• Thumbnail for Persistent carbene
    nitrogen atoms in triazol-5-ylidene, there are two possible isomers, namely 1,2,3-triazol-5-ylidenes and 1,2,4-triazol-5-ylidenes. The triazol-5-ylidenes based...
    62 KB (6,933 words) - 11:59, 13 August 2024
  • The triazol-5-ylidenes are a group of persistent carbenes which includes the 1,2,4-triazol-5-ylidene system and the 1,2,3-triazol-5-ylidene system. As...
    22 KB (2,758 words) - 23:40, 9 December 2023
  • Thumbnail for 3-Amino-1,2,4-triazole
    3-Amino-1,2,4-triazole Names IUPAC name 1H-1,2,4-Triazol-3-amine Other names 1,2,4-Triazol-3-amine aminotriazole Amitrol Amitrole 3-Aminotriazole 2-Amino-1...
    7 KB (522 words) - 12:31, 20 September 2024
  • Thumbnail for Nitrotriazolone
    Semicarbazide hydrochloride is condensed with formic acid to produce 1,2,4-triazol-3-one, which is nitrated with nitric acid to form nitrotriazolone. In vivo...
    7 KB (445 words) - 11:35, 6 September 2023
  • Thumbnail for Anastrozole
    benzyl triazole. It is also known as α,α,α',α'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile. Anastrozole is structurally related...
    27 KB (2,332 words) - 04:27, 27 February 2024
  • Thumbnail for Efinaconazole
    (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol CAS Number 164650-44-6 PubChem CID 489181 DrugBank DB09040...
    10 KB (715 words) - 01:12, 2 September 2024
  • Thumbnail for Bomedemstat
    2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-(4-methylpiperazin-1-yl)-1-oxopentan-2-yl]-4-(triazol-1-yl)benzamide) is an investigational drug under development by Imago BioSciences...
    11 KB (1,085 words) - 10:41, 5 September 2024
  • Thumbnail for Fluconazole
    61–88% Identifiers IUPAC name 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol CAS Number 86386-73-4 Y PubChem CID 3365 DrugBank DB00196 Y...
    31 KB (2,821 words) - 10:58, 27 May 2024
  • Thumbnail for Trazodone
    Trazodone (category 1,2,4-Triazol-3-ones)
    Trazodone, sold under many brand names, is an antidepressant medication, used to treat major depressive disorder, anxiety disorders, and insomnia. It is...
    115 KB (10,953 words) - 21:57, 10 October 2024
  • Thumbnail for Suvorexant
    oxazolyl)hexahydro-7-methyl-1H-1,4-diazepin-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone. Its molecular formula is C23H23N6O2Cl and its molecular...
    94 KB (8,941 words) - 16:56, 16 September 2024
  • Thumbnail for Aprepitant
    5-bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a potent, orally active, long-acting morpholine...
    23 KB (2,208 words) - 05:59, 6 October 2024
  • Thumbnail for 2,4-Dinitrophenol
    explosive formulation constituents: 2,4-Dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine". Journal of Hazardous Materials. 280:...
    35 KB (3,728 words) - 17:44, 30 September 2024
  • Thumbnail for Deferasirox
    acid in the presence of base to give 4-(3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl)benzoic acid (deferasirox). Deferasirox ranked second on the list...
    11 KB (783 words) - 04:50, 7 September 2024
  • Thumbnail for Tebuconazole
    4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan- 3-ol Other names (±)-1-(4-Chlorophenyl)-4,4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan-3-ol Identifiers...
    4 KB (198 words) - 17:45, 7 September 2024
  • Thumbnail for Daridorexant
    -benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone. Its molecular formula is C23H23N6O2Cl and its molecular...
    48 KB (4,078 words) - 11:27, 24 July 2024
  • Thumbnail for Letrozole
    half-life 2 days Excretion Kidney Identifiers IUPAC name 4,4'-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile CAS Number 112809-51-5 Y PubChem CID 3902...
    20 KB (1,820 words) - 06:05, 2 June 2024
  • Thumbnail for ASP2535
    (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive...
    2 KB (141 words) - 19:45, 20 September 2024
  • Thumbnail for TPA-023
    A, et al. (November 2005). "7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally...
    7 KB (638 words) - 14:12, 5 September 2024
  • Thumbnail for MRK-409
    3-b)pyridazine, 7-cyclobutyl-3-(2,6-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-". "MRK-409". go.drugbank.com. Retrieved 2024-02-09. Atack...
    4 KB (319 words) - 15:54, 30 March 2024
  • "3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile". pubchem.ncbi.nlm.nih.gov. Retrieved...
    5 KB (492 words) - 03:33, 27 August 2024
  • Thumbnail for Tris(benzyltriazolylmethyl)amine
    Names Preferred IUPAC name 1-(1-Benzyl-1H-1,2,3-triazol-4-yl)-N,N-bis[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]methanamine Identifiers CAS Number 510758-28-8 Y...
    4 KB (279 words) - 02:00, 22 August 2022
  • Thumbnail for Asundexian
    Investigational Identifiers IUPAC name 4-[[(2S)-2-[4-[5-Chloro-2-[4-(trifluoromethyl)triazol-1-yl]phenyl]-5-methoxy-2-oxopyridin-1-yl]butanoyl]amino]-2-fluorobenzamide...
    6 KB (351 words) - 06:02, 5 April 2024
  • Thumbnail for Seltorexant
    6-Dimethylpyrimidin-2-yl)-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-(2-fluoro-6-[1,2,3]triazol-2-ylphenyl)methanone CAS Number 1293281-49-8 Y PubChem CID 67116280 ChemSpider...
    7 KB (498 words) - 08:59, 15 September 2024
  • Interesting examples of abnormal NHCs are based on the mesoionic 1,2,3-triazol-5-ylidene structure. An efficient, cationic palladium catalyst of PEPPSI...
    48 KB (5,450 words) - 14:18, 26 September 2024
  • Thumbnail for Cyproconazole
    Cyproconazole Names IUPAC name 2-(4-Chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol Identifiers CAS Number 94361-06-5 Y 3D model (JSmol) Interactive...
    15 KB (1,546 words) - 12:34, 13 September 2024
  • Thumbnail for Deucravacitinib
    IUPAC name 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)phenyl)amino)-N-(trideuteromethyl)pyridazine-3-carboxamide CAS Number...
    12 KB (697 words) - 09:25, 1 July 2024
  • Thumbnail for Opelconazole
    Identifiers IUPAC name 4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]-3-methylphenyl]piperazin-1-yl]-N-(4-fl...
    4 KB (161 words) - 15:09, 7 September 2024
  • Thumbnail for List of benzodiazepines
    4]diazepin-2(3H)-one 21738192 Compound 6a 9.5 † 7-chloro-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one JC-184 7-bromo-5-(2-thienyl)-1H-benzo[e]...
    108 KB (3,088 words) - 21:34, 19 September 2024
  • Thumbnail for Substituted tryptamine
    Rizatriptan artificial 5-(CH2(N3(CH)2)) CH3 CH3 N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine 145202-66-0 Sumatriptan artificial...
    72 KB (1,779 words) - 22:06, 10 October 2024
  • Thumbnail for Voriconazole
    (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol CAS Number 137234-62-9 Y PubChem CID 71616 DrugBank DB00582 Y...
    15 KB (1,166 words) - 06:50, 14 August 2024