A trifunctional antibody is a monoclonal antibody with binding sites for two different antigens, typically CD3 and a tumor antigen, making it a type of...
12 KB (1,444 words) - 07:52, 29 April 2024
variable fragment sdAb: single-domain antibody BsAb: bispecific monoclonal antibody: 3funct: trifunctional antibody BiTE: bi-specific T-cell engager This...
135 KB (4,013 words) - 06:50, 25 June 2024
The most common types are called trifunctional antibodies, as they have three unique binding sites on the antibody: the two Fab regions, and the Fc region...
29 KB (3,308 words) - 18:16, 18 March 2024
Catumaxomab (category Drugs that are a monoclonal antibody)
2007). "Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer". British Journal of Cancer...
8 KB (709 words) - 20:33, 1 December 2023
termed trifunctional antibodies, had the substem -axo-. Newer antibody names omit this part of the name. The substem preceding the source of the antibody refers...
34 KB (2,906 words) - 19:36, 1 November 2023
Ertumaxomab (category Drugs that are a monoclonal antibody)
is a rat-murine hybrid monoclonal antibody designed to treat some types of cancer. It is a trifunctional antibody which works by linking T-lymphocytes...
2 KB (118 words) - 04:19, 3 April 2023
ZMapp (category Monoclonal antibodies)
experimental biopharmaceutical drug comprising three chimeric monoclonal antibodies under development as a treatment for Ebola virus disease. Two of the three...
24 KB (2,654 words) - 05:16, 24 November 2023
concomitant cell therapy with allogeneic lymphocytes and trifunctional bispecific antibody". Experimental Hematology. 36 (8): 997–1003. doi:10.1016/j...
34 KB (3,917 words) - 20:36, 19 June 2024
Toxic myopathies Unwanted breast growth Oligospermia Penicillamine is a trifunctional organic compound, consisting of a thiol, an amine, and a carboxylic...
16 KB (1,390 words) - 16:10, 27 May 2024
synthetase 2, aspartate transcarbamylase, and dihydroorotase) is a trifunctional multi-domain enzyme involved in the first three steps of pyrimidine...
9 KB (1,156 words) - 15:08, 5 January 2024
Mitochondrial DNA depletion syndrome, hepatocerebral form Mitochondrial trifunctional protein deficiency Multiple endocrine neoplasia Munchausen syndrome...
21 KB (1,265 words) - 01:46, 22 December 2023
January 2013) Minson, A. C.; Creaser, E. H. (1969). "Purification of a trifunctional enzyme, catalysing three steps of the histidine pathway, from Neurospora...
28 KB (2,743 words) - 06:38, 11 January 2024
wound-healing accelerant for vesicant-triggered skin lesions. The drug is a trifunctional pharmaceutical composed of covalently linked inhibitors of COX-2, acetylcholinesterase...
31 KB (2,888 words) - 23:31, 28 March 2024
counterpart. Also, it has been found to be a subunit of the peroxisomal trifunctional enzyme (pTFE) and contributes only to minor cleavages of the fatty acid...
26 KB (2,966 words) - 16:30, 21 May 2024