• Thumbnail for Phosphatidylinositol
    Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph...
    20 KB (2,015 words) - 13:57, 6 September 2024
  • Thumbnail for Phosphoinositide 3-kinase
    Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth...
    32 KB (3,463 words) - 17:34, 20 November 2023
  • Phosphatidylinositol-4-phosphate 5-kinases (PIP5Ks, or PI4P5Ks) are a class of enzymes that phosphorylate phosphatidylinositol 4-phosphate. They perform...
    11 KB (1,239 words) - 21:04, 19 May 2024
  • Phosphatidylinositol phosphate may refer to: Phosphatidylinositol 3-phosphate, also known as PI(3)P Phosphatidylinositol 4-phosphate, also known as PI(4)P...
    276 bytes (64 words) - 16:21, 29 July 2011
  • Thumbnail for Kinase
    transmission. Phosphatidylinositol kinases phosphorylate phosphatidylinositol species, to create species such as phosphatidylinositol 3,4-bisphosphate...
    34 KB (3,807 words) - 07:35, 29 October 2024
  • Thumbnail for Phosphatidylinositol 4,5-bisphosphate
    Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P2, also known simply as PIP2 or PI(4,5)P2, is a minor phospholipid component of cell membranes. PtdIns(4...
    21 KB (2,099 words) - 13:43, 21 August 2024
  • Thumbnail for Phosphatidylinositol (3,4,5)-trisphosphate
    Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide 3-kinases' (PI 3-kinases)...
    8 KB (779 words) - 21:05, 19 May 2024
  • Thumbnail for Phosphatidylinositol 3-phosphate
    Phosphatidylinositol 3-phosphate (PI3P) is a phospholipid found in cell membranes that helps to recruit a range of proteins, many of which are involved...
    3 KB (274 words) - 16:20, 6 June 2024
  • Phosphatidylinositol-4-phosphate (PtdIns4P, PI-4-P, PI4P, or PIP) is a precursor of phosphatidylinositol (4,5)-bisphosphate. PtdIns4P is prevalent in the...
    3 KB (298 words) - 17:53, 6 March 2024
  • Thumbnail for PIGA
    Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIG-A, or phosphatidylinositol glycan, class A) is the catalytic subunit of the phosphatidylinositol...
    9 KB (1,106 words) - 20:03, 27 October 2023
  • Phosphatidylinositol phosphate kinases (PIPK) are kinases that phosphorylate the phosphoinositides PtdInsP and PtdInsP2 that are derivatives of phosphatidylinositol...
    3 KB (377 words) - 11:20, 23 November 2021
  • Phosphatidylinositol 3-kinase-related kinases (PIKKs) are a family of Ser/Thr-protein kinases with sequence similarity to phosphatidylinositol-3 kinases...
    2 KB (106 words) - 09:29, 23 October 2022
  • in a wide variety of biological processes. GPI is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine...
    6 KB (656 words) - 16:08, 10 July 2024
  • Thumbnail for Phosphatidylinositol transfer protein
    Phosphatidylinositol transfer protein (PITP) or priming in exocytosis protein 3 (PEP3) is a ubiquitous cytosolic domain involved in transport of phospholipids...
    4 KB (406 words) - 03:13, 29 November 2023
  • Thumbnail for 1-phosphatidylinositol 4-kinase
    In enzymology, a 1-phosphatidylinositol 4-kinase (EC 2.7.1.67) is an enzyme that catalyzes the chemical reaction ATP + 1-phosphatidyl-1D-myo-inositol ⇌...
    4 KB (366 words) - 16:31, 22 September 2024
  • Phosphatidylinositol 5-phosphate (PtdIns5P) is a phosphoinositide, one of the phosphorylated derivatives of phosphatidylinositol (PtdIns), that are well-established...
    23 KB (2,323 words) - 05:38, 17 June 2024
  • Thumbnail for Phospholipid
    Phosphoinositides: Phosphatidylinositol (PI) Phosphatidylinositol phosphate (PIP) Phosphatidylinositol bisphosphate (PIP2) and Phosphatidylinositol trisphosphate...
    24 KB (1,798 words) - 23:50, 30 October 2024
  • Thumbnail for Phosphatidylinositol 3,4-bisphosphate
    Phosphatidylinositol (3,4)-bisphosphate (PtdIns(3,4)P2) is a minor phospholipid component of cell membranes, yet an important second messenger. The generation...
    12 KB (1,702 words) - 21:59, 19 June 2024
  • The enzyme phosphatidylinositol deacylase (EC 3.1.1.52) catalyzes the reaction 1-phosphatidyl-D-myo-inositol + H2O ⇌ {\displaystyle \rightleftharpoons...
    2 KB (142 words) - 15:22, 26 August 2023
  • Thumbnail for Phosphatidylinositol 3,5-bisphosphate
    Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is one of the seven phosphoinositides found in eukaryotic cell membranes. In quiescent cells, the...
    18 KB (2,639 words) - 11:18, 21 October 2023
  • In enzymology, a phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) is an enzyme that catalyzes the chemical reaction in which at least one alpha-D-mannose...
    2 KB (139 words) - 18:17, 23 January 2024
  • The enzyme phosphatidylinositol-3-phosphatase (EC 3.1.3.64) catalyzes the reaction 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O ⇌ {\displaystyle \rightleftharpoons...
    2 KB (206 words) - 14:57, 22 September 2024
  • PIP2, or phosphatidylinositol biphosphate, is the products obtained by cleavage of PIP3, or by phosphorylation of PI(3)P, PI(4)P or PI(5)P. 'PIP2' most...
    674 bytes (100 words) - 02:26, 22 October 2018
  • Thumbnail for PLCB4
    1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 is an enzyme that in humans is encoded by the PLCB4 gene. The protein encoded by this...
    6 KB (737 words) - 10:51, 17 October 2022
  • Thumbnail for Phosphatidylinositol diacylglycerol-lyase
    The enzyme phosphatidylinositol diacylglycerol-lyase (EC 4.6.1.13) catalyzes the following reaction: 1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1...
    4 KB (339 words) - 06:26, 23 September 2024
  • Thumbnail for Inositol
    component of the structural lipids phosphatidylinositol (PI) and its various phosphates, the phosphatidylinositol phosphate (PIP) lipids. In humans, myo-Inositol...
    38 KB (4,040 words) - 22:00, 12 October 2024
  • Thumbnail for Insulin receptor substrate 1
    adenocarcinomas. Ablation of IRS-1 alters downstream signalling through phosphatidylinositol-3 kinase (PI3K), causing an increased interaction of it with platelet-derived...
    34 KB (4,304 words) - 07:20, 3 September 2024
  • Thumbnail for GSDMD
    interact with: Phosphatidylinositol 4-phosphate Phosphatidylinositol (4,5)-bisphosphate Phosphatidylinositol 3-phosphate Phosphatidylinositol 5-phosphate...
    14 KB (1,765 words) - 11:02, 28 March 2024
  • Thumbnail for PLCE1
    a phospholipase enzyme (PLCE1) that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4...
    15 KB (1,740 words) - 06:00, 24 December 2023
  • Thumbnail for Lecithin
    glycerophospholipids including phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, and phosphatidic acid. Lecithin was first isolated...
    26 KB (2,626 words) - 20:30, 7 November 2024