• Thumbnail for Tert-Butyloxycarbonyl protecting group
    The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group (BOC group) is an acid-labile protecting group used in organic synthesis...
    10 KB (1,045 words) - 17:06, 19 July 2024
  • Thumbnail for Di-tert-butyl dicarbonate
    a tert-butoxycarbonyl (Boc) group, it is commonly referred to as Boc anhydride. This pyrocarbonate reacts with amines to give N-tert-butoxycarbonyl or...
    13 KB (1,222 words) - 20:59, 16 December 2023
  • Thumbnail for Tert-Butyldimethylsilyl chloride
    Protected Vicinal Amino Alcohols: (S)-2-[(4s)-n-tert-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidinyl]-2-tert-butyldimethylsiloxyethanal from a Serine-Derived...
    4 KB (276 words) - 03:16, 11 February 2024
  • group) Alkynyl group (propargyl group) Benzyloxycarbonyl group (Cbz) tert-butoxycarbonyl group (Boc) Carboxyl group IUPAC, Compendium of Chemical Terminology...
    1,022 bytes (105 words) - 01:37, 24 November 2023
  • Thumbnail for Sacubitril
    chloride using sodium hydroxide and protection of the free amine with a tert-butoxycarbonyl (Boc) group. The primary alcohol is oxidized using bleach with TEMPO...
    7 KB (526 words) - 15:48, 25 March 2024
  • Thumbnail for Photoresist
    would change by the photogenerated acid. The acid deprotects the tert-butoxycarbonyl (t-BOC), inducing the resist from alkali-insoluble to alkali-soluble...
    29 KB (3,241 words) - 09:30, 11 August 2024
  • fashion, the intermediate isocyanate can be trapped by tert-butyl alcohol, yielding the tert-butoxycarbonyl (Boc)-protected amine. The Hofmann Rearrangement...
    8 KB (770 words) - 23:55, 31 August 2024
  • Thumbnail for Protecting group
    it evolves carbon dioxide. The commonest-used carbamates are the tert-butoxycarbonyl, benzoxycarbonyl, fluorenylmethylenoxycarbonyl, and allyloxycarbonyl...
    57 KB (6,755 words) - 23:19, 9 April 2024
  • Thumbnail for Pinacolborane
    C7 Functionalization of Tryptophan. Synthesis of Methyl (S)-2-((tert-Butoxycarbonyl)amino)-3-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-3-yl)propanoate"...
    5 KB (446 words) - 11:30, 5 January 2024
  • Thumbnail for Triethylsilane
    Protected Vicinal Amino Alcohols: (S)-2-[(4S)-N-tert-Butoxycarbonyl-2,2-Dimethyl-1,3,-oxazolidinyl]-2-tert-butyldimethylsiloxyethanal from a Serine-Derived...
    3 KB (244 words) - 10:10, 6 July 2022
  • system. British Overseas citizen, one kind of British nationality tert-Butoxycarbonyl, abbreviated as "Boc", "BOC" or "t-Boc", a protecting group used...
    3 KB (485 words) - 19:31, 5 January 2023
  • Thumbnail for Pyrrolizidine alkaloid
    their derivatives. A flexible strategy would be to start with a Boc (tert-Butoxycarbonyl) protected pyrrole molecule and use specific reaction for synthesis...
    37 KB (3,571 words) - 22:15, 15 September 2024
  • Thumbnail for Hydroxyethyl acrylate
    Pressure-Sensitive Adhesive Copolymers of 2-Hydroxyethyl Acrylate Protected with tert -Butoxycarbonyl Group in the Presence of Cross-Linker and Lewis Acid". ACS Omega...
    9 KB (773 words) - 01:41, 21 March 2024
  • Thumbnail for N-t-BOC-MDMA
    Salouros H (March 2017). "Identification and characterization of N-tert-butoxycarbonyl-MDMA: a new MDMA precursor". Drug Testing and Analysis. 9 (3): 399–404...
    5 KB (427 words) - 09:25, 4 October 2024
  • Thumbnail for Tris(o-tolyl)phosphine
    Richard F. W. Jackson; Manuel Perez-Gonzalez (2005). "Synthesis of N-(Tert-butoxycarbonyl)-β-iodoalanine Methyl Ester: A Useful Building Block in the Synthesis...
    2 KB (156 words) - 17:22, 30 September 2023
  • Thumbnail for Docetaxel
    Docetaxel (category Tert-Butyl esters)
    functional group on carbon 10, whereas paclitaxel has an acetate ester, and a tert-butyl carbamate ester exists on the phenylpropionate side chain instead of...
    45 KB (4,765 words) - 15:32, 26 September 2024
  • Thumbnail for Pentagastrin
    Pentagastrin (category Tert-Butyl esters)
    Elimination half-life 10 minutes or less Identifiers IUPAC name N-(tert-butoxycarbonyl)-β-alanyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide...
    5 KB (419 words) - 11:36, 19 December 2023
  • Thumbnail for Tellurocysteine
    yield from a protected form of 3-iodoalanine. Thus, methyl (2R)-2-[(tert-butoxycarbonyl)amino]-3-iodopropionate reacts with lithium telluride to produce...
    4 KB (345 words) - 00:05, 21 August 2024
  • activation of 5 involving simultaneous indolamide formation and tert-butoxycarbonyl (Boc) removal gives the active amide 6 which allows cyclization to...
    22 KB (2,289 words) - 13:18, 29 June 2024
  • Thumbnail for Chloroalanine
    Richard F. W. Jackson; Manuel Perez-Gonzalez (2005). "Synthesis of N-(Tert-butoxycarbonyl)-β-iodoalanine Methyl Ester: A Useful Building Block in the Synthesis...
    3 KB (249 words) - 13:41, 5 September 2024
  • Thumbnail for Tesetaxel
    Tesetaxel (category Tert-butyl compounds)
    3S,4S,6S,8aR,10S,11aS,11bR,13aR)-2a-(acetyloxy)-6-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-3-(3-fluoropyridin-2-yl)-2-hydroxypropanoyl]oxy}-10-[(dim...
    4 KB (221 words) - 08:54, 10 June 2024
  • Thumbnail for Ortataxel
    7R,8aS,9S,10aR,12aS,13S,13aS)-7,12a-bis(acetyloxy)-4-({(2R,3S)-3-[tert-butoxycarbonyl)amino]-2-hydroxy-5-methylhexanoyl}oxy)-9-hydroxy-5,8a,14,14-tetramethyl-2...
    3 KB (90 words) - 23:59, 28 January 2023
  • Thumbnail for SYM-2081
    SYM-2081 can be produced at a multi-gram scale by starting with (S)-1-t-butoxycarbonyl-5-t-butyldiphenylsilyoxymethylpyrrolidine-2-one and treating it with...
    4 KB (338 words) - 16:03, 3 November 2023
  • Thumbnail for Danoprevir
    of NS3/4A HCV protease. It contains acylsulfonamide, fluoroisoindole and tert-butyl carbamate moieties. Danoprevir is a clinical candidate based on its...
    7 KB (487 words) - 04:54, 20 October 2023
  • Thumbnail for Substituted tryptamine
    Zgombick JM, Liang SX, Kohlman DT, Audia JE (February 1999). "N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonist". Journal...
    72 KB (1,779 words) - 22:06, 10 October 2024
  • Thumbnail for Quisqualic acid
    conversion of L-serine to its N-t-butoxycarbonyl derivative. Amine group of serine has to be protected, so di-tert-butyldicarbonate in isopropanol and...
    31 KB (3,541 words) - 16:24, 7 October 2024