Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. Pax-7 plays a role in neural crest development and gastrulation, and...
11 KB (1,355 words) - 07:03, 21 July 2024
associated with ARMS, but are not necessary: PAX3-FKHR (now known as FOXO1) and PAX7-FKHR. In children and adolescents ARMS accounts for about 1 percent of all...
11 KB (1,310 words) - 15:42, 22 September 2024
are present in a subfamily along with the highly homologous human PAX7 and mouse Pax7 genes. The human PAX3 gene is located in the 2q36.1 chromosomal region...
35 KB (4,308 words) - 10:17, 11 August 2024
activation results in the progressive loss of Pax7 expression as they enter the proliferative stage. However, Pax7 is expressed prominently after satellite...
28 KB (3,408 words) - 16:25, 17 October 2024
complete absence of forelimb muscles. Associated genetic factors: PAX7 Mutations in Pax7 will prevent the formation of satellite cells and, in turn, prevent...
24 KB (2,738 words) - 02:09, 3 September 2024
several genetic risk factors. Six single-nucleotide polymorphisms in the PAX7 gene are implicated in the development of facial features. These variations...
8 KB (963 words) - 12:57, 5 November 2024
and PAX7 in clinical settings. This is attributed to the gooseberry genes gsb-proximal and gsb-distal showing similar function to PAX3 and PAX7. Waardenburg...
17 KB (1,670 words) - 03:13, 15 September 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
96 KB (10,011 words) - 05:08, 3 September 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
148 KB (14,786 words) - 23:22, 21 November 2024
functionality. Within chicks, frogs and fish Pax3/Pax7 are activated by Wnt and FGF signaling. Pax3 and Pax7 are also required for neural crest induction after...
16 KB (1,951 words) - 10:50, 18 October 2024
Both involve the translocation of a DNA binding domain of either PAX3 or PAX7, a member of the Paired Box family of transcription factors, to a transactivation...
50 KB (5,957 words) - 07:38, 4 August 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
111 KB (10,907 words) - 21:56, 12 November 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
80 KB (9,487 words) - 08:05, 19 November 2024
LEUTX; MIXL1; NOBOX; OTP; OTX1, OTX2, CRX; PAX2, PAX3, PAX4, PAX5, PAX6, PAX7, PAX8; PHOX2A, PHOX2B; PITX1, PITX2, PITX3; PROP1; PRRX1, PRRX2; RAX, RAX2;...
41 KB (4,385 words) - 21:28, 21 August 2024
usually a partial, or in the case of four family members (PAX3, PAX4, PAX6 and PAX7), a complete homeodomain to the C-terminus. An octapeptide as well as a Pro-Ser-Thr-rich...
10 KB (1,191 words) - 01:21, 10 March 2024
specifiers are induced as a set of transcription factors. Distalless-5, PAX3 and PAX7 prevent the border region from becoming either neural plate or epidermis...
18 KB (2,461 words) - 04:22, 16 July 2024
Paired box Known motif – High-throughput in vitro [679] YACGCHYSRNYRMNY PAX7 ENSG00000009709 Homeodomain; Paired box Known motif – High-throughput in...
374 KB (81 words) - 02:10, 23 September 2023
genes involved in muscle development, including MyoD, myogenin, desmin, and PAX7, and indeed DUX4 expression has shown to reduce muscle cell proliferation...
176 KB (16,456 words) - 00:30, 6 November 2024
transcription factors—Nkx2.2, Olig2, Nkx6.1, Nkx6.2, Dbx1, Dbx2, Irx3, Pax6, and Pax7—that is regulated by the SHH gradient. These transcription factors are induced...
62 KB (7,249 words) - 20:50, 23 September 2024
Embryonal rhabdomyosarcoma can be classified by its lack of PAX3–FOXO1 or PAX7–FOXO1 gene fusions, but approximately 20% of alveolar rhabdomyosarcomas are...
34 KB (3,763 words) - 19:44, 5 August 2024
HGNC:8618 O43316 11752 PAX5 HGNC:8619 Q02548 11753 PAX6 HGNC:8620 P26367 11754 PAX7 HGNC:8621 P23759 11755 PAX8 HGNC:8622 Q06710 11756 PAX9 HGNC:8623 P55771...
282 KB (17 words) - 08:00, 19 November 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
14 KB (1,341 words) - 22:41, 10 April 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
39 KB (4,281 words) - 21:02, 17 August 2024
induce cells in somites that receive these Wnt signals to express Pax3 and Pax7 in addition to myogenic regulatory factors, including Myf5 and MyoD. Specifically...
27 KB (3,374 words) - 10:55, 15 July 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
11 KB (1,093 words) - 11:40, 13 November 2024
notochord, fin, and muscle The blastema that is formed expresses PAX3 and PAX7, which is associated with activation of muscle stem cells. This specific...
23 KB (2,692 words) - 23:19, 17 March 2024
liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
21 KB (1,923 words) - 15:37, 21 June 2024
FGFR2, FOXE1, IRF6, MAFB (gene), MMP3, MSX1, MSX2 (Msh homeobox 2), MSX3, PAX7, PDGFC, PTCH1, SATB2, SOX9, SUMO1 (Small ubiquitin-related modifier 1), TBX22...
6 KB (610 words) - 06:40, 1 May 2024
translocations including translocation of the FOXO1 gene fusing with the PAX3 or PAX7 gene. In the neuroectodermal component of the tumors, neuroblastic neoplasm...
12 KB (1,313 words) - 00:50, 20 February 2023
onset of myogenesis in the embryo. They discovered a population of Pax3/Pax7-positive progenitors that are essential for foetal muscle development and...
16 KB (1,578 words) - 08:52, 13 September 2024