• Rab family of proteins is a member of the Ras superfamily of small G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab...
    12 KB (1,327 words) - 12:48, 10 May 2024
  • Thumbnail for Prenylation
    the Rab geranylgeranyl transferase can recognize. The Rab proteins usually terminate in a CC or CXC motif. Instead, Rab proteins are bound by the Rab escort...
    15 KB (1,810 words) - 16:46, 26 June 2024
  • Look up rab or Rab in Wiktionary, the free dictionary. Rab may refer to: Rab (island), an island in Croatia Rab (town), on the island of Rab Ráb, the Slovak...
    2 KB (256 words) - 12:18, 3 February 2024
  • Thumbnail for Rab escort protein 1
    Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene....
    10 KB (1,240 words) - 21:32, 13 August 2023
  • Thumbnail for Vesicle (biology and chemistry)
    humans. Regulatory Rab proteins are thought to inspect the joining of the SNAREs. Rab protein is a regulatory GTP-binding protein and controls the binding...
    36 KB (3,649 words) - 05:36, 29 June 2024
  • Thumbnail for Rab geranylgeranyltransferase
    Rab geranylgeranyltransferase also known as (protein) geranylgeranyltransferase II is one of the three prenyltransferases. It transfers (usually) two geranylgeranyl...
    8 KB (858 words) - 00:39, 3 December 2023
  • TBC1D4, allowing for Rab protein to change from its GDP to GTP bound state. Inhibition of the GTPase-activating domain leaves proteins next in the cascade...
    25 KB (2,937 words) - 17:58, 15 January 2024
  • Thumbnail for TBC1D30
    TBC1D30 (section Protein)
    that encodes the protein of the same name. This protein has two domains, one of which is involved in the processing of the Rab protein. Much of the function...
    17 KB (1,160 words) - 14:06, 7 December 2023
  • Thumbnail for RAB4B
    Ras-related protein Rab-4B is a protein that in humans is encoded by the RAB4B gene. Ras-related protein Rab-4B is involved in the vesicle recycling process...
    9 KB (1,093 words) - 10:51, 13 May 2024
  • Thumbnail for GDI1
    Rab GDP dissociation inhibitor alpha is a protein that in humans is encoded by the GDI1 gene. GDP dissociation inhibitors are proteins that regulate the...
    9 KB (1,241 words) - 22:28, 13 December 2023
  • Thumbnail for Choroideremia
    mutation in the CHM gene which encodes Rab escort protein 1 (REP1), a protein involved in lipid modification of Rab proteins. While the complete mechanism of...
    28 KB (3,087 words) - 11:46, 26 August 2023
  • Thumbnail for RAB2B
    RAB2B (category G proteins)
    Ras-related protein Rab-2B is a protein that in humans is encoded by the RAB2B gene. RAB2B is required for protein transport from the endoplasmic reticulum...
    7 KB (981 words) - 19:53, 3 March 2023
  • Thumbnail for RAB5A
    Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene. RAB5A localizes to early endosomes where it is involved in the recruitment...
    12 KB (1,473 words) - 18:12, 20 July 2024
  • Thumbnail for RAB39B
    Ras-related protein Rab-39B is a protein that in humans is encoded by the RAB39B gene. This gene encodes a member of the Rab family of proteins. Rab proteins are...
    4 KB (464 words) - 23:24, 4 September 2022
  • Thumbnail for RAB1B
    Ras-related protein Rab-1B is a protein that in humans is encoded by the RAB1B gene. RAB1B has been shown to interact with GOLGA2. GRCh38: Ensembl release...
    7 KB (893 words) - 00:40, 3 December 2023
  • Thumbnail for Guanosine nucleotide dissociation inhibitor
    escort protein (REP)-1. REP-1 presents newly synthesised Rab proteins to the catalytic component, and forms a stable complex with the prenylated proteins following...
    5 KB (550 words) - 04:51, 11 December 2020
  • Thumbnail for RAB10
    Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 has been shown to interact with AP1S1. GRCh38: Ensembl release...
    4 KB (539 words) - 12:30, 10 December 2023
  • Thumbnail for Vesicular transport protein
    Caveolin Dynamin and related proteins, such as the EHD protein family Rab proteins SNAREs Vesicular transport adaptor proteins e.g. Sorting nexins Synaptotagmin...
    2 KB (170 words) - 18:17, 14 February 2022
  • Thumbnail for RAB2A
    Ras-related protein Rab-2A is a protein that in humans is encoded by the RAB2A gene. Members of the Rab protein family are nontransforming monomeric GTP-binding...
    8 KB (994 words) - 08:34, 13 August 2023
  • Thumbnail for RAB37
    Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene. Rab proteins are low molecular mass GTPases that are critical regulators...
    4 KB (434 words) - 21:09, 13 October 2022
  • Thumbnail for RAB8A
    Ras-related protein Rab-8A is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily...
    9 KB (1,100 words) - 23:02, 10 April 2024
  • Thumbnail for RAB7A
    Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. Ras-related protein Rab-7a is involved in endocytosis, which is a...
    18 KB (2,315 words) - 05:30, 27 May 2024
  • Thumbnail for CHML (gene)
    Rab proteins geranylgeranyltransferase component A 2 is an enzyme that in humans is encoded by the CHML gene. The product of the CHML gene supports geranylgeranylation...
    7 KB (753 words) - 13:57, 11 October 2022
  • Thumbnail for RAB4A
    RAB4A (category Protein stubs)
    Ras-related protein Rab-4A is a protein that in humans is encoded by the RAB4A gene. RAB4A has been shown to interact with: CD2AP, KIF3B, RAB11FIP1, RABEP1...
    10 KB (1,214 words) - 22:56, 10 April 2024
  • Thumbnail for RAB27A
    Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily...
    13 KB (1,563 words) - 11:44, 14 January 2024
  • Thumbnail for GDI2
    Rab GDP dissociation inhibitor beta is a protein that in humans is encoded by the GDI2 gene. GDP dissociation inhibitors are proteins that regulate the...
    7 KB (928 words) - 15:43, 10 June 2024
  • Thumbnail for TBC1D4
    family member 4 (TBC1D4), is a Rab GTPase-activating protein that in humans is encoded by the TBC1D4 gene. The 160 kD protein product was first discovered...
    11 KB (1,368 words) - 01:33, 4 March 2023
  • Thumbnail for RAB11B
    RAB11B (category G proteins)
    Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. Rab11b is reported as most abundantly expressed in brain, heart...
    21 KB (2,350 words) - 07:38, 5 January 2024
  • Thumbnail for RAB3A
    Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. It is involved in calcium-triggered exocytosis in neurons. RAB3A...
    11 KB (1,256 words) - 22:30, 22 December 2023
  • Thumbnail for Endoplasmic reticulum
    peptide. Integral membrane proteins that stay embedded in the membrane as vesicles exit and bind to new membranes. Rab proteins are key in targeting the...
    34 KB (3,710 words) - 08:29, 7 July 2024