Succinyl-coenzyme A, abbreviated as succinyl-CoA (/ˌsʌksɪnəlˌkoʊˈeɪ/) or SucCoA, is a thioester of succinic acid and coenzyme A. It is an important intermediate...

Succinyl coenzyme A synthetase (SCS, also known as succinyl-CoA synthetase or succinate thiokinase or succinate-CoA ligase) is an enzyme that catalyzes...

characterization of Helicobacter pylori succinyl CoA:acetoacetate CoA-transferase, a novel prokaryotic member of the CoA-transferase family". The Journal of...

methylmalonyl-CoA mutase (requiring B12 as a coenzyme) to form succinyl-CoA. The succinyl-CoA formed then enters the citric acid cycle. However, whereas acetyl-CoA...

Methylmalonyl-CoA is the thioester consisting of coenzyme A linked to methylmalonic acid. It is an important intermediate in the biosynthesis of succinyl-CoA, which...

B12-dependent enzyme catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA in humans. Mutations in MUT gene may lead to various types of methylmalonic...

yield both propionyl-CoA as well as acetyl-CoA. Propionyl-CoA is later converted into succinyl-CoA through biotin-dependant propionyl-CoA carboxylase (PCC)...

generated from succinyl-CoA by the enzyme succinyl-CoA synthetase in a GTP/ATP-producing step:: Section 17.1  Succinyl-CoA + NDP + Pi → Succinate + CoA + NTP Catalyzed...

In enzymology, a 3-oxoacid CoA-transferase (EC 2.8.3.5) is an enzyme that catalyzes the chemical reaction succinyl-CoA + a 3-oxo acid ⇌ {\displaystyle...

to succinyl-CoA, an ATP-dependent step Succinate + ATP + CoA ⟶ Succinyl − CoA + ADP + Pi {\displaystyle {\ce {Succinate + ATP + CoA -> Succinyl-CoA + ADP...

this enzyme in the citric acid cycle is: α-ketoglutarate + NAD+ + CoA → Succinyl CoA + CO2 + NADH This reaction proceeds in three steps: decarboxylation...

chlorophylls. The reaction is as follows: succinyl-CoA + glycine ⇌ {\displaystyle \rightleftharpoons } δ-aminolevulinic acid + CoA + CO2 This enzyme is expressed...

Succinyl-CoA:3-oxoacid CoA transferase deficiency is an inborn error of ketone body utilization. Succinyl-CoA:3-oxoacid CoA transferase catalyzes the...

to reaching succinyl-CoA. Finally, methylmalonyl-CoA mutase, a vitamin B12-dependent enzyme, converts L-methylmalonyl-CoA into succinyl-CoA using a free...

by a racemase, yielding (R)-methylmalonyl-CoA, which is then converted into succinyl-CoA by methylmalonyl-CoA mutase (one of the few metabolic enzymes...

Vitamin B 12 (as adenosylcobalamin) to make succinyl-CoA. When the conversion of propionyl-CoA to succinyl-CoA in the mitochondria fails due to Vitamin B...

the liver to other cells. The liver does not have the critical enzyme, succinyl CoA transferase, to process ketone bodies, and therefore cannot undergo ketolysis...

3-oxoacid CoA-transferase 1 (OXCT1) is an enzyme that in humans is encoded by the OXCT1 gene. It is also known as succinyl-CoA-3-oxaloacid CoA transferase...

mitochondrial methylmalonyl-CoA epimerase. Finally, mitochondrial methylmalonyl-CoA mutase with cofactor adenosylcobalamin produces succinyl-CoA which enters the...

cycle (Krebs cycle) to be oxidized for energy production. Coenzyme A (CoASH or CoA) consists of a β-mercaptoethylamine group linked to pantothenic acid...

propionyl-CoA is formed. In order to convert this to the metabolically useful succinyl-CoA, three reactions are needed. The propionyl-CoA is first carboxylated...

The enzyme succinyl-CoA hydrolase (EC 3.1.2.3) catalyzes the reaction succinyl-CoA + H2O ⇌ {\displaystyle \rightleftharpoons } CoA + succinate This enzyme...

Methylmalonyl-CoA requires vitamin B12 to form succinyl-CoA. When the amount of B12 is insufficient for the conversion of cofactor methylmalonyl-CoA into succinyl-CoA...

3-oxoadipyl-CoA Thus, the two substrates of this enzyme are succinyl-CoA and acetyl-CoA, whereas its two products are CoA and 3-oxoadipyl-CoA. This enzyme...

Methylmalonyl-CoA mutase is a mitochondrial homodimer apoenzyme (EC. 5. 4.99.2) that focuses on the catalysis of methylmalonyl CoA to succinyl CoA. The enzyme...

In enzymology, a 3-oxoadipate CoA-transferase (EC 2.8.3.6) is an enzyme that catalyzes the chemical reaction succinyl-CoA + 3-oxoadipate ⇌ {\displaystyle...

convert L-methylmalonyl-CoA to succinyl-CoA, an important step in the catabolic breakdown of some amino acids into succinyl-CoA, which then enters energy...

for acetyl-CoA and succinyl-CoA is dictated by a single residue. The physiological basis for the preference of acetyl-CoA or succinyl-CoA is unknown,...

citramalyl-CoA Thus, the two substrates of this enzyme are succinyl-CoA and citramalate, whereas its two products are succinate and citramalyl-CoA. This enzyme...

enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction succinyl-CoA + (R)-2-benzylsuccinate...