Neuregulin 1, or NRG1, is a gene of the epidermal growth factor family that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the...
32 KB (3,921 words) - 10:13, 27 March 2024
Neuregulins are a family of four structurally related proteins that are part of the EGF family of proteins. These proteins have been shown to have diverse...
8 KB (867 words) - 15:29, 1 January 2024
Neuregulin 3, also known as NRG3, is a neural-enriched member of the neuregulin protein family which in humans is encoded by the NRG3 gene. The NRGs are...
20 KB (2,559 words) - 22:14, 8 November 2023
Neuregulin 2, also known as NRG2, is a protein which in humans is encoded by the NRG2 gene. Neuregulin 2 (NRG2) is a novel member of the neuregulin family...
6 KB (726 words) - 09:40, 13 October 2022
Schwann cell (section Neuregulin 1)
SOX10 might influence early glial precursors to respond to neuregulin 1 (see below). Neuregulin 1 (NRG1) acts in a number of ways to both promote the formation...
19 KB (2,450 words) - 12:37, 19 June 2024
Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by the NRG4 gene. The neuregulins, including NRG4...
3 KB (413 words) - 16:15, 25 September 2022
protein (HGFLP) Myostatin (GDF-8) Neuregulins Neuregulin 1 (NRG1) Neuregulin 2 (NRG2) Neuregulin 3 (NRG3) Neuregulin 4 (NRG4) Neurotrophins Brain-derived...
10 KB (1,131 words) - 19:14, 31 March 2024
Epiregulin (EPR) Epigen Betacellulin (BTC) neuregulin-1 (NRG1) neuregulin-2 (NRG2) neuregulin-3 (NRG3) neuregulin-4 (NRG4). All family members contain one...
17 KB (1,708 words) - 13:56, 21 July 2024
were homozygous for the mutant neuregulin gene. However, when wild-type neuregulin was added to homozygous mutant neuregulin explants (isolated tissue cell...
28 KB (3,157 words) - 13:09, 8 March 2024
within the UK Conservative Party Neuregulins: Neuregulin 1 or NRG1 Neuregulin 2 or NRG2 Neuregulin 3 or NRG3 Neuregulin 4 or NRG4 Psychoactive compounds:...
2 KB (260 words) - 15:10, 25 May 2024
with schizophrenia-like behavioural deficits. The gene NRG1 codes for neuregulin 1, a growth factor which is crucial to the development of the nervous...
24 KB (2,785 words) - 21:37, 14 August 2024
clinical efficacy in HER2 overexpressing breast cancers by disrupting a neuregulin-1 (NRG1)-mediated autocrine loop. In the case of PDGFR signalling, overexpression...
18 KB (2,105 words) - 01:40, 20 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
121 KB (13,799 words) - 18:32, 22 August 2024
One of which is erbB-2, and the other members being erbB-1, erbB-3 (neuregulin-binding; lacks kinase domain), and erbB-4. All four contain an extracellular...
43 KB (4,651 words) - 13:41, 27 July 2024
receptor adopts a conformation that inhibits dimerization. Binding of neuregulin to the ligand binding subdomains (I and III) induces a conformational...
24 KB (2,812 words) - 07:28, 23 August 2024
a PDZ domain binding motif. The protein binds to and is activated by neuregulins-2, -3 and -4, heparin-binding EGF-like growth factor and betacellulin...
12 KB (1,597 words) - 14:14, 22 December 2023
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
68 KB (5,999 words) - 20:41, 31 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
149 KB (15,717 words) - 06:34, 13 August 2024
disorder becomes.[citation needed] Common and rare DNA variations in the neuregulin 1 (NRG1) and NRG3 (NRG3) were first shown to be associated with the disease...
36 KB (3,881 words) - 05:56, 31 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
92 KB (8,671 words) - 18:15, 17 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
73 KB (6,440 words) - 02:59, 3 September 2024
down-regulate GluN2B and activate GluN2C, a process that is independent of neuregulin beta signaling through ErbB2 and ErbB4 receptors. NMDA receptors have...
107 KB (12,051 words) - 22:31, 22 July 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
34 KB (3,021 words) - 12:39, 5 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
5 KB (412 words) - 23:17, 19 June 2023
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
24 KB (1,710 words) - 19:18, 30 August 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
13 KB (1,177 words) - 00:03, 12 August 2024
amphiregulin + - - - betacellulin + - - + epigen + - - - epiregulin + - - + neuregulin 1 - - + + neuregulin 2 - - + + neuregulin 3 - - - + neuregulin 4 - - - +...
24 KB (2,736 words) - 00:12, 28 November 2023
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
31 KB (3,430 words) - 05:24, 28 August 2024
Products Acetylcholine receptor inducing activity, an alternative name for neuregulin type 1 Amyloid-related imaging abnormalities, a side effect of monoclonal...
5 KB (646 words) - 18:35, 1 June 2024
Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies: Duligotumab Patritumab...
42 KB (3,935 words) - 04:01, 30 April 2024