• Thumbnail for Medulloblastoma
    Medulloblastoma is a common type of primary brain cancer in children. It originates in the part of the brain that is towards the back and the bottom,...
    36 KB (3,455 words) - 22:51, 26 April 2024
  • Thumbnail for Blastoma
    precursor cells, often called blasts. Examples are nephroblastoma, medulloblastoma, and retinoblastoma. The suffix -blastoma is used to imply a tumor...
    13 KB (1,699 words) - 18:30, 25 February 2024
  • wrestling-inspired nicknames "Stone Crusher" and "The Crusher". He developed medulloblastoma in September 2009, when he was three years old. After his diagnosis...
    15 KB (1,493 words) - 00:43, 15 August 2024
  • Thumbnail for Tumor suppressor gene
    rule are those that exhibit haploinsufficiency, including PTCH in medulloblastoma and NF1 in neurofibroma. Another example is p27, a cell-cycle inhibitor...
    30 KB (3,409 words) - 03:56, 11 June 2024
  • Thumbnail for Brain tumor
    as glioblastomas. In children, the most common type is a malignant medulloblastoma. Diagnosis is usually by medical examination along with computed tomography...
    93 KB (10,308 words) - 16:32, 12 October 2024
  • Thumbnail for WWE
    (October 17, 2005 – April 25, 2014) who had died two months earlier from medulloblastoma, a rare tumor that affects the brain and spinal cord. Beginning in...
    223 KB (22,499 words) - 10:15, 14 October 2024
  • a marked increase in disease-free survival rates for patients with medulloblastoma - again, up to around 85%. This application of cisplatin was developed...
    8 KB (827 words) - 17:01, 6 April 2024
  • Thumbnail for CD46
    ligand. Established medulloblastoma (a malignant brain tumor common in childhood) specimens express CD46, and that medulloblastoma specimens removed from...
    10 KB (1,159 words) - 07:15, 15 October 2024
  • Thumbnail for Protein BTG2
    prevents the growth of medulloblastoma lesions in a Shh-type mouse model of medulloblastoma. Thus, CXCL3 is a target for medulloblastoma therapy. BTG2 has...
    26 KB (3,182 words) - 08:36, 6 May 2024
  • Thumbnail for Atypical teratoid rhabdoid tumor
    MRT have a worse prognosis than medulloblastoma and are resistant to the standard treatment protocols for medulloblastoma.[citation needed] By 1995, AT/RT...
    54 KB (6,325 words) - 15:47, 4 August 2024
  • Thumbnail for Vismodegib
    small-cell lung cancer, advanced stomach cancer, pancreatic cancer, medulloblastoma and chondrosarcoma as of June 2011[update]. The drug was developed...
    7 KB (483 words) - 19:42, 20 December 2023
  • DAOY is a widely used human medulloblastoma cell line. It has epithelial morphology and was obtained from a 4-year-old Caucasian boy in 1985. It can be...
    3 KB (238 words) - 04:18, 24 June 2023
  • g. neuroblastoma, retinoblastoma, nephroblastoma, hepatoblastoma, medulloblastoma, etc.) than in older adults. Cancers are usually named using -carcinoma...
    12 KB (1,130 words) - 10:14, 4 October 2024
  • Thumbnail for Cerebellum
    activate Sonic hedgehog signaling predispose to cancer of the cerebellum (medulloblastoma) in humans with Gorlin Syndrome and in genetically engineered mouse...
    95 KB (11,629 words) - 07:31, 20 September 2024
  • Thumbnail for Cisplatin
    childhood medulloblastoma. The new protocol that he developed led to a marked increase in disease-free survival rates for patients with medulloblastoma, up...
    39 KB (3,864 words) - 22:43, 20 September 2024
  • Thumbnail for Metastasis
    types in addition to adenocarcinoma. Metastases of breast cancer, medulloblastoma and prostate cancer all had similar expression patterns of these...
    42 KB (5,025 words) - 08:41, 9 October 2024
  • are available and they are instead graded. Embryonal CNS tumors like medulloblastoma are staged following a classification developed by Chang et al. Breast...
    18 KB (1,832 words) - 15:57, 25 September 2024
  • Thumbnail for Nevoid basal-cell carcinoma syndrome
    be translocated to the nucleus. SUFU mutations are associated with medulloblastoma, a diagnostic criteria for NBCCS. Up to 70% of people with NBCCS inherit...
    15 KB (1,730 words) - 17:39, 22 April 2024
  • Thumbnail for Nervous tissue
    multiforme), Dysembryoplastic neuroepithelial tumour, Oligodendroglioma, Medulloblastoma, Primitive neuroectodermal tumor Neuroepitheliomatous tumors Ganglioneuroma...
    13 KB (1,380 words) - 09:19, 23 August 2024
  • including colorectal carcinoma, lung cancer, and medulloblastoma. In completely resected medulloblastoma, 5-year survival rate is 85% if adjuvant chemotherapy...
    40 KB (4,808 words) - 04:21, 1 July 2024
  • lab currently studies the regulation of BTIC signaling pathways in medulloblastomas (MB), glioblastomas (GBM), and brain metastases (BM). Singh's lab found...
    13 KB (1,514 words) - 13:53, 2 October 2024
  • Aneurysmal bone cyst Ewing's sarcoma Metastases from brain stem tumors (medulloblastoma, ependymoma, high-grade astrocytoma) Urinary incontinence Fecal incontinence...
    1 KB (109 words) - 09:36, 23 July 2024
  • brain-specific snRNA that targets the serotonin-2C receptor mRNA. Medulloblastoma – The U1 snRNA is mutated in a subset of these brain tumors, and leads...
    17 KB (2,325 words) - 18:40, 12 September 2024
  • Thumbnail for Cyclin-dependent kinase 6
    function. The gene is overexpressed in cancers like lymphoma, leukemia, medulloblastoma and melanoma associated with chromosomal rearrangements. The CDK6 protein...
    35 KB (4,042 words) - 05:00, 1 April 2024
  • Thumbnail for Michael Froman
    daughter, Sarah. His older son, Jacob, died in 2009 at age ten from a medulloblastoma, a rare form of pediatric brain cancer. "Michael Froman '91 joins White...
    18 KB (1,581 words) - 02:40, 28 September 2024
  • Thumbnail for Cerebellar granule cell
    activate Sonic hedgehog signaling predispose to cancer of the cerebellum (medulloblastoma) in humans with Gorlin syndrome and in genetically engineered mouse...
    9 KB (1,037 words) - 03:11, 22 June 2024
  • Thumbnail for Ependymoma
    malignant ependymoma and the ependymoblastoma, are treated similarly to medulloblastoma but the prognosis is much less favorable. Malignant ependymomas may...
    11 KB (1,112 words) - 00:40, 17 September 2024
  • Thumbnail for Nystagmus
    follows: Aniridia Benign paroxysmal positional vertigo Brain tumors (medulloblastoma, astrocytoma, or other tumors in the posterior fossa.) Canavan disease...
    37 KB (4,092 words) - 14:48, 9 October 2024
  • Thumbnail for Lumbar puncture
    presence of malignant cells in the CSF, as in carcinomatous meningitis or medulloblastoma. CSF containing less than 10 red blood cells (RBCs)/mm3 constitutes...
    47 KB (5,382 words) - 18:28, 4 October 2024
  • Thumbnail for CXCL3
    prevents the growth of medulloblastoma lesions in a Shh-type mouse model of medulloblastoma. Thus, CXCL3 is a target for medulloblastoma therapy. Cxcl3 is...
    4 KB (505 words) - 03:27, 28 October 2022