• Kallikreins are a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. In humans, plasma kallikrein (encoded by KLKB1...
    11 KB (1,172 words) - 05:55, 19 September 2024
  • The kinin–kallikrein system or simply kinin system is a poorly understood hormonal system with limited available research. It consists of blood proteins...
    7 KB (855 words) - 03:08, 24 June 2024
  • Term ''kallikrein 7 may refer to: Stratum corneum chymotryptic enzyme, an enzyme class KLK7, a serine protease that in humans is encoded by the KLK7 gene...
    184 bytes (58 words) - 01:11, 29 December 2019
  • Thumbnail for Prostate-specific antigen
    gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase...
    50 KB (5,683 words) - 05:06, 17 August 2024
  • Thumbnail for Kallikrein-5
    Kallikrein-5, formerly known as stratum corneum tryptic enzyme (SCTE), is a serine protease expressed in the epidermis. In humans it is encoded by the...
    9 KB (1,115 words) - 21:12, 27 March 2024
  • Urinary kallikrein may refer to: Plasma kallikrein, an enzyme Renal tissue kallikrein, an enzyme This set index page lists enzyme articles associated...
    426 bytes (47 words) - 20:07, 4 February 2015
  • tissue kallikrein (EC 3.4.21.35, glandular kallikrein, pancreatic kallikrein, submandibular kallikrein, submaxillary kallikrein, kidney kallikrein, urinary...
    8 KB (857 words) - 03:47, 22 June 2024
  • Thumbnail for Plasma kallikrein
    Plasma kallikrein (EC 3.4.21.34) is an enzyme that catalyses the following chemical reaction: Selective cleavage of some Arg- and Lys- bonds, including...
    13 KB (1,616 words) - 21:27, 8 April 2024
  • Thumbnail for KLK6
    KLK6 (redirect from Kallikrein-6)
    Kallikrein-6 is a protein that in humans is encoded by the KLK6 gene. Kallikrein-6 is also referred to as neurosin, protease M, hK6, or zyme. It is a 223...
    16 KB (1,866 words) - 18:53, 12 October 2024
  • Thumbnail for KLK2
    KLK2 (redirect from Kallikrein-2)
    Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. GRCh38: Ensembl release 89:...
    10 KB (1,089 words) - 18:53, 12 October 2024
  • Recombinant human tissue kallikrein-1, also known as DM199, is an experimental drug that acts on the kallikrein-kinin system and is developed for diabetes...
    3 KB (237 words) - 11:39, 4 January 2024
  • Kallikrein 13 (EC 3.4.21.119, KLK13, kallikrein mK13, mGK-13, mK13, mKLK13, prorenin converting enzyme 1, PRECE-1, prorenin-converting enzyme, PRECE,...
    2 KB (270 words) - 14:38, 26 August 2023
  • Thumbnail for Contact activation system
    proteases and HK is a non-enzymatic co-factor. The CAS can activate the kinin–kallikrein system and blood coagulation through its ability to activate multiple...
    12 KB (1,456 words) - 06:25, 22 May 2024
  • Thumbnail for Hereditary angioedema
    prevent HAE attacks by inactivating the kallikrein B1 (KLKB1) gene, which encodes for prekallikrein, the kallikrein precursor protein. "Hereditary angioedema"...
    39 KB (4,188 words) - 06:09, 24 September 2024
  • Thumbnail for Desquamation
    granulosum produce corneodesmosome-degrading kallikrein family members, especially KLK1, KLK5, and KLK7. Kallikreins are serine proteases. They are packaged...
    9 KB (878 words) - 21:05, 24 July 2024
  • Thumbnail for KLK14
    KLK14 (redirect from Kallikrein-14)
    Kallikrein-14 is a protein that in humans is encoded by the KLK14 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions...
    10 KB (1,185 words) - 18:53, 12 October 2024
  • Thumbnail for Saliva
    is not activated until entering the acidic environment of the stomach Kallikrein, an enzyme that proteolytically cleaves high-molecular-weight kininogen...
    25 KB (2,799 words) - 15:49, 3 September 2024
  • kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein....
    6 KB (517 words) - 20:11, 20 December 2023
  • Thumbnail for KLK4
    KLK4 (redirect from Kallikrein-4)
    Kallikrein-related peptidase 4 is a protein which in humans is encoded by the KLK4 gene. Kallikreins are a subgroup of serine proteases having diverse...
    11 KB (1,328 words) - 04:52, 24 December 2023
  • Thumbnail for Sebetralstat
    evaluated for the treatment of hereditary angioedema. It is a plasma kallikrein inhibitor. "Sebetralstat - KalVista Pharmaceuticals". AdisInsight. Springer...
    3 KB (93 words) - 20:27, 10 September 2024
  • Thumbnail for Angioedema
    C1-esterase (aka: C1-inhibitor or C1INH), and continuous production of kallikrein, another process inhibited by C1INH. This serine protease inhibitor (serpin)...
    26 KB (3,008 words) - 06:59, 14 September 2024
  • Kallikrein 8 (EC 3.4.21.118, KLK8, PRSS19, human kallikrein 8, hK8, mK8, ovasin, tumor-associated differentially expressed gene 14, TADG-14, NP, neuropsin)...
    3 KB (281 words) - 14:38, 26 August 2023
  • Kinin (category Kinin–kallikrein system)
    kininogens by the process of kallikreins. Kallikreins activate kinins when stimulated. It is a component of the kinin-kallikrein system. Their precursors...
    7 KB (820 words) - 12:07, 24 December 2023
  • Thumbnail for Stratum corneum
    to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating...
    10 KB (1,119 words) - 17:24, 4 July 2024
  • Thumbnail for Alpha-2-Macroglobulin
    It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. α2-macroglobulin...
    14 KB (1,631 words) - 05:36, 8 March 2024
  • contribute to the syndrome include serotonin, histamine, tachykinins, kallikrein, and prostaglandins with the greatest contribution appearing to be from...
    17 KB (1,812 words) - 00:11, 31 August 2024
  • is a human monoclonal antibody (class IgG1 kappa) that targets plasma kallikrein (pKal) in order to promote prevention of angioedema in people with hereditary...
    18 KB (1,305 words) - 05:07, 15 September 2024
  • reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme. This...
    2 KB (172 words) - 15:48, 26 August 2023
  • Thumbnail for Digestive enzyme
    start their digestion in the mouth (however, trace amounts of the enzyme kallikrein, which catabolises certain protein, is found in saliva in the mouth)....
    18 KB (2,239 words) - 09:27, 1 August 2024
  • the kallikrein-kinin system. In: The Kinin System. Academic Press, San Diego, CA, 1997. Beraldo WT, Siqueira G, Heneine IF. Kallikrein and kallikrein inhibitor...
    4 KB (335 words) - 07:53, 26 February 2024