Ring finger protein 43 is a protein that in humans is encoded by the RNF43 gene. The protein encoded by this gene is a RING-type E3 ubiquitin ligase and...
6 KB (801 words) - 15:29, 25 June 2024
Beneteau, Claire; de Sousa, Sergio B. (May 2018). "RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6". Nature. 557...
7 KB (631 words) - 10:02, 21 November 2024
lower risk. While the only validated genetic cause of SPS is mutations in RNF43, additional important genetic abnormalities include BRAF mutations, abnormal...
23 KB (2,577 words) - 16:49, 25 June 2024
R-spondin complex acts by binding and subsequently internalizing RNF43 and ZNRF3. RNF43 and ZNRF3 are transmembrane E3 ligases that negatively regulate...
21 KB (2,708 words) - 13:28, 14 August 2023
Q9H2S5 13859 RNF40 HGNC:16867 O75150 13860 RNF41 HGNC:18401 Q9H4P4 13861 RNF43 HGNC:18505 Q68DV7 13862 RNF44 HGNC:19180 Q7L0R7 13863 RNF103 HGNC:12859...
282 KB (17 words) - 08:00, 19 November 2024
have been associated with polyposis, such as GREM1, MSH3, MLH3, NTHL1, RNF43 and RPS20. Familial adenomatous polyposis (FAP) is a form of hereditary...
30 KB (2,858 words) - 07:50, 6 April 2024
KRAS gene mutations (40–65% of cases) and in the GNAS Gs alpha subunit and RNF43, affecting the Wnt signaling pathway. Even if removed surgically, a considerably...
122 KB (12,842 words) - 09:00, 11 November 2024
carry activating mutations in beta catenin or inactivating mutations in RNF43. Mutations in APC can be inherited, or arise sporadically in the somatic...
28 KB (3,225 words) - 01:48, 6 May 2024
RNF19A, RNF20, RNF24, RNF25, RNF26, RNF32, RNF38, RNF39, RNF40, RNF41, RNF43, RNF44, RNF55, RNF71, RNF103, RNF111, RNF113A, RNF113B, RNF121, RNF122,...
12 KB (1,259 words) - 10:55, 10 September 2024
with: APC, CTNNB1, CSNK1E, CSNK1A1, DVL1, GSK3B, LRP5, MAP3K1, PPP2R5A, RNF43, and TSC2. GRCh38: Ensembl release 89: ENSG00000103126 – Ensembl, May 2017...
17 KB (2,001 words) - 05:24, 30 September 2024
Bosso-Lefèvre C, Khatoo M, Thi Tran H, et al. (May 2018). "RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6". Nature. 557...
4 KB (417 words) - 05:12, 22 June 2023
Tsukiyama T, Sho T, Okumura F, Asaka M, Hatakeyama S (January 2011). "RNF43 interacts with NEDL1 and regulates p53-mediated transcription". Biochemical...
5 KB (612 words) - 02:05, 1 December 2023
as PIK3CA, IDH1, IDH2, ARID1A, ARID2, ATRX, DAXX, MLL2, MLL3, CIC, and RNF43. Vogelstein pioneered the idea that somatic mutations represent uniquely...
41 KB (3,823 words) - 08:46, 30 August 2024
Altunoglu, Umut; Leushacke, Marc; et al. (2018-05-16). "RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6". Nature. 557...
50 KB (4,290 words) - 11:22, 3 December 2024