A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides...
26 KB (2,799 words) - 15:02, 30 June 2024
Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's)...
22 KB (2,339 words) - 16:14, 25 June 2024
Catalytic triad (redirect from N-terminal nucleophilic protease)
triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An acid-base-nucleophile...
57 KB (5,790 words) - 20:33, 13 May 2024
Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...
250 bytes (55 words) - 20:49, 9 June 2020
and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic...
12 KB (838 words) - 10:11, 12 August 2024
Cysteine proteases, also known as thiol proteases, are hydrolase enzymes that degrade proteins. These proteases share a common catalytic mechanism that...
14 KB (1,278 words) - 22:29, 25 April 2024
Protease A may refer to one of two enzymes: Streptogrisin A Omptin This disambiguation page lists articles associated with the title Protease A. If an...
95 bytes (44 words) - 19:59, 29 December 2019
three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites). The native TEV protease also...
16 KB (1,866 words) - 02:28, 14 August 2024
3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...
17 KB (1,651 words) - 07:02, 9 July 2024
Prion (redirect from Protease-resistant PrP)
found in infectious prions has a different structure and is resistant to proteases, the enzymes in the body that can normally break down proteins. The normal...
106 KB (11,481 words) - 20:06, 25 August 2024
In molecular biology, the Lon protease family is a family of enzymes that break peptide bonds in proteins resulting in smaller peptides or amino acids...
4 KB (397 words) - 12:40, 9 July 2023
Proteinase K (redirect from Protease K)
In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase,...
10 KB (1,063 words) - 00:29, 20 June 2024
Variably protease-sensitive prionopathy (VPSPr) (formerly known as Protease Sensitive Prionopathy) is a sporadic prion protein disease first described...
9 KB (910 words) - 13:01, 24 January 2024
Intramembrane proteases (IMPs), also known as intramembrane-cleaving proteases (I-CLiPs), are enzymes that have the property of cleaving transmembrane...
12 KB (1,287 words) - 18:56, 26 April 2024
two classes of acidic proteases: Aspartic proteases - that use a catalytic aspartic acid in their active site Glutamic proteases - that use a catalytic...
244 bytes (65 words) - 21:07, 9 March 2016
Picornain 2A (redirect from Poliovirus protease 2A)
picornavirus endopeptidase 2A, poliovirus protease 2A, rhinovirus protease 2A, 2A protease, 2A proteinase, protease 2A, proteinase 2Apro, picornaviral 2A...
2 KB (198 words) - 15:28, 26 August 2023
sixth catalytic type of protease. Members of this group of protease had been previously assumed to be an aspartate protease, but structural determination...
8 KB (857 words) - 02:12, 14 August 2024
Proteases (also sometimes referred to as proteolytic enzymes or peptidases) are in use, or have been proposed or tried, for a number of purposes related...
12 KB (1,339 words) - 16:56, 29 June 2023
Threonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class...
5 KB (434 words) - 22:58, 25 April 2024
Serpin (redirect from Serine protease inhibitors)
proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym...
137 KB (14,301 words) - 09:55, 15 August 2024
Nirmatrelvir (category SARS-CoV-2 main protease inhibitors)
medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of a nirmatrelvir/ritonavir combination used to treat...
25 KB (2,022 words) - 16:13, 18 June 2024
The rhomboid proteases are a family of enzymes that exist in almost all species. They are proteases: they cut the polypeptide chain of other proteins....
42 KB (4,629 words) - 01:58, 16 December 2023
Actinidain (redirect from Actinidia anionic protease)
22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit...
16 KB (1,922 words) - 15:42, 27 November 2023
HIV-1 protease or PR is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential...
20 KB (2,197 words) - 00:57, 13 January 2024
ADAMTS13 (redirect from Von Willebrand factor-cleaving protease)
type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand...
12 KB (1,420 words) - 09:40, 14 January 2024
ligands, like protease inhibitors, that can modulate catalytic activities has an enormous therapeutic effect. Hence, inhibition of the HIV protease is one of...
33 KB (4,117 words) - 22:23, 23 August 2022
(HIV protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor)...
4 KB (260 words) - 16:19, 11 August 2024
In biology and biochemistry, protease inhibitors, or antiproteases, are molecules that inhibit the function of proteases (enzymes that aid the breakdown...
19 KB (1,811 words) - 01:19, 29 November 2023
Picornain 3C (redirect from Poliovirus protease 3C)
Picornain 3C (EC 3.4.22.28) is a protease found in picornaviruses, which cleaves peptide bonds of non-terminal sequences. Picornain 3C’s endopeptidase...
19 KB (2,412 words) - 14:53, 29 September 2023
Protease VII may refer to: Omptin Caspase 1 This disambiguation page lists articles associated with the title Protease VII. If an internal link led you...
72 bytes (40 words) - 19:59, 29 December 2019