Self-protein refers to all proteins endogenously produced by DNA-level transcription and translation within an organism of interest. This does not include...

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...

the body ("self-protein" or "self antigens") or from the external environment ("non-self"). The immune system identifies and attacks "non-self" external...

replication. This self-replication dramatically increases both the amount of RNA and the time of expression. Consequently, the amount of protein produced from...

the body's immune system produces antibodies against self-protein, particularly against proteins in the cell nucleus. These antibody attacks are the immediate...

cells that react with self-protein and is present in all individuals, even in normal health state. It causes autoimmune diseases if self-reactivity can lead...

In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest...

displays a small peptide (a molecular fraction of a protein) called an epitope. The presented self-antigens prevent an organism's immune system from targeting...

the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized (as in the case...

S-haplotype-specific F-box protein", as explained (parenthetically) in the abstract of], while SI in the other species with S-RNAse functions through non-self recognition...

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...

Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor...

disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. (Antibodies to thyroglobulin...

Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers – specifically polypeptides – formed...

A prion /ˈpriːɒn/ is a misfolded protein that induces misfolding in normal variants of the same protein, leading to cellular death. Prions are responsible...

disorder Autoimmune disease, immune response to self-proteins Allergy, immune response to harmless non-self proteins Histamine Immunosenescence, age-associated...

The green fluorescent protein (GFP) is a protein that exhibits green fluorescence when exposed to light in the blue to ultraviolet range. The label GFP...

as plain outside North America), self-rising flour, and cake flour (including bleached flour). The higher the protein content the harder and stronger the...

with a high affinity for self peptides or MHC. This eliminates cells which would direct immune responses towards self-proteins in the periphery. Negative...

attack self proteins are not allowed to live. In essence, every individual's immune system is tuned to the specific set of HLA and self proteins produced...

Polypeptides that have a molecular mass of 10,000 Da or more are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and...

Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure...

The MIT Press, Cambridge, MA. Alex Kentsis (2004), Self-organization of biological systems: Protein folding and supramolecular assembly, Ph.D. Thesis,...

The tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from the...

distinct pathways for processing of antigens from an organism's own (self) proteins or intracellular pathogens (e.g. viruses), or from phagocytosed pathogens...

G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors...

g., myelin basic protein) Myelin destruction, inflammation Rheumatoid arthritis Possibly collagen and/or citrullinated self proteins Chronic arthritis...

covalent process of changing proteins following protein biosynthesis. PTMs may involve enzymes or occur spontaneously. Proteins are created by ribosomes,...

which indicates that they have been exposed to "foreign" (or "non-self") proteins in the past and have developed antibodies to them. These antibodies...

against them. The result is the sensitization of immune cells against a self-protein, causing an autoimmune attack on both the damaged eye and the non-damaged...