• Thumbnail for Microsomal triglyceride transfer protein
    Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP, also known as MTP, gene. MTTP encodes the large...
    9 KB (1,093 words) - 02:00, 20 June 2024
  • Thumbnail for Abetalipoproteinemia
    Abetalipoproteinemia (also known as: Bassen–Kornzweig syndrome, microsomal triglyceride transfer protein deficiency disease, MTP deficiency, and betalipoprotein...
    21 KB (2,253 words) - 12:35, 20 October 2024
  • cardiovascular events. Lomitapide works to inhibit the microsomal triglyceride transfer protein (MTP) which results in a reduction of LDL plasma levels...
    31 KB (3,036 words) - 14:11, 12 November 2024
  • Microsome (redirect from Microsomal)
    studied the microsomal triglyceride transfer protein (MTP). MTP is an endoplasmic reticulum resident protein and assists in transferring neutral lipids...
    11 KB (1,551 words) - 02:54, 2 July 2023
  • Thumbnail for Mediated transport
    Mediated transport (category Transport proteins)
    mediated transport protein is microsomal triglyceride transfer protein (MTTP) who is responsible for catalyzing the assembly of the triglyceride rich lipoproteins...
    9 KB (939 words) - 20:56, 14 April 2024
  • Thumbnail for Familial hypercholesterolemia
    intestine to bypass the liver. Lomitapide, an inhibitor of the microsomal triglyceride transfer protein, was approved by the US FDA in December 2012 as an orphan...
    48 KB (5,465 words) - 14:08, 6 September 2024
  • Vitellogenin (category Protein pages needing a picture)
    the Microsomal triglyceride transfer protein (MTTP) and in Apolipoprotein B. It aids cell trafficking and export of cargo.[citation needed] Microsomal triglyceride...
    17 KB (1,883 words) - 16:15, 7 August 2024
  • Thumbnail for Acanthocyte
    of the microsomal triglyceride transfer protein (MTTP) gene. Acanthocytes arise from either alterations in membrane lipids or structural proteins. Alterations...
    7 KB (733 words) - 20:34, 26 June 2024
  • Thumbnail for Dirlotapide
    Slentrol.[citation needed] It works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. This blocks the assembly and release...
    7 KB (451 words) - 23:33, 1 December 2023
  • program, a form of treatment for heroin addiction Microsomal triglyceride transfer protein, a liver protein linked to LDL release Mitochondrial permeability...
    4 KB (503 words) - 01:49, 16 May 2024
  • Thumbnail for Apolipoprotein B
    1056/NEJM198906153202407. ISSN 0028-4793. PMID 2725600. "MTTP microsomal triglyceride transfer protein [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih...
    40 KB (4,890 words) - 15:14, 7 September 2024
  • Thumbnail for Lomitapide
    apheresis in adults with HoFH. Lomitapide inhibits the microsomal triglyceride transfer protein (MTP or MTTP) which is necessary for very low-density lipoprotein...
    8 KB (426 words) - 11:57, 13 August 2023
  • inhibitor of dietary cholesterol absorption. Lomitapide is a microsomal triglyceride transfer protein inhibitor. PCSK9 inhibitors are monoclonal antibodies for...
    11 KB (1,251 words) - 17:11, 6 June 2024
  • Thumbnail for Mitratapide
    Yarvitan. Its mechanism of action involves inhibition of microsomal triglyceride transfer protein (MTP) which is responsible for the absorption of dietary...
    4 KB (249 words) - 17:50, 7 September 2024
  • mutated apolipoprotein B. Another form is associated with microsomal triglyceride transfer protein which causes abetalipoproteinemia.[citation needed] A third...
    4 KB (324 words) - 19:56, 30 October 2024
  • Thumbnail for AP-1 transcription factor
    A, Grunfeld C, Feingold KR (June 1998). "Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines". Journal of...
    41 KB (4,468 words) - 17:08, 21 September 2024
  • Thumbnail for AMP-activated protein kinase
    sterol regulatory element-binding protein 1c (SREBP1c), it inhibits synthesis of fatty acids, cholesterol, and triglycerides, and activates fatty acid uptake...
    65 KB (7,149 words) - 14:04, 13 November 2024
  • (June 2011). "A Small-Molecule Inhibitor of Enterocytic Microsomal Triglyceride Transfer Protein, SLx-4090: Biochemical, Pharmacodynamic, Pharmacokinetic...
    20 KB (1,693 words) - 16:58, 26 September 2024
  • Thumbnail for CREB-binding protein
    to export the macromolecule out of cells and storage. Microsomal triglyceride transfer protein (MTP) is responsible for lipoprotein assembly and secretion...
    52 KB (5,272 words) - 18:01, 17 September 2024
  • Thumbnail for P4HB
    P4HB (category Endoplasmic reticulum resident proteins)
    S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. P4HB can be nitrosylated, and elevation of nitrosylated...
    18 KB (2,123 words) - 22:57, 6 June 2024
  • MT-TP (category Protein pages needing a picture)
    during translation. MT-TP is responsible for coding the microsomal triglyceride transfer protein, which is required for the synthesis of beta-lipoproteins...
    8 KB (910 words) - 03:54, 15 June 2024
  • Diamond, Louis K; Shwachman, Harry (October 1961). "Anemia associated with protein deficiency". The Journal of Pediatrics. 59 (4). Elsevier Inc: 533–42. doi:10...
    70 KB (2,582 words) - 03:15, 16 December 2023
  • Thumbnail for Apolipoprotein O
    Apolipoprotein O (category Protein pages needing a picture)
    amino acids protein that contains a 23 amino acids long signal peptide. The apoprotein is secreted by a microsomal triglyceride transfer protein (MTTP)-dependent...
    2 KB (276 words) - 12:57, 27 March 2022
  • Thumbnail for Protein–protein interaction
    muscle lipid droplet-associated proteins family associate with other proteins, as activator of adipose triglyceride lipase and its coactivator comparative...
    74 KB (8,391 words) - 13:32, 2 November 2024
  • Thumbnail for Phosphatidylethanolamine N-methyltransferase
    Jo YJ, Park YS, Chae JD (Jun 2009). "Polymorphisms of microsomal triglyceride transfer protein gene and phosphatidylethanolamine N-methyltransferase gene...
    31 KB (3,536 words) - 22:28, 27 March 2024
  • Barba, G., Brechot, C. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion:a...
    16 KB (2,258 words) - 15:04, 23 June 2024
  • Thumbnail for Flavin adenine dinucleotide
    associated with various proteins, which is involved with several enzymatic reactions in metabolism. A flavoprotein is a protein that contains a flavin...
    39 KB (4,310 words) - 14:35, 24 September 2024
  • Thumbnail for ABCG8
    ABCG8 (category Membrane protein stubs)
    and of microsomal triglyceride transfer protein". Diabetologia. 49 (5): 1008–16. doi:10.1007/s00125-006-0177-8. PMID 16518588. ABCG8+protein,+human at...
    9 KB (1,153 words) - 00:43, 27 February 2024
  • Thumbnail for CYP2E1
    2165/00023210-200115060-00005. PMID 11524025. S2CID 13197188. Lieber CS (Jun 1999). "Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review"...
    26 KB (2,965 words) - 14:57, 8 November 2024
  • Thumbnail for 1-Lysophosphatidylcholine
    known to catalyze this reaction. LRAT-like protein (RLP-1; a product of the gene HRASLS5), catalyzes transfer of an acyl group from phosphatidylcholine...
    25 KB (2,167 words) - 15:26, 3 February 2024