Signaling lymphocytic activation molecule (SLAM) is a family of genes. Homophilic binding between SLAMs is involved in cell-to-cell adhesion during antigen...

Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. Recently SLAMF1 has also been designated CD150...

differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans...

an enzyme used in research SLAM-associated protein, a signaling lymphocytic activation molecule Select Agent Program of the CDC to regulate select agents...

Elotuzumab is an immunostimulatory antibody that targets the Signaling Lymphocytic Activation Molecule Family member 7 (SLAMF7) through two mechanisms. In May...

CD244 is a type-I transmembrane protein belonging to the signaling lymphocytic activation molecule family of receptors (SLAMF) which are expressed in different...

The following is a list of human clusters of differentiation (or CD) molecules. * = group; ** = not listed on hcdm Bennett JS. Structure and function...

Elotuzumab is an immunostimulatory antibody that targets the Signaling Lymphocytic Activation Molecule Family member 7 (SLAMF7) through two mechanisms. In May...

date: complement regulatory molecule CD46, the signaling lymphocyte activation molecule (SLAMF1) and the cell adhesion molecule Nectin-4. For wild type and...

missile project of the 1950, nicknamed the flying crowbar Signaling lymphocytic activation molecule (or SLAM), a family of genes Body slam, any move in which...

signaling pathway is initiated by ligand binding to the extracellular domains of the receptor. Upon binding, the tyrosine residues in the signaling motifs...

"SLAM" refers to signaling lymphocytic activation molecules. It is a SH2 domain–containing molecule (part of a family of such molecules) that plays a role...

recognizing changes of a surface molecule called major histocompatibility complex (MHC) class I. NK cells are activated in response to a family of cytokines...

G protein signaling. PIP3 binds and inhibits the RGS4 GAP. Such inhibition of GAP may perhaps "prime" the signaling pathway for activation. This creates...

cells. Through biochemical signaling and by physically acquiring antigens from the immune synapses, the BCR controls the activation of the B cell. B cells...

from T cell-dependent activation. As with TD antigens, B cells activated by TI antigens need additional signals to complete activation, but instead of receiving...

follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)". J. Immunol. 185 (1): 190–202. doi:10...

(Oct 1998). "CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling". Journal of Immunology. 161 (8): 4058–65. doi:10...

doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282. "Acute Lymphocytic Leukemia – Cancer Stat Facts". SEER. Retrieved 20 December 2017. Tubergen...

Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, Hashimoto's disease, and autoimmune thyroiditis is an autoimmune disease in which...

cell ready to respond to antigen. B cell activation follows engagement of the cell-bound antibody molecule with an antigen, causing the cell to divide...

of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and...

without signals from outside the cell. Ras is a small GTPase that hydrolyses GTP into GDP and phosphate. Ras is activated by growth factor signaling (i.e...

re-activation of these NK cells appears to be one mechanism of action induced by checkpoint-blockade. Signaling through TLR can effectively activate NK...

recruits Src homology 2 (SH2) domain–containing signaling proteins. These proteins can then initiate signaling pathways. Of all these proteins, the protein...

cytokines and the activation of monocytes. It is used to slow down the progression of multiple sclerosis. IFN-γ is able to trigger lymphocytic apoptosis. Prolonged...

component of T cell activation and development. ZAP-70 expression in B cells is correlated with the development of chronic lymphocytic leukemia (CLL). The...

"Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229". J. Immunol...

PI3K activation phosphorylates and activates AKT, localizing it in the plasma membrane. AKT can have a number of downstream effects such as activating CREB...

antigen-presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety...