• Thumbnail for Metabotropic glutamate receptor 2
    Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that...
    22 KB (2,647 words) - 08:11, 10 March 2024
  • Thumbnail for Metabotropic glutamate receptor
    The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members...
    34 KB (3,629 words) - 17:37, 18 March 2024
  • Thumbnail for Metabotropic glutamate receptor 4
    Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of...
    16 KB (1,707 words) - 04:10, 2 December 2024
  • Thumbnail for Metabotropic glutamate receptor 8
    Metabotropic glutamate receptor 8 is a protein that in humans is encoded by the GRM8 gene. L-glutamate is the major excitatory neurotransmitter in the...
    6 KB (708 words) - 16:57, 28 November 2023
  • Thumbnail for Metabotropic glutamate receptor 7
    Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene. L-glutamate is the major excitatory neurotransmitter in the...
    12 KB (1,359 words) - 23:10, 4 April 2024
  • Thumbnail for Metabotropic glutamate receptor 6
    Glutamate receptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene. L-glutamate is the major excitatory...
    7 KB (868 words) - 09:00, 18 August 2023
  • Thumbnail for Metabotropic glutamate receptor 1
    The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein. L-Glutamate...
    22 KB (2,342 words) - 22:25, 20 September 2024
  • Thumbnail for Metabotropic glutamate receptor 3
    Metabotropic glutamate receptor 3 (mGluR3) is an inhibitory Gi/G0-coupled G-protein coupled receptor (GPCR) generally localized to presynaptic sites of...
    28 KB (3,074 words) - 08:11, 10 March 2024
  • Thumbnail for Metabotropic glutamate receptor 5
    Metabotropic glutamate receptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons....
    28 KB (3,032 words) - 17:40, 2 October 2024
  • Thumbnail for Glutamate receptor
    Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base...
    63 KB (6,876 words) - 07:52, 2 November 2024
  • A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
    6 KB (625 words) - 00:59, 6 June 2024
  • Thumbnail for Glutamate (neurotransmitter)
    Biochemical receptors for glutamate fall into three major classes, known as AMPA receptors, NMDA receptors, and metabotropic glutamate receptors. A fourth...
    20 KB (2,177 words) - 10:19, 11 December 2024
  • Thumbnail for Glutamic acid
    Glutamic acid (redirect from Glutamate)
    and metabotropic (G-protein coupled) receptors. In the opposing postsynaptic cell, glutamate receptors, such as the NMDA receptor or the AMPA receptor, bind...
    35 KB (3,235 words) - 06:08, 1 December 2024
  • Thumbnail for Neurotransmitter receptor
    message (i.e. metabotropic receptors do not have channels). There are several kinds of metabotropic receptors, including G protein-coupled receptors. Ionotropic...
    16 KB (1,590 words) - 11:48, 27 December 2024
  • Thumbnail for Glutamate flavoring
    N-methyl-D-aspartate (NMDA) type glutamate ion channel receptor; the second posits that the taste is transduced by a metabotropic type glutamate receptor (taste-mGluR4)...
    37 KB (4,017 words) - 00:36, 5 January 2025
  • Thumbnail for Kainate receptor
    Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate. They were first identified...
    11 KB (1,263 words) - 21:34, 11 June 2024
  • Thumbnail for Ionotropic glutamate receptor
    Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate. They mediate the majority...
    5 KB (433 words) - 06:16, 15 October 2023
  • Thumbnail for NMDA receptor
    receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...
    107 KB (12,058 words) - 11:59, 2 November 2024
  • Thumbnail for Ibotenic acid
    Ibotenic acid (category AMPA receptor agonists)
    mGluR3) metabotropic glutamate receptors. It is inactive at group III mGluRs. Ibotenic acid also acts as a weak agonist of the AMPA and kainate receptors. In...
    16 KB (1,473 words) - 03:44, 14 December 2024
  • Thumbnail for AMPA receptor
    acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate (iGluR) and predominantly...
    60 KB (7,024 words) - 22:23, 19 October 2024
  • Thumbnail for LY-341495
    LY-341495 (category MGlu2 receptor antagonists)
    potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3). It is used in scientific research in several different...
    11 KB (1,011 words) - 19:32, 20 December 2023
  • GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
    16 KB (1,564 words) - 20:19, 25 March 2024
  • Thumbnail for Kainic acid
    classifications of glutamate receptors: NMDA receptors, AMPA receptors, kainate receptors, and the metabotropic glutamate receptors. Kainic acid is an...
    11 KB (1,117 words) - 10:58, 18 October 2023
  • Thumbnail for Glutathione
    is synthesized from L-glutamate and L-cysteine. This conversion requires the enzyme glutamate–cysteine ligase (GCL, glutamate cysteine synthase). This...
    26 KB (2,668 words) - 22:10, 28 December 2024
  • Thumbnail for N-Acetylaspartylglutamic acid
    space by enzymatic activity. NAAG activates a specific receptor, the metabotropic glutamate receptor type 3. It is synthesized enzymatically from its two...
    13 KB (1,482 words) - 21:23, 19 August 2024
  • amino acid receptor agonist, or glutamate receptor agonist, is a chemical substance which agonizes one or more of the glutamate receptors. Examples include:...
    775 bytes (73 words) - 20:27, 27 November 2021
  • Excitatory amino acid receptor ligands are ligands of excitatory amino acid receptors (EAARs), also known as glutamate receptors. They include excitatory...
    991 bytes (85 words) - 05:39, 22 March 2024
  • means "related to glutamate". A glutamatergic agent (or drug) is a chemical that directly modulates the excitatory amino acid (glutamate/aspartate) system...
    983 bytes (63 words) - 09:23, 23 May 2023
  • Thumbnail for GABA receptor
    receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. It has long been recognized that, for neurons that...
    35 KB (3,892 words) - 05:20, 16 May 2024
  • Thumbnail for GRN-529
    GRN-529 (category Glutamate receptor negative allosteric modulators)
    developed by Wyeth as a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). A study conducted by Pfizer found that GRN-529...
    4 KB (214 words) - 20:13, 20 December 2023