Peroxisome biogenesis factor 1, also known as PEX1, is a protein which in humans is encoded by the PEX1 gene. This gene encodes a member of the AAA protein...
11 KB (1,212 words) - 07:43, 4 January 2024
and InterPro: IPR006052 Tumor+Necrosis+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) pex1 tumor necrosis factor gene...
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loss, and retinopathy. PBD-ZSD is most commonly caused by mutations in the PEX1, PEX6, PEX10, PEX12, and PEX26 genes. This results in the over-accumulation...
8 KB (578 words) - 19:15, 22 July 2024
This condition is caused by mutations in peroxisomal biogenesis factor 1 (PEX1) or peroxisomal biogenesis factor 6 (PEX6) genes. These gene are involved...
3 KB (317 words) - 20:01, 14 September 2023
with PEX1 and is recruited to the membrane by PEX26. From yeast to plants to humans, there is only one verified function of PEX6; PEX6 (and PEX1) removes...
11 KB (1,393 words) - 23:03, 28 January 2023
normal assembly of peroxisomes. Most commonly, patients have mutations in the PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, or PEX26...
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000 males XYYYY syndrome (49,XYYYY) Y 1:1,000,000 males Zellweger syndrome PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, PEX26...
42 KB (983 words) - 10:34, 21 August 2024
single-pass transmembrane proteins, for example Peroxisomal biogenesis factor 11. PEX1 PEX2 PEX3 PEX5 PEX6 PEX7 PEX10 PEX11A, PEX11B, PEX11G PEX12 PEX13 PEX14 PEX16...
2 KB (133 words) - 18:24, 25 December 2023
organelle are regulated by Pex11p. Genes that encode peroxin proteins include: PEX1, PEX2 (PXMP3), PEX3, PEX5, PEX6, PEX7, PEX9, PEX10, PEX11A, PEX11B, PEX11G...
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followed by an ATP dependent removal involving the cytosolic protein complex pex1 and pex6. The cycle for pex5 mediated import into the peroxisomal matrix...
52 KB (6,402 words) - 02:22, 14 August 2024
IQCA1; KATNA1; KATNAL1; KATNAL2; LONP1; LONP2; MDN1; NSF; NVL; ORC1; ORC4; PEX1; PEX6; PSMC1; PSMC2 (Nbla10058); PSMC3; PSMC4; PSMC5; PSMC6; RFC1; RFC2;...
12 KB (1,352 words) - 14:58, 30 July 2024
O00541 11964 PET100 HGNC:40038 P0DJ07 11965 PET117 HGNC:40045 Q6UWS5 11966 PEX1 HGNC:8850 O43933 11967 PEX2 HGNC:9717 P28328 11968 PEX3 HGNC:8858 P56589...
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PMID 9521874. Collins CS, Gould SJ (1999). "Identification of a common PEX1 mutation in Zellweger syndrome". Hum. Mutat. 14 (1): 45–53. doi:10...
12 KB (1,464 words) - 07:55, 30 January 2023
T, Kondo N, Osumi T, Fujiki Y (1998). "Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders". Hum. Mol. Genet...
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normal peroxisome assembly. Most commonly, patients have mutations in the PEX1, PEX3, PEX6, PEX12, and PEX26 genes. In almost all cases, patients have mutations...
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Adrenoleukodystrophy; 300100; ABCD1 Adrenoleukodystrophy, neonatal; 202370; PEX1 Adrenoleukodystrophy, neonatal; 202370; PEX10 Adrenoleukodystrophy, neonatal;...
234 KB (18,877 words) - 15:43, 9 May 2024
humans is encoded by the PEX26 gene. PEX26 has been shown to interact with PEX1, PEX6 and SUFU. GRCh38: Ensembl release 89: ENSG00000215193 – Ensembl, May...
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JC, Ameritunga R, Moser HW, Valle D, Gould SJ (Dec 1997). "Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders". Nature Genetics...
12 KB (1,507 words) - 07:44, 4 January 2024