• Thumbnail for Pyrrolysine
    Pyrrolysine (symbol Pyl or O; encoded by the 'amber' stop codon UAG) is an α-amino acid that is used in the biosynthesis of proteins in some methanogenic...
    21 KB (2,273 words) - 23:26, 10 November 2024
  • Thumbnail for Amino acid
    similar cysteine, and participates in several unique enzymatic reactions. Pyrrolysine (Pyl, O) is another amino acid not encoded in DNA, but synthesized into...
    98 KB (10,151 words) - 03:53, 21 October 2024
  • Thumbnail for Proteinogenic amino acid
    in the standard genetic code and an additional 2 (selenocysteine and pyrrolysine) that can be incorporated by special translation mechanisms. In contrast...
    38 KB (1,631 words) - 14:51, 30 August 2024
  • glutamic acid, serine, and selenocysteine (considered the 21st amino acid). Pyrrolysine (considered the 22nd amino acid), which is proteinogenic only in certain...
    27 KB (2,690 words) - 10:20, 3 September 2024
  • Thumbnail for Genetic code
    code for pyrrolysine. Selenocysteine came to be seen as the 21st amino acid, and pyrrolysine as the 22nd. Both selenocysteine and pyrrolysine may be present...
    73 KB (8,048 words) - 16:22, 21 November 2024
  • Pyrrolysine—tRNAPyl ligase (EC 6.1.1.26, PylS, pyrrolysyl-tRNA synthetase) is an enzyme with systematic name L-pyrrolysine:tRNAPyl ligase (AMP-forming)...
    2 KB (205 words) - 15:39, 26 August 2023
  • Look up pyl in Wiktionary, the free dictionary. Pyrrolysine, or Pyl, is a naturally occurring, genetically coded amino acid. Pyl or PYL may also refer...
    446 bytes (94 words) - 09:14, 4 September 2023
  • can expand its genetic code from 20 to 21 amino acids (by including pyrrolysine) under different conditions of growth. Strain Z-7288T (= DSM 5501 = ATCC...
    2 KB (127 words) - 22:41, 16 November 2024
  • Thumbnail for Non-proteinogenic amino acids
    However, there are two extra proteinogenic amino acids: selenocysteine and pyrrolysine. These non-standard amino acids do not have a dedicated codon, but are...
    27 KB (2,864 words) - 19:08, 10 October 2024
  • Thumbnail for 3-Methylornithine
    lysine and 3-methylornithine, also mediated enzymatically, produces pyrrolysine, which, for some organisms, is a 22nd genetically coded amino acid. Ornithine...
    2 KB (138 words) - 18:33, 16 November 2024
  • beta-lactam antibiotic MTSL, a chemical used for certain NMR experiments Pyrrolysine, an unusual proteinogenic amino acid 1-Pyrroline-5-carboxylic acid, a...
    2 KB (180 words) - 18:11, 27 August 2023
  • Thumbnail for Protein
    organisms the genetic code can include selenocysteine and—in certain archaea—pyrrolysine. Shortly after or even during synthesis, the residues in a protein are...
    103 KB (11,472 words) - 16:37, 31 October 2024
  • Histidine I Isoleucine K Lysine L Leucine M Methionine N Asparagine O Pyrrolysine P Proline Q Glutamine R Arginine S Serine T Threonine U Selenocysteine...
    56 KB (2,544 words) - 19:43, 15 November 2024
  • Putrescine Pyrethrin Pyridoxine or pyridoxamine (Vitamin B6) Pyrimidine Pyrrolysine Pyruvic acid Quinidine Quinine Quinone Radicicol Raffinose Relaxin Renin...
    12 KB (933 words) - 20:02, 10 May 2023
  • Thumbnail for Chargaff's rules
    in proteins. (There are two uncommon amino acids—selenocysteine and pyrrolysine—found in a limited number of proteins and encoded by the stop codons—TGA...
    19 KB (2,014 words) - 05:04, 2 November 2024
  • Thumbnail for Miller–Urey experiment
    Yes Ethionine No Cysteine Yes Histidine Yes Lysine Yes Asparagine Yes Pyrrolysine Yes Proline Yes Glutamine Yes Arginine Yes Threonine Yes Selenocysteine...
    70 KB (7,004 words) - 20:33, 31 October 2024
  • Thumbnail for Auxotrophy
    canonical twenty; two additional canonical amino acids (selenocysteine, pyrrolysine) are inserted into proteins by recoding translation termination signals...
    15 KB (1,872 words) - 18:01, 28 October 2024
  • Thumbnail for Biomolecule
    incorporated into some proteins at a UGA codon, which is normally a stop codon. Pyrrolysine is incorporated into some proteins at a UAG codon. For instance, in some...
    21 KB (2,381 words) - 00:12, 15 October 2024
  • Thumbnail for Selenocysteine
    spin of ⁠1/2⁠ and can be used for high-resolution NMR, among others. Pyrrolysine, another amino acid not in the basic set of 20. Selenomethionine, another...
    19 KB (1,975 words) - 14:39, 4 October 2024
  • Thumbnail for Methanosarcina
    animal digestive tracts. Methanosarcina grow in colonies. The amino acid pyrrolysine was first discovered in a Methanosarcina species, M. barkeri. Primitive...
    26 KB (2,456 words) - 23:30, 22 September 2024
  • Isoleucine (I) K Lysine L Leucine M Methionine/Start codon N Asparagine O Pyrrolysine (rare) P Proline Q Glutamine R Arginine S Serine T Threonine U Selenocysteine...
    25 KB (2,148 words) - 21:51, 26 October 2024
  • Thumbnail for Protein primary structure
    Leu L Lysine Lys K Methionine Met M Phenylalanine Phe F Proline Pro P Pyrrolysine Pyl O Selenocysteine Sec U Serine Ser S Threonine Thr T Tryptophan Trp...
    21 KB (2,599 words) - 01:04, 11 November 2024
  • Thumbnail for PYLIS downstream sequence
    In biology, the PYLIS downstream sequence (PYLIS: pyrrolysine insertion sequence) is a stem-loop structure that appears on some mRNA sequences. This structural...
    3 KB (319 words) - 10:15, 3 December 2023
  • Thumbnail for Stop codon
    have been run for other organisms. The UAG codon can translate into pyrrolysine (Pyl) in a similar manner. Distribution of stop codons within the genome...
    30 KB (2,821 words) - 22:41, 9 November 2024
  • 2011). "The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine". Nature. 471 (7340): 647–50. Bibcode:2011Natur.471..647G...
    1 KB (140 words) - 14:57, 26 August 2023
  • Thumbnail for Methanosarcinaceae
    this enzyme, and anywhere else pyrrolysine is incorporated, likely through contextual markers on the mRNA, the pyrrolysine-loaded tRNA is inserted instead...
    8 KB (547 words) - 21:23, 23 July 2024
  • Leu – leucine M or Met – methionine N or Asn – asparagine O or Pyl – pyrrolysine P or Pro – proline Q or Gln – glutamine R or Arg – arginine S or Ser...
    19 KB (13 words) - 04:46, 18 October 2024
  • Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine". BMC Genomics. 15 (1): 679. doi:10.1186/1471-2164-15-679. ISSN 1471-2164...
    66 KB (7,450 words) - 17:37, 18 November 2024
  • universal donor Haplogroup O (Y-DNA), a Y-chromosomal DNA haplogroup O, for pyrrolysine an alpha amino acid in biochemistry Class O, stellar classification for...
    6 KB (771 words) - 20:30, 31 October 2024
  • PMID 9006042. Krzycki JA (October 2004). "Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases". Current Opinion...
    2 KB (156 words) - 16:05, 26 August 2023