• Thumbnail for Muscarinic acetylcholine receptor M4
    The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the...
    20 KB (2,130 words) - 04:59, 2 December 2024
  • Thumbnail for Muscarinic acetylcholine receptor M3
    muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded...
    16 KB (1,761 words) - 05:18, 24 October 2024
  • Thumbnail for Muscarinic acetylcholine receptor M1
    The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the...
    22 KB (2,227 words) - 08:51, 26 October 2024
  • Thumbnail for Muscarinic acetylcholine receptor M2
    The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is...
    19 KB (2,091 words) - 17:29, 25 September 2024
  • Thumbnail for Muscarinic acetylcholine receptor
    Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
    36 KB (3,151 words) - 04:36, 9 December 2024
  • Thumbnail for Muscarinic acetylcholine receptor M5
    The human muscarinic acetylcholine receptor M5, encoded by the CHRM5 gene, is a member of the G protein-coupled receptor superfamily of integral membrane...
    13 KB (1,511 words) - 04:39, 20 October 2024
  • Thumbnail for Acetylcholine receptor
    "ionotropic" acetylcholine receptors) are particularly responsive to nicotine. The nicotine ACh receptor is also a Na+, K+ and Ca2+ ion channel. Muscarinic acetylcholine...
    13 KB (1,309 words) - 04:20, 6 December 2024
  • Thumbnail for Acetylcholine
    proliferative signals via a membrane-located M1-muscarinic receptor homolog. Partly because of acetylcholine's muscle-activating function, but also because...
    41 KB (4,382 words) - 05:15, 9 November 2024
  • Thumbnail for Muscarinic agonist
    A muscarinic acetylcholine receptor agonist, also simply known as a muscarinic agonist or as a muscarinic agent, is an agent that activates the activity...
    9 KB (858 words) - 23:25, 21 November 2024
  • Thumbnail for Muscarinic antagonist
    A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic...
    41 KB (2,060 words) - 02:02, 24 November 2024
  • myelomonocytic leukemia Muscarinic acetylcholine receptor M4, a protein Apple M4, a central processing unit in the Apple M series m4 (computer language),...
    5 KB (685 words) - 02:08, 15 December 2024
  • Thumbnail for Emraclidine
    Emraclidine (category M4 receptor positive allosteric modulators)
    allosteric modulator that selectively targets the muscarinic acetylcholine receptor M4 subtype. The M4 receptor subtype is expressed in the striatum of the...
    4 KB (246 words) - 03:10, 31 October 2024
  • Thumbnail for Xanomeline
    Xanomeline (category M4 receptor agonists)
    central nervous system muscarinic M1 and M4 receptor subtypes. Xanomeline is a non-selective muscarinic acetylcholine receptor agonist with similar high...
    22 KB (1,772 words) - 23:58, 9 December 2024
  • Thumbnail for Xanomeline/trospium chloride
    Xanomeline/trospium chloride (category M4 receptor agonists)
    xanomeline, a muscarinic agonist; and trospium chloride, a muscarinic antagonist. Xanomeline is a functionally preferring muscarinic M4 and M1 receptor agonist...
    18 KB (1,561 words) - 07:10, 16 November 2024
  • Thumbnail for Dopaminergic pathways
    by muscarinic acetylcholine receptors. In particular, the activation of muscarinic acetylcholine receptor M2 and muscarinic acetylcholine receptor M4 inhibits...
    47 KB (4,256 words) - 15:23, 6 September 2024
  • Thumbnail for Pirenzepine
    Pirenzepine (category M4 receptor antagonists)
    reduces muscle spasm. It is in a class of drugs known as muscarinic receptor antagonists; acetylcholine is the neurotransmitter of the parasympathetic nervous...
    4 KB (254 words) - 02:50, 26 October 2024
  • Thumbnail for Cortico-basal ganglia-thalamo-cortical loop
    monosynaptic connections driven by dopamine receptor D1, adenosine A1 receptor, and muscarinic acetylcholine receptor M4, while the indirect pathway relies on...
    14 KB (1,784 words) - 09:38, 6 August 2023
  • Thumbnail for Desmethylclozapine
    Desmethylclozapine (category M4 receptor antagonists)
    muscarinic acetylcholine M1 receptor and the δ-opioid receptor, unlike clozapine as well. It is a moderate-efficacy partial agonist of the muscarinic...
    7 KB (639 words) - 23:57, 14 November 2024
  • Thumbnail for Bethanechol
    Bethanechol (category M4 receptor agonists)
    carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine, bethanechol is not hydrolyzed by...
    7 KB (390 words) - 06:52, 25 October 2024
  • Thumbnail for Parasympathetic nervous system
    Sympathetic nervous system Acetylcholine Choline Cholinergic receptor Nicotinic acetylcholine receptor Muscarinic acetylcholine receptor Langley, John Newport...
    31 KB (3,865 words) - 01:13, 16 December 2024
  • ML-007 (category M4 receptor agonists)
    ML-007 is a selective muscarinic acetylcholine M1 and M4 receptor agonist which is under development for the treatment of schizophrenia, psychotic disorders...
    4 KB (231 words) - 18:12, 6 November 2024
  • Thumbnail for Trospium chloride
    Trospium chloride (category M4 receptor antagonists)
    affinity for all five of the muscarinic acetylcholine receptor subtypes, including the M1, M2, M3, M4, and M5 receptors. After oral administration, less...
    22 KB (2,087 words) - 06:58, 12 November 2024
  • Thumbnail for PD-102,807
    PD-102,807 (category M4 receptor antagonists)
    for the muscarinic acetylcholine receptor M4. It is used in scientific research for studying the effects of the different muscarinic receptor subtypes...
    4 KB (343 words) - 04:41, 26 October 2024
  • Thumbnail for Cyclobenzaprine
    Cyclobenzaprine (category H1 receptor antagonists)
    acetylcholine M1, M2, and M3 receptors, but not of the muscarinic acetylcholine M4 or M5 receptor. The mechanism of action of cyclobenzaprine as a muscle...
    31 KB (2,429 words) - 04:38, 5 December 2024
  • Thumbnail for Basal ganglia
    neurons (MSNs) that express dopamine receptor D1, muscarinic acetylcholine receptor M4, and adenosine receptor A1. The direct pathway has been proposed...
    59 KB (6,553 words) - 03:56, 19 September 2024
  • Thumbnail for Muscarine
    Muscarine (category M4 receptor agonists)
    concentrations up to 1.6%. Muscarine is a selective agonist of the muscarinic acetylcholine receptors. The name muscarine derives from that of Amanita muscaria...
    18 KB (1,882 words) - 06:42, 25 October 2024
  • Thumbnail for Muscarinic toxin 2
    interactions of muscarinic toxins studied using tritiated 3H-N-methyl scopolamine (NMS) with human muscarinic receptor subtypes m1, m2, m3 and m4 has shown...
    2 KB (204 words) - 04:19, 26 October 2024
  • Thumbnail for Adrenergic receptor
    adrenergic receptor kinase Beta adrenergic receptor kinase-2 Acetylcholine receptor (Cholinergic receptor) Nicotinic acetylcholine receptor Muscarinic acetylcholine...
    33 KB (2,982 words) - 15:21, 27 November 2024
  • Thumbnail for Methacholine
    Methacholine (category M4 receptor agonists)
    acetyl-β-methylcholine, is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. Methacholine is primarily...
    6 KB (383 words) - 04:14, 26 October 2024
  • Thumbnail for Scopolamine
    Scopolamine (category M4 receptor antagonists)
    central muscarinic acetylcholine receptors. Scopolamine acts as a nonspecific muscarinic antagonist at all four (M1, M2, M3, and M4) receptor sites. In...
    59 KB (5,256 words) - 20:55, 27 November 2024