The trifluoromethyl group is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula...

organic chemistry describes any organic reaction that introduces a trifluoromethyl group in an organic compound. Trifluoromethylated compounds are of some...

formed. An electron donating group (EDG) or electron releasing group (ERG, Z in structural formulas) is an atom or functional group that donates some of its...

diazonium salts are a group of organic compounds sharing a common functional group [R−N+≡N]X− where R can be any organic group, such as an alkyl or an...

additional stabilization is achieved by the trifluoromethyl group, which acts as a strong electron-withdrawing group using the sulfur atom as a bridge. Triflates...

3 whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom;...

fluorine atoms and consequent electron-withdrawing nature of the trifluoromethyl group weakens the oxygen-hydrogen bond (allowing for greater acidity)...

principle, the trichloromethyl group generally lowers the basicity of organic compounds, e.g. trichloroethanol. Trifluoromethyl group Trichloromethoxy "Trichloromethyl...

replaces some fluorine atoms with trifluoromethyl groups, perfluoroalkoxy alkanes do the same with trifluoromethoxy groups, and Nafion contains perfluoroether...

(same structure as clenbuterol but one of the chloro groups has been changed to a trifluoromethyl group instead). Cimaterol Center for Veterinary Medicine...

drugs and agrochemicals contain only one fluorine center or one trifluoromethyl group. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...

esters are named. For example, if the R2 group is a methyl group and the R1 group is a trifluoromethyl group, the resulting compound is methyl trifluoromethanesulfonate...

drugs and agrochemicals contain only one fluorine center or one trifluoromethyl group. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...

TFNM) is a toxic organic compound consisting of a trifluoromethyl group covalently bound to a nitroso group. Its distinctive deep blue color is unusual for...

a reagent used in organic chemistry for the introduction of the trifluoromethyl group. The compound was first prepared in 1984 by Ingo Ruppert and further...

organohalides. Notably, many pharmaceuticals such as Prozac have trifluoromethyl groups. For information on inorganic halide chemistry, see halide. Halocarbons...

2C-CF3, a name derived from the Para-trifluoromethyl group it contains. 2C-TFM is a code that represents 4-trifluoromethyl-2,5-dimethoxyphenethylamine. The...

system has low steric hindrance to maximize potency, while the 3-trifluoromethyl group provides superior selectivity and potency. To explain the selectivity...

smell reminiscent of ethanol. Due to the electronegativity of the trifluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol...

collected. A presence of a strong electronegative group in the substrate such as the trifluoromethyl group is a prerequisite. The effect disappears when a...

this compound was found to be a suitable reagent for introducing trifluoromethyl groups onto electron-rich aromatic compounds by Langlois; this reagent...

an analogue of bisphenol A in which the two methyl groups are replaced with trifluoromethyl groups. It exists as a white to light-gray powder. Bisphenol...

tetrafluoride reacts with alkynes connected to trifluoromethyl groups to add difluorophosphino (-PF2) groups on each side of a double bond. Other kinds of...

interaction between the trifluoromethyl group and the hydrophobic pocket created by Ile-293, Leu-298, Leu-354, and Val-379. This group can also be linked to...

timoprazole was the benzimidazole part of its structure. Addition of a trifluoromethyl group to the benzimidazole moiety led to a series of very active compounds...

constant is about 10+6, due to the electron withdrawing effect of the trifluoromethyl groups. Similarly, the conversion of chloral (Cl 3C)HC=O to chloral hydrate...

species bis(trifluoromethyl)acetolactone ((CF 3) 2C 2O 2), which has increased electronic stabilisation due to its two trifluoromethyl groups, is known...

Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate is an anion with chemical formula [{3,5-(CF3)2C6H3}4B]−, which is commonly abbreviated as [BArF4]−, indicating...

functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo...

a sulfonium salt that serves as an electrophilic source of the trifluoromethyl group and that is precedented to react via a single-electron transfer...