• Prorenin (/prəˈriːnɪn/) is a protein that constitutes a precursor for renin, the hormone that activates the renin–angiotensin system, which serves to raise...
    6 KB (631 words) - 08:07, 11 March 2024
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    receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor (see also below), as well as enzymatic activity with which it...
    18 KB (2,105 words) - 05:11, 13 November 2024
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    is reduced, juxtaglomerular cells in the kidneys convert the precursor prorenin (already present in the blood) into renin and secrete it directly into...
    22 KB (2,510 words) - 04:31, 10 September 2024
  • 119, KLK13, kallikrein mK13, mGK-13, mK13, mKLK13, prorenin converting enzyme 1, PRECE-1, prorenin-converting enzyme, PRECE, proteinase P) is an enzyme...
    2 KB (270 words) - 14:38, 26 August 2023
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    protein 2, or the prorenin receptor, is a protein that in humans is encoded by the ATP6AP2 gene. The renin receptor binds renin and prorenin. Binding of renin...
    7 KB (811 words) - 03:46, 23 June 2024
  • laboratory where Eugenie Lumbers had just found early clues to the existence of prorenin (the protein precursor of renin) during her PhD work. He remained interested...
    9 KB (701 words) - 21:33, 28 December 2023
  • analysis of cDNA for human renin precursor. PubMed. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin....
    8 KB (763 words) - 01:24, 25 December 2022
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    Gahnem F, Halimi JM, Laragh JH (1991). "The greater renin system. Its prorenin-directed vasodilator limb. Relevance to diabetes mellitus, pregnancy, and...
    10 KB (945 words) - 20:18, 5 December 2024
  • recognized by the juxtaglomerular (JG) cells and promotes the cleavage of prorenin into renin. Each kidney is surrounded by two layers of connective tissue...
    10 KB (1,114 words) - 03:20, 24 December 2024
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    PC4, PC5/6, PC7/8, PCSK9, and SKI1/S1P. Proprotein convertase 1 converts prorenin into renin. Variants in the PCSK1 gene may be associated with obesity....
    5 KB (600 words) - 15:33, 26 August 2023
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    apparatus, which is the only source of active renin, although its precursor, prorenin, can be secreted by other tissues, such as the salivary glands, brain,...
    45 KB (4,784 words) - 20:59, 24 November 2024
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    processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160...
    8 KB (1,065 words) - 17:37, 21 May 2024
  • professor at University of Newcastle. Along with Brian Morris she discovered prorenin, (the protein precursor of renin); her initial findings were met with disbelief...
    6 KB (544 words) - 17:36, 14 November 2024
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    role in tumor growth of Ewing sarcoma. A new role of Sox6 in renin and prorenin regulation was studied using a Sox KO mouse model in which Sox6 is only...
    10 KB (1,178 words) - 16:31, 22 August 2024
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    genomic sequence and association of an intronic T/C polymorphism with the prorenin level in males". Hum. Mol. Genet. 6 (9): 1527–34. doi:10.1093/hmg/6.9.1527...
    7 KB (895 words) - 23:07, 4 September 2022