In retrosynthetic analysis, a synthon is a hypothetical unit within a target molecule that represents a potential starting reagent in the retroactive...

Synthon is a Dutch multinational that produces generic human drugs. The company was founded in 1991 by Jacques Lemmens and Marijn Oosterbaan, two organic...

single target. Synthon A fragment of a compound that assists in the formation of a synthesis, derived from that target molecule. A synthon and the corresponding...

reagent. It is often used as a synthetic equivalent for the phenyl "Ph−" synthon. Phenylmagnesium bromide is commercially available as solutions of diethyl...

C1 chemistry is the chemistry of one-carbon molecules. Although many compounds and ions contain only one carbon, stable and abundant C-1 feedstocks are...

7-ACA (7-aminocephalosporanic acid) is the core chemical structure (a synthon) for the synthesis of cephalosporin antibiotics and intermediates. It can...

distillation. Overall, decarboxylation depends upon stability of the carbanion synthon R− , although the anion may not be a true chemical intermediate. Typically...

organic cyanides are called nitriles. In organic synthesis, cyanide is a C-1 synthon; i.e., it can be used to lengthen a carbon chain by one, while retaining...

IV, Pivina TS (1999). 4-Amino-3-azidocarbonyl Furoxan as an Universal Synthon for the Synthesis of Energetic Compounds of the Furoxan Series. 30th International...

hydrocarbons, as well as the halogenated product. Haloalkanes behave as the R+ synthon, and readily react with nucleophiles. Hydrolysis, a reaction in which water...

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functional groups. Identifying supramolecular synthons simplifies this complex problem. The supramolecular synthon concept is now widely used by crystal engineers...

derivatives. With carbanions, it serves again as a source of the benzoyl cation synthon, C6H5CO+. Benzoyl peroxide, a common reagent in polymer chemistry, is produced...

SGCOxCompounds, SGCStoCompounds SMID Specs Structural Genomics Consortium SureChem Synthon-Lab Thomson Pharma Total TOSLab Building-Blocks UM-BBD UPCMLD UsefulChem...

Omnic by Astellas Pharma Europe. The largest manufacturer of tamsulosin is Synthon BV (the Netherlands).[citation needed] Tamsulosin hydrochloride is marketed...

by Biolex. In May 2012 Biolex announced that it sold the LEX System to Synthon, a Netherlands-based specialty pharmaceutical company. The sale included...

functional groups have been synthesized, serving as CO2 and α-diketone synthons. Finally, Stephen G. Davies of Oxford has designed a chiral auxiliary that...

These may be understood with key concepts such as the supramolecular synthon and the secondary building unit. The term 'crystal engineering' was first...

Dictyopterene A: Optically Active Tributylstannylcyclopropane as a Chiral Synthon". Bulletin of the Chemical Society of Japan. 73 (2): 409–416. doi:10.1246/bcsj...

(September 2001). "The Use of Carbon Monoxide and Imines as Peptide Derivative Synthons: A Facile Palladium-Catalyzed Synthesis of α-Amino Acid Derived Imidazolines"...

like the bromide analog, is a synthetic equivalent for the phenyl anion synthon. Iodobenzene reacts with chlorine to give the complex, iodobenzene dichloride...

the malonic ester can be thought of being equivalent to the −CH2COOH synthon. The esters chosen are usually the same as the base used, i.e. ethyl esters...

electrophilic character of this reagent and its use in introducing the equivalent synthon "CO2+": R−NH2 + COCl2 → R−N=C=O + 2 HCl, where R = alkyl, aryl Such reactions...

synthesis, EtBr is the synthetic equivalent of the ethyl carbocation (Et+) synthon. In reality, such a cation is not actually formed. For example, carboxylates...

Massachusetts Institute of Technology Known for Retrosynthetic analysis Synthon Corey–Bakshi–Shibata catalyst Corey–Chaykovsky reaction Corey–Fuchs reaction...

GSK) and Synthon independently developed paroxetine mesylate. They obtained two separate patents. Subsequently, all attempts to produce Synthon's version...

compounds. Apart from acting as the synthetic equivalent of an ethyl anion synthon for nucleophilic addition, ethylmagnesium bromide may be used as a strong...

4-dihydroxybutanoic acid, by using 3-hydroxy-gamma-butyrolactone as a chiral synthon It is used as one of the monomers for manufacture of some polyesters and...

in Nijmegen. Other notable companies headquartered in Nijmegen include Synthon, a Dutch multinational pharmaceutical company and Vaxxinova, an EW group...

transformations. The esters of malonic acid are also used as a −CH2COOH synthon in the malonic ester synthesis. Malonic acid is the starting substrate...