Isoxazolines are a class of five-membered heterocyclic chemical compounds, containing one atom each of oxygen and nitrogen which are located adjacent to...
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Afoxolaner (category Isoxazolines)
Afoxolaner (INN) is an insecticide and acaricide that belongs to the isoxazoline chemical compound group. It acts as an antagonist at GABA-receptors (those...
14 KB (1,126 words) - 01:28, 16 June 2024
Fluralaner (category Isoxazolines)
Owners and Veterinarians about Potential Adverse Events Associated with Isoxazoline Flea and Tick Products". FDA. Archived from the original on 22 May 2021...
15 KB (939 words) - 08:00, 26 August 2024
heartworm disease Dirofilaria immitis. It contains esafoxolaner, an aryl isoxazoline; eprinomectin, an avermectin anthelmintic; and praziquantel, a pyrazinoisoquinoline...
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intermediate host (the flea) before the infective metacestode can develop. Some isoxazoline products are registered to prevent flea tapeworm infestations using this...
13 KB (1,531 words) - 21:20, 1 November 2024
refer to: Acrylamide (repeating unit in polyacrylamide) 2-Azetidinone Isoxazoline Lactonitrile Oxazoline This set index page lists chemical structure articles...
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Gobbi, Marco; De Micheli, Carlo (2012). "A novel spirocyclic tropanyl-Δ2-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters...
111 KB (5,561 words) - 10:04, 1 November 2024
Amici M, De Micheli C, Klotz KN (April 1998). "Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic...
1 KB (57 words) - 11:34, 21 October 2024
M, Riganti L, et al. (December 2010). "Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal...
8 KB (703 words) - 06:13, 9 February 2024
G, Matera C, Pomè DY, et al. (June 2010). "Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity...
13 KB (1,257 words) - 05:23, 22 November 2024
Nitrogen + Oxygen Oxazolidine Isoxazolidine Oxazole (Oxazoline) Isoxazole (Isoxazoline) Nitrogen + Sulfur Thiazolidine Isothiazolidine Thiazole (Thiazoline)...
20 KB (1,019 words) - 22:20, 25 October 2024
Fullerene Complexes [[Ph3P]2Pt]6(η2-C60) Ru3(CO)9(C60) Platinum complex of isoxazoline-modified fullerene. C60 forms stable complexes of the type M(C60)(diphosphine)(CO)3...
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the combination of a nitrone with an alkene or alkyne to generate an isoxazoline or isoxazolidine via a (3+2) cycloaddition process. This reaction is...
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function as chelating ligands. Isoxazolidine, isomeric with oxazolidine. Isoxazoline, isomeric with oxazoline. Oxazolidinedione, which has two in-cycle keto...
10 KB (936 words) - 21:10, 16 November 2023
G, Grazioso G, Matera C, Pomè DY, et al. (2010). "Novel tricyclic Δ2-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: Synthesis and binding affinity...
115 KB (7,883 words) - 19:36, 27 October 2024
strain-promoted alkyne-nitrone cycloadditions (SPANC) to yield N-alkylated isoxazolines. Because this reaction is metal-free and proceeds with fast kinetics...
48 KB (5,450 words) - 01:17, 21 November 2024
Oxathiapiprolin (category Isoxazolines)
Oxathiapiprolin (trade names Orondis, Zorvec, and Segovis) is a fungicide. In the United States, the Environmental Protection Agency has approved it for...
4 KB (214 words) - 17:57, 28 October 2022
M, Gobbi M, et al. (November 2012). "A novel spirocyclic tropanyl-Δ²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters...
31 KB (3,438 words) - 05:47, 22 August 2024
Sarolaner (category Isoxazolines)
"Discovery of sarolaner: A novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs" (PDF). Veterinary Parasitology. 222: 3–11...
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the unsaturated analogues of oxazolidines, and they are isomeric with isoxazolines, where the N and O are directly bonded. Two isomers of oxazoline are...
17 KB (1,742 words) - 02:58, 5 November 2024
used include doramectin and milbemycin. Recent results suggest that the isoxazolines afoxolaner and fluralaner, given orally, are effective in treating dogs...
13 KB (1,498 words) - 01:44, 12 September 2024
pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine...
26 KB (2,690 words) - 18:07, 20 October 2024
meta-diamide GABA-gated Cl− channel allosteric modulator. This - along with isoxazolines providing the same MoA, so far only fluxametamide - constitute the new...
5 KB (299 words) - 18:49, 10 April 2024
Exzolt was introduced in the EU in 2017, it contains fluralaner, an isoxazoline, and is highly effective against D. gallinae, included those resistant...
22 KB (2,283 words) - 20:41, 17 October 2024
an alkene yields the cyclic isoxazoline product, whereas the reaction with an alkyne yields the isoxazole. Both isoxazolines and isoxazoles can be cleaved...
65 KB (6,396 words) - 21:04, 1 August 2024
Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation". ChemMedChem...
10 KB (973 words) - 14:48, 11 September 2024
-4-methoxy-2-pentanones: Synthesis via Corresponding 3-Hydroxy Ketones Generated from 2-Isoxazolines". Journal of Organic Chemistry. 61 (24): 8604–8609. doi:10.1021/jo960887a...
5 KB (481 words) - 23:40, 9 November 2024
Lotilaner (category Isoxazolines)
Lotilaner, sold under the brand name Xdemvy, is an ectoparasiticide (anti-parasitic) medication used for the treatment of blepharitis (inflammation of...
12 KB (690 words) - 02:26, 29 August 2024
M, Riganti L, et al. (December 2010). "Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal...
26 KB (2,694 words) - 12:18, 31 October 2024
ATCvet code QP53 (section QP53BE Isoxazolines)
ATCvet code QP53 Ectoparasiticides, including insecticides and repellents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification...
4 KB (332 words) - 03:52, 10 October 2023