• Thumbnail for SOX4
    Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box)...
    11 KB (1,173 words) - 15:04, 2 November 2024
  • Thumbnail for SOX12
    Sox4 and Sox11. Sox12-null knockout mice appear normal, unlike Sox4 or Sox11 knockout mice. This probably comes from functional redundancy with Sox4 and...
    4 KB (490 words) - 20:01, 13 June 2022
  • Thumbnail for Mir-129 microRNA precursor family
    miR-129 and the over-expression of SOX4. In experiments where miR-129 levels were returned to normal in cancer cells, SOX4 expression was down regulated....
    13 KB (1,700 words) - 11:28, 2 November 2024
  • Thumbnail for Coffin–Siris syndrome
    including SOX11, ARID2, DPF2, PHF6, SMARCA2, SMARCA4, SMARCB1, SMARCC2, SMARCE1, SOX4. The diagnosis is generally based on the presence of major and at least one...
    8 KB (717 words) - 04:44, 6 August 2024
  • most other vertebrates have three members of the SoxC group. The three are Sox4, Sox11, and Sox12. These three are extremely similar to one another, more...
    5 KB (591 words) - 16:00, 6 June 2023
  • ENSG00000039600 HMG/Sox Known motif – High-throughput in vitro [853] RACAAT SOX4 ENSG00000124766 HMG/Sox Known motif – High-throughput in vitro [854] AACAAWGR...
    374 KB (81 words) - 02:10, 23 September 2023
  • Thumbnail for SOX15
    1998). "Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and...
    5 KB (586 words) - 15:04, 2 November 2024
  • Thumbnail for Tubulin beta-3 chain
    translational levels. In neural tissue, constitutive expression is driven by Sox4 and Sox11. In non-neural tissues, regulation is dependent on an E-box site...
    26 KB (3,140 words) - 20:34, 10 July 2024
  • HGNC:11189 O00570 15513 SOX2 HGNC:11195 P48431 15514 SOX3 HGNC:11199 P41225 15515 SOX4 HGNC:11200 Q06945 15516 SOX5 HGNC:11201 P35711 15517 SOX6 HGNC:16421 P35712...
    242 KB (17 words) - 18:43, 6 October 2024
  • groups are: SoxA: SRY SoxB1: SOX1, SOX2, SOX3 SoxB2: SOX14, SOX21 SoxC: SOX4, SOX11, SOX12 SoxD: SOX5, SOX6, SOX13 SoxE: SOX8, SOX9, SOX10 SoxF: SOX7...
    6 KB (715 words) - 06:15, 3 June 2024
  • possible Sox family member to participate in gene regulation with Oct4 – Sox4, Sox11, and Sox15 also participate, as the Sox protein is redundant throughout...
    49 KB (5,387 words) - 17:07, 6 April 2024
  • Thumbnail for SOX11
    J (Dec 2006). "The establishment of neuronal properties is controlled by Sox4 and Sox11". Genes & Development. 20 (24): 3475–86. doi:10.1101/gad.403406...
    8 KB (1,015 words) - 20:57, 1 October 2022
  • the 5' UTR. A number of transcription factors such as FOXP1, SOX5, SOX6, SOX4, and MZF1 are likely to bind with the promoter, often acting to downregulate...
    18 KB (1,883 words) - 08:31, 12 December 2023
  • regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3". Proceedings of the National Academy of Sciences of the United...
    36 KB (4,682 words) - 15:54, 2 April 2024
  • Thumbnail for Syntenin-1
    EFNB1, GRIK1, GRIK2, Interleukin 5 receptor alpha subunit, Merlin, RAB5A, SOX4, TRAF6, ULK1. and ERICH2 GRCh38: Ensembl release 89: ENSG00000137575 – Ensembl...
    11 KB (1,267 words) - 07:46, 15 January 2024
  • affecting primary tumor growth. miR-335 targets multiple pathways, including SOX4, MERTK, PTPRN2 and TNC, which contribute to metastasis-suppression. miR-335...
    14 KB (1,578 words) - 21:16, 27 June 2024
  • Thumbnail for Interleukin 5 receptor alpha subunit
    which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms...
    12 KB (1,569 words) - 05:04, 1 January 2024
  • Thumbnail for FOXP1
    outflow tract separation of the pulmonary artery and aorta, and expression of Sox4 in cushions and myocardium. Foxp1 is also an important gene in muscle development...
    12 KB (1,480 words) - 05:45, 5 August 2024
  • Thumbnail for RAD21
    co-localization with CTCF-independent pluripotency factors (Oct4, Nanog, Sox4, and KLF2). RAD21 cooperates with CTCF, tissue-specific transcription factors...
    57 KB (5,500 words) - 03:35, 15 April 2024
  • Thumbnail for IRX3
    regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3". Proceedings of the National Academy of Sciences of the United...
    8 KB (937 words) - 03:11, 29 September 2024
  • Thumbnail for SAE1
    Zhao J, Li W, Liu H, Gong W, Zhou T, Zhang X (2006). "Ubc9 interacts with SOX4 and represses its transcriptional activity". Biochem. Biophys. Res. Commun...
    10 KB (1,461 words) - 22:50, 27 March 2024
  • Thumbnail for TBX3
    can interact with other transcription factors such as Nkx2-5, Msx 1/2 and Sox4 to assist it binding to its target genes to regulate heart development and...
    39 KB (4,686 words) - 17:28, 22 August 2024