Transcription factor II H (TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision...

CDK-activating kinase (CAK) and a component of the general transcription factor TFIIH. An intricate network of cyclin-dependent kinases (CDKs) is organized in...

attracts and regulates TFIIH TFIIF – stabilizes RNA polymerase interaction with TBP and TFIIB; helps attract TFIIE and TFIIH TFIIH – unwinds DNA at the...

(TFIIH) is the key enzyme involved in dual excision. TFIIH and XPG are first recruited to the site of DNA damage (XPG stabilizes TFIIH). The TFIIH subunits...

six general transcription factors: TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. Additional regulatory complexes (such as the mediator coactivator and chromatin...

type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. The 3D-structure of the archaeal homolog of...

recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both...

bubble. TFIIH enters the complex. TFIIH is a large protein complex that contains among others the CDK7/cyclin H kinase complex and a DNA helicase. TFIIH has...

forms of CAK have been identified: free CAK and TFIIH-associated CAK. Free CAK is more abundant than TFIIH-associated CAK. Free CAK phosphorylates Cdks and...

specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH". EMBO J. 16 (7): 1628–37. doi:10.1093/emboj/16.7.1628. PMC 1169767. PMID 9130708...

characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH". Proc. Natl. Acad. Sci. U.S.A. 93 (13): 6482–7. Bibcode:1996PNAS...

factors for RNA polymerase II include TFIID, TFIIA, TFIIB, TFIIF, TFIIE, and TFIIH. The transcription, a complete set of general transcription factors and...

TFIIH subunit XPD is a protein that in humans is encoded by the ERCC2 (ERCC excision repair 2) gene. It is a component of the general transcription and...

biology, this protein domain represents Tbf5 which stands for TTDA subunit of TFIIH basal transcription factor complex (also known as subunit 5 of RNA polymerase...

of CTD is catalyzed by one of the six general transcription factors, TFIIH. TFIIH serves two purposes: one is to unwind the DNA at the transcription start...

protein that stabilizes the multi-subunit transcription repair factor IIH(TFIIH). TFIIH plays a key role in a major DNA repair process, nucleotide excision...

in the development of skin cancer. XPD is an essential component of the TFIIH complex, a transcription and repair factor in the cell. As part of this...

CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two...

of archaeal TFE), TFIIF, and TFIIH. The TFIID is the first component to bind to DNA due to binding of TBP, while TFIIH is the last component to be recruited...

kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein...

biological target of triptolide is believed to be the XPB subunit of the TFIIH protein complex (involved in DNA repair and transcription initiation). Tripfordines...

TBP-associated factors (TAFs), as well as the factors TFIIB, TFIIE, TFIIF, and TFIIH. Together, these factors are responsible for promoter recognition and the...

molecules Receptors Cell surface Intracellular Co-receptor Second messenger Transcription factors General Transcription preinitiation complex TFIID TFIIH...

combination with the XPB helicase-containing transcription/repair complex TFIIH, is employed in unwinding the DNA duplex after damage is initially recognized...

molecules Receptors Cell surface Intracellular Co-receptor Second messenger Transcription factors General Transcription preinitiation complex TFIID TFIIH...

molecules Receptors Cell surface Intracellular Co-receptor Second messenger Transcription factors General Transcription preinitiation complex TFIID TFIIH...

Cys2His2 General transcription factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1...

molecules Receptors Cell surface Intracellular Co-receptor Second messenger Transcription factors General Transcription preinitiation complex TFIID TFIIH...

molecules Receptors Cell surface Intracellular Co-receptor Second messenger Transcription factors General Transcription preinitiation complex TFIID TFIIH...

transcription via inhibition of the XPB subunit of the general transcription factor TFIIH has been recently reported as a glucose conjugate for targeting hypoxic...