Homolog 3 (MSH3) is a human homologue of the bacterial mismatch repair protein MutS that participates in the mismatch repair (MMR) system. MSH3 typically...
17 KB (2,080 words) - 15:35, 9 January 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–08. doi:10.1093/carcin/bgl079. PMC 2612936...
185 KB (20,011 words) - 15:21, 24 August 2024
to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many different...
35 KB (4,237 words) - 07:05, 26 August 2024
gland, and related to skin pigmentation DNA mismatch repair genes: MSH2 MSH3 MSH4 MSH5 MSH6 Multiple system atrophy Mycothiol, an unusual thiol that is...
1 KB (153 words) - 01:59, 5 September 2023
eukaryotes, MutS homologs form two major heterodimers: Msh2/Msh6 (MutSα) and Msh2/Msh3 (MutSβ). The MutSα pathway is involved primarily in base substitution and...
35 KB (4,179 words) - 12:12, 19 July 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936...
51 KB (5,896 words) - 02:30, 20 August 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–08. doi:10.1093/carcin/bgl079. PMC 2612936...
129 KB (15,900 words) - 06:12, 13 August 2024
genetic events, hypermutated tumors display mutated forms of ACVR2A, TGFBR2, MSH3, MSH6, SLC9A9, TCF7L2, and BRAF. The common theme among these genes, across...
145 KB (15,793 words) - 15:10, 19 August 2024
syndrome Several genes have been associated with polyposis, such as GREM1, MSH3, MLH3, NTHL1, RNF43 and RPS20. Familial adenomatous polyposis (FAP) is a...
30 KB (2,858 words) - 07:50, 6 April 2024
alpha-helices, which is similar to the structure of tRNA endonuclease. Yeast MSH3, bacterial proteins involved in DNA mismatch repair, and the predicted protein...
8 KB (900 words) - 00:35, 16 December 2020
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079...
30 KB (3,246 words) - 02:33, 23 May 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079...
23 KB (2,829 words) - 04:04, 16 January 2024
"Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease". J. Biol. Chem. 289 (9): 5664–73. doi:10.1074/jbc...
15 KB (1,706 words) - 11:18, 21 May 2024
endonuclease 1 GADD45A GADD45G HDAC1 HUS1 ING1 KCTD13 KIAA0101 Ku70 Ku80 MCL1 MSH3 MSH6 MUTYH P21 POLD2 POLD3 POLDIP2 POLH POLL RFC1 RFC2 RFC3 RFC4 RFC5 Ubiquitin...
53 KB (6,158 words) - 18:54, 23 April 2024
Telangana border via MSH 264) Amravati. Wardha MH SH 244 (From Yavatmal via MSH3) – Pulgaon – Arvi – Talegaon (on NH6) – Ashti – Warud to Multai (MP) Wardha...
32 KB (85 words) - 19:56, 25 August 2024
ESR1 FANCA FANCD2 FHL2 H2AFX JUNB JunD LMO4 MAP3K3 MED17 MED21 MRE11A MSH2 MSH3 MSH6 Myc NBN NMI NPM1 NCOA2 NUFIP1 P53 PALB2 POLR2A PPP1CA Rad50 RAD51 RBBP4...
121 KB (13,581 words) - 14:59, 8 August 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936...
115 KB (13,937 words) - 12:31, 12 July 2024
HGNC:7321 O60682 9908 MSGN1 HGNC:14907 A6NI15 9909 MSH2 HGNC:7325 P43246 9910 MSH3 HGNC:7326 P20585 9911 MSH4 HGNC:7327 O15457 9912 MSH5 HGNC:7328 O43196 9913...
277 KB (17 words) - 15:46, 9 May 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936...
61 KB (6,663 words) - 21:44, 7 August 2024
The seven DNA mismatch repair proteins in humans are MLH1, MLH3, MSH2, MSH3, MSH6, PMS1 and PMS2. In addition, there are Exo1-dependent and Exo1-independent...
28 KB (3,414 words) - 13:04, 19 July 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936...
25 KB (2,804 words) - 06:09, 10 June 2024
"Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease". J. Biol. Chem. 289 (9): 5664–73. doi:10.1074/jbc...
34 KB (3,885 words) - 08:06, 6 April 2024
performed in DT40 cells upon removal of MSH3, an essential protein in MMR. The resulting microDNA from the DT40 MSH3-/- cell line had a higher enrichment...
12 KB (1,452 words) - 22:25, 28 January 2022
The sanctuary is closed on Mondays. Traveling on the Wardha-Nagpur road MSH3, one must turn north at Seloo for Hingi and then to the visitor center at...
18 KB (1,774 words) - 09:17, 26 March 2024
although hMSH2 itself can function as a homomultimer or as a heterodimer with hMSH3. Mismatches commonly occur as a result of DNA replication errors, genetic...
23 KB (2,942 words) - 20:15, 5 April 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079...
111 KB (12,533 words) - 04:42, 11 August 2024
instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936...
38 KB (4,560 words) - 18:55, 4 August 2024
intermediate can avoid mismatch repair due to its affinity for the MSH-2-MSH3 complex, which stabilizes the hairpin instead of repairing it. In non-dividing...
61 KB (7,973 words) - 04:54, 27 May 2024
important new genetic modifier of disease progression in Huntington’s disease (MSH3, a mismatch repair protein), which has opened up new avenues of research...
39 KB (3,619 words) - 12:55, 15 August 2024
of genetic mutations. Deficiency of DNA repair proteins PMS2, MLH1, MSH2, MSH3, MSH6 or BRCA2 can cause up to 100-fold increases in mutation frequency Epigenetic...
87 KB (9,928 words) - 12:18, 13 August 2024