• Thumbnail for MicroRNA
    MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are...
    146 KB (16,588 words) - 05:54, 3 June 2024
  • sequence microRNAs, also called miRNAs. miRNA-seq differs from other forms of RNA-seq in that input material is often enriched for small RNAs. miRNA-seq allows...
    49 KB (5,200 words) - 07:39, 12 December 2023
  • Thumbnail for MicroRNA biosensors
    MicroRNA (miRNA) biosensors are analytical devices that involve interactions between the target miRNA strands and recognition element on a detection platform...
    63 KB (7,155 words) - 08:01, 6 June 2024
  • Thumbnail for Messenger RNA
    RNA viruses. MicroRNAs (miRNAs) are small RNAs that typically are partially complementary to sequences in metazoan messenger RNAs. Binding of a miRNA...
    49 KB (5,922 words) - 00:21, 9 May 2024
  • Thumbnail for RNA interference
    ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
    141 KB (15,447 words) - 07:45, 10 June 2024
  • levels. Using single-stranded RNA (ssRNA) fragments, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA), the complex functions as...
    36 KB (3,836 words) - 14:30, 19 April 2024
  • Thumbnail for Non-coding RNA
    micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in...
    67 KB (7,214 words) - 06:02, 26 February 2024
  • multiple miRNA targets alter the number of unbound miRNAs and lead to observable changes in miRNA activity - i.e., the abundance of other miRNA targets...
    25 KB (3,214 words) - 11:33, 22 February 2024
  • interfering RNA (siRNA) and micro RNA (miRNA) to prevent mRNA translation and/or degrade mRNA. However, RNA aptamers are short, single stranded RNA molecules...
    77 KB (8,886 words) - 09:03, 10 June 2024
  • Thumbnail for Gene expression
    nucleotidyl transferase. In the case of micro RNA (miRNA), miRNAs are first transcribed as primary transcripts or pri-miRNA with a cap and poly-A tail and processed...
    81 KB (9,242 words) - 21:24, 22 May 2024
  • example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the...
    47 KB (5,479 words) - 09:28, 10 June 2024
  • Thumbnail for Atherosclerosis
    aorta. MicroRNAs (miRNAs) have complementary sequences in the 3' UTR and 5' UTR of target mRNAs of protein-coding genes, and cause mRNA cleavage or repression...
    99 KB (11,048 words) - 01:51, 21 May 2024
  • Thumbnail for Small interfering RNA
    typically 20–24 (normally 21) base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway. It interferes with the expression...
    55 KB (6,760 words) - 11:46, 28 April 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    64 KB (7,522 words) - 14:14, 6 June 2024
  • Thumbnail for Circular RNA
    targets miR-7 (hence the name CiRS-7 – Circular RNA Sponge for miR-7). It has over 60 miR-7 binding sites, far more than any known linear miRNA sponge...
    55 KB (6,557 words) - 15:18, 12 May 2024
  • Thumbnail for Serial analysis of gene expression
    Those may then be sequenced to identify the miRNA present, as well as analysing expression levels of a given miRNA by counting the number of times it is present...
    17 KB (2,127 words) - 11:27, 13 August 2023
  • of miRNA activity begins with the synthesis of pri-miRNA in the nucleus by RNA polymerase II which is then converted into pre-miRNA. This pre-miRNA exits...
    59 KB (7,765 words) - 06:48, 29 April 2024
  • Thumbnail for Dicer
    Dicer (category RNA interference)
    double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively...
    25 KB (3,276 words) - 23:57, 22 May 2024
  • Thumbnail for Fluorescence in situ hybridization
    identification. FISH can also be used to detect and localize specific RNA targets (mRNA, lncRNA and miRNA)[citation needed] in cells, circulating tumor cells, and...
    40 KB (4,617 words) - 07:25, 2 May 2024
  • Thumbnail for RNA-Seq
    mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq...
    101 KB (11,023 words) - 15:35, 29 May 2024
  • Oncomir (category RNA)
    is a microRNA (miRNA) that is associated with cancer. MicroRNAs are short RNA molecules about 22 nucleotides in length. Essentially, miRNAs specifically...
    19 KB (1,970 words) - 11:20, 22 February 2024
  • Thumbnail for Complementarity (molecular biology)
    that circulating miRNA may be utilized as novel biomarkers, hence show promising evidence to be utilized in disease diagnostics. MiRNAs are formed from...
    23 KB (2,586 words) - 20:09, 27 March 2024
  • The C19MC miRNA cluster is a microRNA cluster consisting of 46 genes. These 46 genes encode 59 mature miRNAs. The C19MC miRNA cluster is only found in...
    2 KB (200 words) - 00:18, 28 September 2022
  • which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing to...
    24 KB (2,664 words) - 18:03, 29 April 2024
  • municipality in Slovenia Mount Mirna, a hill in Slovenia Mirna (name), a female name microRNA, abbreviated as miRNA USS Mirna (SP-1214), a United States Navy...
    738 bytes (144 words) - 10:51, 7 July 2022
  • microRNA (miRNA) function in cells for desired responses. miRNA are complementary sequences (≈22 bp) to mRNA that are involved in the cleavage of RNA or...
    26 KB (3,342 words) - 03:06, 1 December 2023
  • ncRNAs function by binding to other RNAs. For example, miRNAs regulate protein coding gene expression by binding to 3' UTRs, small nucleolar RNAs guide...
    152 KB (8,423 words) - 21:37, 26 April 2024
  • Thumbnail for Epigenetics
    far, in 2013, about 2000 miRNAs have been discovered in humans and these can be found online in a miRNA database. Each miRNA expressed in a cell may target...
    161 KB (18,434 words) - 06:55, 10 June 2024
  • Thumbnail for Rheumatoid arthritis
    anti-TNFa/DMRADs combination therapy. For example, miRNA-16-5p, miRNA-23-3p, miRNA125b-5p, miRNA-126-3p, miRNA-146a-5p, miRNA-223-3p. Curious fact is that only responder...
    147 KB (17,112 words) - 06:46, 10 June 2024
  • On 6 January 2016, Wayan Mirna Salihin died in Abdi Waluyo Hospital after drinking a Vietnamese iced coffee at the Olivier Cafe in the Grand Indonesia...
    10 KB (982 words) - 02:25, 19 May 2024