Neuropilin-1 is a protein that in humans is encoded by the NRP1 gene. In humans, the neuropilin 1 gene is located at 10p11.22. This is one of two human...

Neuropilin is a protein receptor active in neurons. There are two forms of Neuropilins, NRP-1 and NRP-2. Neuropilins are transmembrane glycoproteins, first...

Neuropilin 2 (NRP2) is a protein that in humans is encoded by the NRP2 gene. This gene encodes a member of the neuropilin family of receptor proteins...

VEGF-A, expressed at the midline, which signals through the receptor Neuropilin-1 (NRP1) expressed on RGC axons. Chiasm crossing is also promoted by Nr-CAM...

features that differentiate tTreg and iTreg cells include Helios and Neuropilin-1, the presence of which suggests origin in the thymus. Another feature...

the midline directs RGCs to take a contralateral path, mediated by the neuropilin-1 (NRP1) receptor. cAMP seems to be very important in regulating the production...

regulates cellular uptake and vascular permeability through interaction with neuropilin-1. The CendR motif has a consensus (R/K)XX(R/K) and it is able to interact...

be a VEGF receptor by Terman et al. in 1992 as well. In 1998, neuropilin 1 and neuropilin 2 were shown to act as VEGF receptors. In mammals, the VEGF family...

Mutant GlysRS interferes with neuronal transmembrane receptors, including neuropilin 1 (Nrp1) and vascular endothelial growth factor (VEGF), causing neuropathy...

This second step is mediated through specific secondary binding to neuropilin-1 receptor, and subsequent activation of a trans-tissue pathway, dubbed...

The pathfinding defect occurs via the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor...

Gechtman Z, Kutcher ME, Gasiunas N, Gallagher J, Klagsbrun M (July 2002). "Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2...

Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M (March 1998). "Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor...

teams publish two preprints on 5 June and 10 June according to which Neuropilin-1 (NRP1) is a second protein that SARS-CoV-2 uses to enter human cells...

for axons of neurons is signaled through receptor complexes containing Neuropilin-1 (NRP1) and a co-receptor. One of the first identified intracellular messenger...

serine 2 (TMPRSS2) is essential for entry of SARS‑CoV‑2. The host protein neuropilin 1 (NRP1) may aid the virus in host cell entry using ACE2. After a SARS‑CoV‑2...

Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M (March 1998). "Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor...

vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1". The Journal of Biological Chemistry. 274 (30): 21217–22. doi:10.1074/jbc...

Vignali's group pioneered the identification of a pathway involving neuropilin-1 (NRP1) and semaphorin-4a (SEMA4A), crucial for maintaining intratumoral...

the C-terminus of the peptide. Subsequent binding of the peptide to neuropilin-1 activates the CendR transport pathway into and through tumor tissue....

transmission, and axonal transport. Semaphorins are the main ligands for the Neuropilin 1 (Npn1) receptor; this receptor is typically located in the medial and...

Flt 1". Oncogene. 16 (3): 359–67. doi:10.1038/sj.onc.1201545. PMID 9467961. Gluzman-Poltorak Z, Cohen T, Herzog Y, Neufeld G (June 2000). "Neuropilin-2...

vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1". The Journal of Biological Chemistry. 274 (30): 21217–21222. doi:10...

CEND-1, also known as iRGD, is a cyclic peptide that homes to tumors via binding to integrin alpha V receptors. It also binds and activates neuropilin-1,...

Leforban B, Dufour S, Liu WQ, et al. (January 2012). "Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial...

characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1". J. Neurosci...

involves axonal guidance molecules such as sema3A (semaphorin 3A) and (neuropilin). Neuroangiogenic and axonal guidance molecules act on both neuronal growth...

A; Price, Timothy (October 2022). "Dual αV-integrin and neuropilin-1 targeting peptide CEND-1 plus nab-paclitaxel and gemcitabine for the treatment of...

dose-escalation and dose-expansion phase 1 study". The Lancet Oncology. 16 (8): 949–956. doi:10.1016/S1470-2045(15)00132-1. PMID 26179200. https://www.regeneron...

mediating repulsive signal. Sema3A initiates clustering of the receptor neuropilin 1 and plexin A1. While some of the other class of semaphorins directly...