferon type I
    pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
    24 KB (2,932 words) - 03:26, 14 June 2024
  • Thumbnail for Peroxisome proliferator-activated receptor gamma
    proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1...
    19 KB (2,091 words) - 05:22, 13 July 2024
  • problems. Interleukin 12 receptor, beta 1 deficiency IL-12p40 deficiency Interferon gamma receptor 1 deficiency Interferon gamma receptor 2 deficiency Tyk2 deficiency...
    19 KB (1,836 words) - 09:52, 5 July 2024
  • Thumbnail for Toll-like receptor 4
    Nishikawa H, et al. (February 2003). "Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent...
    75 KB (9,082 words) - 22:17, 25 September 2024
  • Thumbnail for Interleukin 12
    the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural...
    14 KB (1,578 words) - 14:00, 26 February 2024
  • Thumbnail for Interleukin 18
    Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene. The protein encoded by...
    18 KB (2,082 words) - 08:54, 18 March 2024
  • Thumbnail for RIG-I
    RIG-I (category RIG-I-like receptors)
    gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response. RIG-I is an essential molecule...
    23 KB (2,831 words) - 16:57, 27 August 2024
  • Thumbnail for RAR-related orphan receptor gamma
    RAR-related orphan receptor gamma (RORγ) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. RORγ is a member of...
    21 KB (2,372 words) - 01:41, 15 December 2023
  • Thumbnail for Chromosome 21
    IFNAR1: encoding interferon alpha/beta receptor 1 IFNAR2: encoding interferon alpha/beta receptor 2 IFNGR2: encoding interferon gamma receptor 2 IL10RB: encoding...
    34 KB (3,087 words) - 13:30, 30 July 2024
  • Thumbnail for Tyrosine kinase 2
    cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling...
    25 KB (2,850 words) - 23:00, 12 November 2023
  • Thumbnail for Cell-mediated immunity
    chemokines CXCL9, CXCL10 and CXCL11 in response to interferon gamma. Additionally, interferon gamma secreted by these cells seems to be important in downregulating...
    14 KB (1,381 words) - 19:57, 18 August 2024
  • Thumbnail for Retinoic acid receptor gamma
    Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, group B, member 3) is a nuclear receptor encoded by the RARG...
    10 KB (1,208 words) - 06:34, 8 November 2023
  • Thumbnail for Interleukin-1 receptor antagonist
    (March 2023). "Tumour necrosis factor alpha, interleukin 1 beta and interferon gamma have detrimental effects on equine tenocytes that cannot be rescued...
    12 KB (1,323 words) - 14:55, 7 September 2024
  • Thumbnail for Interleukin 10
    signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins. Consequently, the functional receptor consists of four...
    40 KB (4,619 words) - 05:18, 22 August 2024
  • Thumbnail for Interferon alpha-1
    lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.[supplied by OMIM] The interferons (IFN)s are...
    24 KB (2,894 words) - 01:36, 26 August 2023
  • Thumbnail for Histamine H1 receptor
    (November 1999). "Histamine and histamine-receptor antagonists modify gene expression and biosynthesis of interferon gamma in peripheral human blood mononuclear...
    15 KB (1,740 words) - 16:17, 21 August 2024
  • hormone receptor is a receptor molecule that binds to a specific hormone. Hormone receptors are a wide family of proteins made up of receptors for thyroid...
    17 KB (2,005 words) - 23:01, 20 August 2024
  • Thumbnail for CXCL10
    C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein...
    10 KB (1,231 words) - 22:00, 8 March 2024
  • responses to some cytokines, such as interferon-gamma. JAK1 and JAK2 are involved in type II interferon (interferon-gamma) signalling, whereas JAK1 and TYK2...
    9 KB (974 words) - 14:46, 22 June 2024