• Thumbnail for Osteoprotegerin
    Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B)...
    30 KB (3,687 words) - 20:28, 17 May 2024
  • Thumbnail for RANKL
    member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a protein...
    28 KB (3,309 words) - 05:21, 5 August 2024
  • Thumbnail for Non-communicable disease
    increased levels in patients at risk for cardiovascular disease. Also osteoprotegerin which involved with regulation of a key inflammatory transcription...
    29 KB (3,354 words) - 03:24, 13 August 2024
  • Thumbnail for Osteoclast
    to be RANKL dependent. Osteoclast differentiation is inhibited by osteoprotegerin (OPG), which is produced by osteoblasts and binds to RANKL thereby...
    26 KB (2,925 words) - 20:28, 17 May 2024
  • Thumbnail for Parathyroid hormone
    increase their expression of RANKL and inhibits their secretion of osteoprotegerin (OPG). Free OPG competitively binds to RANKL as a decoy receptor, preventing...
    34 KB (4,157 words) - 07:52, 21 May 2024
  • Thumbnail for Tooth resorption
    ligand (RANKL), also called osteoclast differentiation factor (ODF) and osteoprotegerin ligand (OPGL), is a regulator of osteoclast function. In physiological...
    17 KB (1,818 words) - 04:48, 24 July 2024
  • Thumbnail for Bone
    rate at which osteoclasts resorb bone is inhibited by calcitonin and osteoprotegerin. Calcitonin is produced by parafollicular cells in the thyroid gland...
    76 KB (8,829 words) - 02:50, 18 August 2024
  • OPG may refer to: Osteoprotegerin Office of the Public Guardian (disambiguation) Office of HM Paymaster General Online Policy Group Ontario Power Generation...
    391 bytes (67 words) - 17:03, 15 March 2024
  • Thumbnail for NF-κB
    NF-κB. Osteoprotegerin (OPG), which is a decoy receptor homolog for RANK ligand (RANKL), inhibits RANK by binding to RANKL, and, thus, osteoprotegerin is...
    89 KB (9,817 words) - 08:00, 10 June 2024
  • Thumbnail for Denosumab
    binding to and inhibiting RANKL. Denosumab mimics the natural action of osteoprotegerin, an endogenous RANKL inhibitor, that presents with decreasing concentrations...
    26 KB (2,188 words) - 05:17, 13 June 2024
  • Thumbnail for RANK
    node development, thermal regulation, and mammary gland development. Osteoprotegerin (OPG) is a decoy receptor for RANKL, and regulates the stimulation...
    23 KB (3,035 words) - 06:16, 25 December 2023
  • Thumbnail for Giant-cell tumor of bone
    , Xu J, Wood DJ, Zheng MH (2000). "Gene Expression of Osteoprotegerin Ligand, Osteoprotegerin, and REceptor Activator of NF-kB in Giant Cell Tumor of...
    14 KB (1,604 words) - 22:41, 29 February 2024
  • Thumbnail for Interleukin 1 beta
    ultimately lead to the secretion of the RANK/RANKL inhibitor osteoprotegerin. Higher osteoprotegerin and IL-1β levels are a characteristic of breast cancer...
    26 KB (3,305 words) - 17:31, 8 August 2024
  • Thumbnail for Osteoporosis
    lymphocytes), and stimulates RANK (receptor activator of nuclear factor κB). Osteoprotegerin (OPG) binds RANKL before it has an opportunity to bind to RANK, and...
    124 KB (13,984 words) - 10:50, 13 August 2024
  • bloodstream. PTHrP also acts by activating rank ligand and inhibiting osteoprotegerin which activates nuclear factor kappa B, which causes further activation...
    34 KB (3,298 words) - 19:13, 25 July 2024
  • chemokines Interleukin-8 and eotaxin-3, endothelin-1, angiopoietin-2, osteoprotegerin, the P-selectin cofactor CD63/lamp3, and α-1,3-fucosyltransferase VI...
    9 KB (1,123 words) - 08:48, 28 May 2024
  • Thumbnail for Pulmonary hypertension
    PMC 4117578. PMID 4117578. Lawrie A (December 2014). "The role of the osteoprotegerin/tumor necrosis factor related apoptosis-inducing ligand axis in the...
    89 KB (8,902 words) - 09:54, 15 August 2024
  • Thumbnail for Cortisol
    calcium resorption from bone – and also inhibits the production of osteoprotegerin (OPG) which acts as a decoy receptor and captures some RANKL before...
    78 KB (8,594 words) - 12:55, 16 August 2024
  • periodontal ligament undifferentiated mesenchymal cells. EMD also stimulates osteoprotegerin, serving to trigger osteoblasts and indirectly inhibit both osteoclastogenesis...
    4 KB (535 words) - 16:22, 18 June 2022
  • member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF). RANKL affects...
    96 KB (467 words) - 19:33, 6 August 2024
  • Fujikawa Y, Sabokbar A, Athanasou NA. (2000). The effect of osteoprotegerin and osteoprotegerin ligand on human arthroplasty macrophage-osteoclast differentiation...
    9 KB (1,115 words) - 12:37, 6 August 2024
  • Thumbnail for CCR5
    DR5 (TNFRSF10B) DcR1 (TNFRSF10C) DcR2 (TNFRSF10D) RANK (TNFRSF11A) Osteoprotegerin (TNFRSF11B) TweakR (TNFRSF12A) TACI (TNFRSF13B) BAFFR (TNFRSF13C) HVEM...
    67 KB (7,845 words) - 11:20, 5 August 2024
  • Thumbnail for Strontium ranelate
    formation. Strontium ranelate also stimulates osteoblasts to secrete osteoprotegerin in inhibiting osteoclasts formed from pre-osteoclasts in relation to...
    16 KB (1,537 words) - 19:09, 12 May 2024
  • Thumbnail for B-cell maturation antigen
    DR5 (TNFRSF10B) DcR1 (TNFRSF10C) DcR2 (TNFRSF10D) RANK (TNFRSF11A) Osteoprotegerin (TNFRSF11B) TweakR (TNFRSF12A) TACI (TNFRSF13B) BAFFR (TNFRSF13C) HVEM...
    18 KB (1,937 words) - 21:50, 5 January 2024
  • Thumbnail for KIT (gene)
    DR5 (TNFRSF10B) DcR1 (TNFRSF10C) DcR2 (TNFRSF10D) RANK (TNFRSF11A) Osteoprotegerin (TNFRSF11B) TweakR (TNFRSF12A) TACI (TNFRSF13B) BAFFR (TNFRSF13C) HVEM...
    35 KB (4,117 words) - 00:12, 6 August 2024
  • Thumbnail for Placenta specific 8
    remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin". Int. J. Oncol. 43 (2): 365–74. doi:10.3892/ijo.2013.1954. PMC 3775580...
    3 KB (493 words) - 18:32, 25 November 2023
  • Thumbnail for Cytokine receptor
    DR5 (TNFRSF10B) DcR1 (TNFRSF10C) DcR2 (TNFRSF10D) RANK (TNFRSF11A) Osteoprotegerin (TNFRSF11B) TweakR (TNFRSF12A) TACI (TNFRSF13B) BAFFR (TNFRSF13C) HVEM...
    6 KB (442 words) - 05:35, 18 May 2024
  • Thumbnail for Dental follicle
    Nuclear factor kB ligand or osteoprotegerin pathway controls osteoclastogenesis. In the apex of the dental follicle, osteoprotegerin prevents osteoclast formation...
    26 KB (3,475 words) - 22:41, 17 April 2024
  • Thumbnail for TNF receptor superfamily
    TRAILR4, TRUNDD, CD264 TNFRSF10D 11 RANK (11A) CD265 TNFRSF11A RANKL Osteoprotegerin (11B) OCIF, TR1 TNFRSF11B 12 TWEAK receptor (12A) Fn14, CD266 TNFRSF12A...
    8 KB (501 words) - 01:30, 27 December 2023
  • Thumbnail for Scientific research on the International Space Station
    (Bisphosphonates) Commercial Biomedical Testing Module: Effects of Osteoprotegerin on Bone Maintenance in Microgravity (CBTM) Commercial Biomedical Test...
    203 KB (14,125 words) - 15:59, 9 May 2024