• Thumbnail for Neuregulin 3
    Neuregulin 3, also known as NRG3, is a neural-enriched member of the neuregulin protein family which in humans is encoded by the NRG3 gene. The NRGs are...
    20 KB (2,559 words) - 22:14, 8 November 2023
  • Thumbnail for Neuregulin
    Neuregulins are a family of four structurally related proteins that are part of the EGF family of proteins. These proteins have been shown to have diverse...
    8 KB (867 words) - 15:29, 1 January 2024
  • Thumbnail for Neuregulin 1
    Neuregulin 1, or NRG1, is a gene of the epidermal growth factor family that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the...
    32 KB (3,921 words) - 10:13, 27 March 2024
  • protein (HGFLP) Myostatin (GDF-8) Neuregulins Neuregulin 1 (NRG1) Neuregulin 2 (NRG2) Neuregulin 3 (NRG3) Neuregulin 4 (NRG4) Neurotrophins Brain-derived...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Epidermal growth factor
    Epiregulin (EPR) Epigen Betacellulin (BTC) neuregulin-1 (NRG1) neuregulin-2 (NRG2) neuregulin-3 (NRG3) neuregulin-4 (NRG4). All family members contain one...
    17 KB (1,735 words) - 03:22, 28 February 2024
  • Thumbnail for Neuregulin 2
    Neuregulin 2, also known as NRG2, is a protein which in humans is encoded by the NRG2 gene. Neuregulin 2 (NRG2) is a novel member of the neuregulin family...
    6 KB (726 words) - 09:40, 13 October 2022
  • Thumbnail for Neuregulin 4
    Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by the NRG4 gene. The neuregulins, including NRG4...
    3 KB (413 words) - 16:15, 25 September 2022
  • within the UK Conservative Party Neuregulins: Neuregulin 1 or NRG1 Neuregulin 2 or NRG2 Neuregulin 3 or NRG3 Neuregulin 4 or NRG4 Psychoactive compounds:...
    2 KB (260 words) - 15:10, 25 May 2024
  • Thumbnail for Schwann cell
    SOX10 might influence early glial precursors to respond to neuregulin 1 (see below). Neuregulin 1 (NRG1) acts in a number of ways to both promote the formation...
    19 KB (2,448 words) - 12:37, 19 June 2024
  • Thumbnail for ERBB3
    ERBB3 (redirect from Her 3)
    1016/S0021-9258(17)36789-3. PMID 8188716. Carraway KL, Weber JL, Unger MJ, Ledesma J, Yu N, Gassmann M, Lai C (1997). "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor...
    23 KB (2,751 words) - 14:34, 6 June 2024
  • and display abnormal development of the peripheral nervous system. In ErbB-3 receptor mutant mice, they have less severe defects in the heart and thus...
    24 KB (2,736 words) - 00:12, 28 November 2023
  • specifically, Lin et al. demonstrated that SNORD90 can reduce the expression of neuregulin 3 (NRG3). The precise effect of the methylation and pseudouridylation modifications...
    31 KB (3,791 words) - 13:33, 9 January 2024
  • Thumbnail for ERBB4
    phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins-2, -3 and -4, heparin-binding...
    12 KB (1,597 words) - 14:14, 22 December 2023
  • Thumbnail for Small nucleolar RNA SNORD90
    transcripts. Specifically, SNORD90 has been shown to increase m6A levels on neuregulin 3 (NRG3) leading to its down-regulation through recognition by YTHDF2....
    3 KB (293 words) - 03:34, 25 November 2023
  • Thumbnail for Testosterone
    Thyroid Diseases. Endocrinology. pp. 1–22. doi:10.1007/978-3-319-29456-8_11-1. ISBN 978-3-319-29195-6. Archived from the original on April 7, 2024. Retrieved...
    150 KB (15,741 words) - 10:52, 27 June 2024
  • Thumbnail for Gerald Fischbach
    were homozygous for the mutant neuregulin gene. However, when wild-type neuregulin was added to homozygous mutant neuregulin explants (isolated tissue cell...
    28 KB (3,157 words) - 13:09, 8 March 2024
  • Thumbnail for Neurotrophin-3
    Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Thumbnail for Integrin beta 3
    Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The...
    9 KB (1,050 words) - 17:56, 13 January 2024
  • Thumbnail for Animal model of schizophrenia
    with schizophrenia-like behavioural deficits. The gene NRG1 codes for neuregulin 1, a growth factor which is crucial to the development of the nervous...
    24 KB (2,793 words) - 17:30, 23 April 2024
  • Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1)...
    5 KB (412 words) - 23:17, 19 June 2023
  • Thumbnail for IGFBP3
    growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins...
    39 KB (4,717 words) - 13:09, 2 June 2024
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster of differentiation...
    17 KB (1,955 words) - 06:59, 15 April 2024
  • Thumbnail for HER2
    kinases. One of which is erbB-2, and the other members being erbB-1, erbB-3 (neuregulin-binding; lacks kinase domain), and erbB-4. All four contain an extracellular...
    43 KB (4,776 words) - 13:06, 5 July 2024
  • Thumbnail for Hirschsprung's disease
    disorder becomes.[citation needed] Common and rare DNA variations in the neuregulin 1 (NRG1) and NRG3 (NRG3) were first shown to be associated with the disease...
    36 KB (3,871 words) - 12:47, 4 April 2024
  • clinical efficacy in HER2 overexpressing breast cancers by disrupting a neuregulin-1 (NRG1)-mediated autocrine loop. In the case of PDGFR signalling, overexpression...
    18 KB (2,105 words) - 17:15, 1 December 2023
  • Thumbnail for Beta-secretase 1
    observed that BACE1 is involved in myelination (it is co-express with neuregulin 1 type III). In a manner analogous to APP processing, the VGSC subunit...
    18 KB (2,088 words) - 19:48, 26 June 2024
  • des(1-3)IGF-1 is a naturally occurring, endogenous protein, as well as drug, and truncated analogue of insulin-like growth factor 1 (IGF-1). des(1-3)IGF-1...
    4 KB (346 words) - 21:33, 11 November 2023
  • Thumbnail for Fruquintinib
    NCT02314819 for "A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer participants (FRESCO) (FRESCO)" at ClinicalTrials...
    10 KB (579 words) - 06:46, 26 June 2024
  • trophic factors - like ciliary neurotrophic factor (CNTF), cytokines or neuregulin 1 (NRG1) - that can determine whether the cells will differentiate into...
    18 KB (2,122 words) - 17:09, 23 February 2024
  • Thumbnail for VEGF receptor
    VEGF receptor (redirect from VEGFR-3)
    factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending on alternative splicing, they may be membrane-bound (mbVEGFR) or...
    8 KB (755 words) - 18:51, 2 November 2023