• Thumbnail for SMURF1
    E3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene. The SMURF1 Gene encodes a protein with a size of 757 amino...
    16 KB (1,916 words) - 16:38, 23 March 2024
  • of service (DoS) attack on computer networks SMURF1, an enzyme that in humans is encoded by the SMURF1 gene SMURF2, an enzyme that in humans is encoded...
    3 KB (366 words) - 03:16, 11 April 2024
  • membrane Slingshot homolog Slit-Robo and the associated Netrin-Frazzled SMURF1 and SMURF2, which interacts with Mothers against decapentaplegic 7 SMAD...
    13 KB (795 words) - 18:00, 13 June 2024
  • downstream targets of TGFβ signaling. The E3 ubiquitin-protein ligases SMURF1 and SMURF2 regulate the levels of SMADs. They accept ubiquitin from an E2...
    20 KB (2,098 words) - 00:36, 28 November 2023
  • Thumbnail for Ubiquitin ligase
    NEDD4, NEDD4L PPIL2 PRPF19 PIAS1, PIAS2, PIAS3, PIAS4 RANBP2 RNF4 RBX1 SMURF1, SMURF2 STUB1 TOPORS TRIP12 UBE3A, UBE3B, UBE3C, UBE3D UBE4A, UBE4B UBOX5...
    24 KB (2,754 words) - 03:25, 27 May 2024
  • ligase complex and affects the ubiquitination and proteasomal degradation of SMURF1, which regulates the BMP pathway. "jet jetlag [Drosophila melanogaster (fruit...
    13 KB (1,496 words) - 09:53, 31 July 2024
  • Q2TAL5 15385 SMU1 HGNC:18247 Q2TAY7 15386 SMUG1 HGNC:17148 Q53HV7 15387 SMURF1 HGNC:16807 Q9HCE7 15388 SMURF2 HGNC:16809 Q9HAU4 15389 SMYD1 HGNC:20986...
    242 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for NEDD4
    members: NEDD4 (the core topic of this article) NEDD4-2 (or NEDD4L) ITCH SMURF1 SMURF2 WWP1 WWP2 NEDL1 (HECW1) NEDDL2 (HECW2)]. NEDD4 regulates a large...
    27 KB (3,414 words) - 21:44, 27 March 2024
  • Thumbnail for Mothers against decapentaplegic homolog 1
    This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation...
    4 KB (468 words) - 04:01, 25 March 2022
  • Thumbnail for PLEKHO1
    gene. PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1 and SMURF1. GRCh38: Ensembl release 89: ENSG00000023902 – Ensembl, May 2017 GRCm38:...
    7 KB (918 words) - 16:58, 11 October 2022
  • Thumbnail for Mothers against decapentaplegic homolog 6
    Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K (2001). "Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7...
    11 KB (1,283 words) - 06:30, 11 December 2023
  • Thumbnail for HECW2
    BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1". The EMBO Journal. 30 (13): 2675–89. doi:10.1038/emboj.2011.155. PMC 3155294...
    2 KB (281 words) - 16:27, 28 November 2023
  • Thumbnail for ARHGEF9
    signaling.[supplied by OMIM] ARHGEF9 has been shown to interact with GPHN and SMURF1. GRCh38: Ensembl release 89: ENSG00000131089 – Ensembl, May 2017 GRCm38:...
    4 KB (510 words) - 00:17, 28 July 2024
  • contractility, and protein synthesis Biogrid, InnateDB, Mentha SMAD ubiquitin regulatory factor 1 (SMURF1) E3 ubiquitin-protein ligase Biogrid, Mentha...
    13 KB (925 words) - 03:07, 10 March 2024
  • Thumbnail for NDFIP1
    negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation". J. Immunol. 189 (11): 5304–13. doi:10.4049/jimmunol...
    4 KB (573 words) - 09:50, 17 October 2022
  • Thumbnail for C2 domain
    RASAL2; RGS3; RIMS1; RIMS2; RIMS3; RIMS4; RPGRIP1; RPGRIP1L; RPH3A; SGA72M; SMURF1; SMURF2; SYNGAP1; SYT1; SYT10; SYT11; SYT12; SYT13; SYT14; SYT14L; SYT15;...
    11 KB (1,059 words) - 16:49, 31 July 2024
  • Thumbnail for KLF15
    KLF15 upregulates the expression of the E3 ubiquitin ligases atrogin-1 and SMuRF1 genes and negatively modulates myofiber size. Two kidney-specific CLC chloride...
    21 KB (2,804 words) - 04:27, 26 February 2024
  • Thumbnail for PDLIM7
    bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads". The Journal of Biological...
    7 KB (759 words) - 11:04, 18 August 2023
  • Thumbnail for SMURF2
    decapentaplegic homolog 3, Mothers against decapentaplegic homolog 7, SCYE1, SMURF1, and Ubiquitin C. TOP2A, GRCh38: Ensembl release 89: ENSG00000108854 – Ensembl...
    11 KB (1,326 words) - 10:53, 5 December 2023
  • Thumbnail for HECW1
    BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1". The EMBO Journal. 30 (13): 2675–89. doi:10.1038/emboj.2011.155. PMC 3155294...
    5 KB (612 words) - 02:05, 1 December 2023
  • Thumbnail for Mothers against decapentaplegic homolog 7
    M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K (April 2001). "Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7...
    23 KB (2,866 words) - 16:28, 22 August 2024