A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin...
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A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action...
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reuptake inhibitor (NRI, NERI) or noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor...
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concentrations of synaptic monoamines. Monoamine reuptake inhibitor Dopamine reuptake inhibitor Norepinephrine reuptake inhibitor Stephen M. Stahl (2 March...
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type of monoamine reuptake inhibitor (MRI); other types of MRIs include dopamine reuptake inhibitors and norepinephrine reuptake inhibitors. SRIs are...
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(OCD), and migraine prevention. SNRIs are monoamine reuptake inhibitors; specifically, they inhibit the reuptake of serotonin and norepinephrine. These neurotransmitters...
78 KB (7,687 words) - 09:12, 6 April 2024
reuptake inhibitor (SNDRI), also known as a triple reuptake inhibitor (TRI), is a type of drug that acts as a combined reuptake inhibitor of the...
128 KB (15,244 words) - 05:38, 25 July 2024
reuptake inhibitor Monoamine reuptake inhibitor Dopamine reuptake inhibitor Norepinephrine reuptake inhibitor Serotonin reuptake inhibitor Serotonin-norepinephrine...
19 KB (1,909 words) - 02:26, 28 March 2024
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
37 KB (4,031 words) - 17:55, 16 August 2024
monoamine reuptake inhibitor and/or receptor modulator) Amoxapine (Asendin) – tetracyclic antidepressant (non-selective monoamine reuptake inhibitor and/or...
96 KB (7,785 words) - 04:17, 15 August 2024
A serotonin–dopamine reuptake inhibitor (SDRI) is a type of drug which acts as a reuptake inhibitor of the monoamine neurotransmitters serotonin and dopamine...
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patients at risk of substance abuse. Norepinephrine reuptake inhibitor Monoamine reuptake inhibitor Ding, Y.-S.; Naganawa, M.; Gallezot, J.-D.; Nabulsi...
34 KB (3,819 words) - 14:10, 24 July 2024
limiting its reabsorption (reuptake) into the presynaptic cell. They have varying degrees of selectivity for the other monoamine transporters, with pure...
129 KB (14,095 words) - 06:22, 6 August 2024
Tesofensine (category Serotonin–norepinephrine–dopamine reuptake inhibitors)
Tesofensine (NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the...
16 KB (1,763 words) - 20:54, 16 August 2024
(Nopron) – a drug related to this group but does not inhibit the reuptake of serotonin or the other monoamines. Medifoxamine (Clédial, Gerdaxyl) – could perhaps...
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Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
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Methylphenidate targets DAT as a non-selective reuptake inhibitor. Methylphenidate is not an inhibitor of SERT. It has been observed that the pathology...
21 KB (2,342 words) - 01:36, 18 May 2024
Desmethylsertraline (category Serotonin–norepinephrine–dopamine reuptake inhibitors)
as a serotonin reuptake inhibitor (Ki = 76 nM vs. 3 nM, respectively), but conversely, is more balanced as a monoamine reuptake inhibitor (5-HT (Ki) = 76 nM;...
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The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
43 KB (4,990 words) - 08:07, 27 June 2024
Trimipramine (section Monoamine reuptake inhibition)
TCA because, unlike other TCAs, it seems to be a fairly weak monoamine reuptake inhibitor. Similarly to other TCAs, however, trimipramine does have antihistamine...
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Benzofuranylpropylaminopentane (category Serotonin–norepinephrine–dopamine reuptake inhibitors)
and dopamine. At much higher concentrations, BPAP is also a monoamine reuptake inhibitor, specifically of dopamine and norepinephrine and to a much lesser...
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member 2 (SLC6A2) gene. NET is a monoamine transporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent reuptake of extracellular norepinephrine...
31 KB (3,397 words) - 02:14, 21 December 2023
An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine...
16 KB (1,581 words) - 20:02, 10 March 2024
inside the presynaptic neuron, they may inhibit the reuptake of monoamine neurotransmitters through vesicular monoamine transporter 2 (VMAT2) and release the...
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Isocarboxazid (category Monoamine oxidase inhibitors)
(Marplan, Marplon, Enerzer) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant. Along...
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Indatraline (category Serotonin–norepinephrine–dopamine reuptake inhibitors)
19-005) is an antidepressive agent and non-selective monoamine transporter inhibitor that blocks the reuptake of dopamine, norepinephrine, and serotonin with...
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Ethylphenidate (category Norepinephrine–dopamine reuptake inhibitors)
methylphenidate. Ethylphenidate acts as both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of the...
17 KB (1,605 words) - 20:35, 17 August 2024
ketamine and the monoamine oxidase inhibitor (MAOI) tranylcypromine, which is of importance as the combination of a monoamine reuptake inhibitor with an MAOI...
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Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring...
40 KB (4,627 words) - 23:14, 15 May 2024
Tetrahydroharmine (category Serotonin reuptake inhibitors)
harmaline and harmine, is a reversible inhibitor of monoamine oxidase A (RIMA), but it also inhibits the reuptake of serotonin. THH contributes to B. caapi's...
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