• Thumbnail for Tight junction
    Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are multiprotein junctional complexes whose canonical...
    14 KB (1,531 words) - 06:39, 10 August 2024
  • Tight junction proteins (TJ proteins) are molecules situated at the tight junctions of epithelial, endothelial and myelinated cells. This multiprotein...
    14 KB (1,909 words) - 14:43, 15 May 2024
  • Thumbnail for Cell junction
    of cell junction: Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions) Gap junctions (communicating junction) Tight junctions (occluding...
    20 KB (2,248 words) - 10:19, 16 July 2024
  • Tight junction protein are proteins that are involved in the formation and functioning of tight junctions; "Tight junction protein" may refer to: TJP1...
    551 bytes (86 words) - 17:14, 2 November 2017
  • Thumbnail for Tight junction protein ZO-1
    Tight junction protein ZO-1 also known as Zonula Occludens-1 (ZO-1), is a 220-kD peripheral membrane protein that is encoded by the TJP1 gene in humans...
    16 KB (2,034 words) - 12:25, 6 September 2024
  • Thumbnail for Gap junction
    molecules, substrates, and metabolites. Gap junctions were first described as close appositions as other tight junctions, but following electron microscopy studies...
    90 KB (10,627 words) - 05:06, 28 September 2024
  • Thumbnail for Intestinal epithelium
    of cell junction which can be identified at the ultrastructural level: Gap junctions Desmosomes Adherens junctions Tight junctions Gap junctions bring the...
    26 KB (2,933 words) - 06:35, 22 June 2024
  • Thumbnail for Adherens junction
    cell–matrix junctions in epithelial and endothelial tissues, usually more basal than tight junctions. An adherens junction is defined as a cell junction whose...
    5 KB (505 words) - 05:55, 18 April 2024
  • junctions is dependent on a variety of factors including protein makeup of that junction, tissue type and signaling from the cells. Tight junctions are...
    17 KB (2,221 words) - 04:19, 27 May 2024
  • Thumbnail for Cell adhesion
    filaments in order to maintain structure of the tight junction. Claudins, essential for formation of tight junctions, form paracellular pores which allow selective...
    32 KB (3,663 words) - 00:22, 23 August 2024
  • Thumbnail for Junctional adhesion molecule
    short amino acid sequences at the C-terminus of proteins, to form tight junctions in both epithelial and endothelial cells as polarity is gained in the...
    15 KB (1,824 words) - 07:31, 26 August 2023
  • Thumbnail for Occludin
    localized at the tight junctions. Together with Claudins, and zonula occludens-1 (ZO-1), occludin has been considered a staple of tight junctions, and although...
    24 KB (2,898 words) - 06:03, 10 June 2024
  • synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It has been studied...
    8 KB (640 words) - 22:48, 10 August 2024
  • Thumbnail for Lactiferous duct
    casein content. Prolactin and/or placental lactogen are required for tight junction closure while progesterone is the main hormone preventing closure before...
    5 KB (469 words) - 14:31, 27 February 2024
  • human intestine, small particles (< 4 Å in radius) can migrate through tight junction claudin pore pathways, and particles up to 10–15 Å (3.5 kDa) can transit...
    26 KB (2,845 words) - 13:37, 28 September 2024
  • Thumbnail for Tight junction protein ZO-2
    Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins (TJPs) belong to a family of membrane-associated...
    10 KB (1,201 words) - 07:37, 16 July 2024
  • Thumbnail for Claudin
    occludin, are the most important components of the tight junctions (zonulae occludentes). Tight junctions establish the paracellular barrier that controls...
    11 KB (1,301 words) - 05:45, 16 July 2024
  • Thumbnail for Blood–brain barrier
    these tight junction proteins is stabilized to the endothelial cell membrane by another protein complex that includes scaffolding proteins such as tight junction...
    39 KB (4,361 words) - 04:15, 30 September 2024
  • plasma membrane with little cross-linking of the tight junctional strands. At this time, the tight junctions are quite 'leaky' allowing movement of fluid...
    12 KB (1,667 words) - 08:57, 18 May 2024
  • Thumbnail for Septate junction
    (vertebrate) tight junctions; however, tight and septate junctions are different in many ways. Known insect homologues of tight junction components are...
    10 KB (1,197 words) - 19:42, 16 September 2024
  • Thumbnail for Stress fiber
    well as ZO-1, ZO-2 and ZO-3, which link tight junctions to the actin cytoskeleton. However, tight junctions have not been found to be directly linked...
    24 KB (3,025 words) - 13:01, 3 October 2024
  • Thumbnail for CLDN1
    is encoded by the CLDN1 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial...
    8 KB (946 words) - 13:11, 5 March 2024
  • Thumbnail for Actinidain
    kiwifruit, the enzyme is under preliminary research for its effect on tight junction proteins of intestinal epithelial cells. Actinidain is commercially...
    16 KB (1,922 words) - 08:00, 1 September 2024
  • Thumbnail for Cerebral edema
    of astrocytes and pericytes joined with adhesion proteins producing tight junctions. Return of blood flow to these cells after an ischemic stroke can cause...
    70 KB (7,820 words) - 06:59, 12 July 2024
  • Thumbnail for Edema
    processes are, among others, the transmembrane proteins occludin, claudins, tight junction protein ZO-1, cadherins, catenins and actinin, which are directed by...
    30 KB (3,283 words) - 16:40, 26 August 2024
  • Thumbnail for Neuroeffector junction
    transmission. These are tight junctions, but in the autonomic nervous system and enteric nervous system the connecting junctions become much "looser", allowing...
    24 KB (3,241 words) - 10:35, 16 July 2024
  • of 0.16%. Some claudins form tight junction-associated pores that allow paracellular ion transport. The tight junctions have a net negative charge, and...
    9 KB (1,021 words) - 00:20, 4 January 2024
  • (haptoglobin 2 precursor) is a protein that increases the permeability of tight junctions between cells of the wall of the digestive tract. It was discovered...
    4 KB (418 words) - 13:25, 11 April 2024
  • Thumbnail for CLDN5
    Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and...
    7 KB (840 words) - 03:09, 22 January 2024
  • Thumbnail for Blood–testis barrier
    and by Sertoli cells. The barrier is formed by tight junctions, adherens junctions and gap junctions between the Sertoli cells, which are sustentacular...
    5 KB (643 words) - 19:41, 9 June 2024