• Thumbnail for Trypanosoma brucei
    Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma that is present in sub-Saharan Africa. Unlike other protozoan...
    107 KB (12,571 words) - 22:59, 24 August 2024
  • Thumbnail for Trypanosoma
    sickness, caused by Trypanosoma brucei, and Chagas disease, caused by Trypanosoma cruzi. The mitochondrial genome of the Trypanosoma, as well as of other...
    19 KB (2,089 words) - 12:26, 16 May 2024
  • Thumbnail for African trypanosomiasis
    caused by the species Trypanosoma brucei. Humans are infected by two types, Trypanosoma brucei gambiense (TbG) and Trypanosoma brucei rhodesiense (TbR)....
    77 KB (7,173 words) - 22:40, 4 September 2024
  • Thumbnail for Trypanosoma evansi
    Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei, Faculty...
    24 KB (2,653 words) - 10:04, 5 August 2024
  • Thumbnail for Trypanosomatida
    Trypanosoma brucei. The three major human diseases caused by trypanosomatids are; African trypanosomiasis (sleeping sickness, caused by Trypanosoma brucei...
    26 KB (2,543 words) - 16:36, 16 July 2024
  • Thumbnail for Variant surface glycoprotein
    belonging to the genus Trypanosoma. This genus is notable for their cell surface proteins. They were first isolated from Trypanosoma brucei in 1975 by George...
    31 KB (3,690 words) - 23:06, 13 August 2024
  • Thumbnail for Melarsoprol
    second-stage disease caused by Trypanosoma brucei rhodesiense when the central nervous system is involved. For Trypanosoma brucei gambiense, eflornithine or...
    18 KB (1,744 words) - 02:47, 5 March 2024
  • Thumbnail for Tsetse fly
    named Trypanosoma brucei brucei. Strains that infected humans were divided into two subspecies based on their different virulences: Trypanosoma brucei gambiense...
    85 KB (8,898 words) - 03:16, 6 September 2024
  • Thumbnail for Trypanosomiasis
    African trypanosomiasis, which is caused by either Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense, threatens some 65 million people in sub-Saharan...
    18 KB (2,061 words) - 20:07, 15 May 2024
  • Thumbnail for Eflornithine
    second-stage sleeping sickness Trypanosoma brucei gambiense. Eflornithine is not effective in the treatment of Trypanosoma brucei rhodesiense due to the parasite's...
    38 KB (3,966 words) - 00:50, 24 July 2024
  • Thumbnail for Suramin
    of first-stage African trypanosomiasis caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense without involvement of central nervous...
    22 KB (2,116 words) - 08:47, 24 July 2024
  • different protozoan parasites. Trypanosoma brucei and Plasmodium falciparum are some of the best studied examples. Trypanosoma brucei, the organism that causes...
    25 KB (3,270 words) - 05:30, 15 April 2024
  • Thumbnail for Winterbottom's sign
    sleeping sickness), a disease caused by the parasites Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. It may be suggestive of cerebral infection...
    3 KB (169 words) - 23:04, 13 August 2024
  • Thumbnail for Orlistat
    its off-targets. Orlistat also shows potential activity against the Trypanosoma brucei parasite. Orlistat prevents approximately 30% of dietary fat from...
    39 KB (3,466 words) - 10:08, 22 May 2024
  • Thumbnail for Kinetoplast
    suggesting that it is bound to some components of the cytoskeleton. In Trypanosoma brucei this cytoskeletal connection is called the tripartite attachment complex...
    12 KB (1,497 words) - 16:26, 17 June 2023
  • African trypanosomiasis due to Trypanosoma brucei gambiense infection. To be used for the treatment of Trypanosoma brucei gambiense infection. To be used...
    67 KB (4,835 words) - 05:59, 17 August 2024
  • Thumbnail for Telomerase
    its own RNA molecule (e.g., with the sequence 3′-CCCAAUCCC-5′ in Trypanosoma brucei) which is used as a template when it elongates telomeres. Telomerase...
    49 KB (5,644 words) - 06:05, 27 April 2024
  • such as the African Sleeping Sickness, caused by the zooflagellate Trypanosoma brucei. Zooflagellates have one or more flagella but do not have plastids...
    1 KB (144 words) - 19:10, 27 March 2024
  • proteins or PARP are proteins developed in the surface coating of Trypanosoma brucei parasites while in their tsetse fly vector. The cell surface of the...
    6 KB (339 words) - 00:14, 15 September 2021
  • Thumbnail for Haptoglobin-related protein
    as part of the trypanolytic factor against the protozoan parasite Trypanosoma brucei thereby providing natural resistance to African sleeping sickness...
    14 KB (1,609 words) - 17:37, 18 April 2024
  • Thumbnail for Intrinsically disordered proteins
    Disordered Region Modulates Ligand Binding in Glutaredoxin 1 from Trypanosoma Brucei". The Journal of Physical Chemistry B. 125 (49): 13366–13375. doi:10...
    52 KB (6,004 words) - 15:08, 6 May 2024
  • Thumbnail for Protozoan infection
    system. African Sleeping Sickness is caused by Trypanosoma brucei rhodensiense and Trypanosoma brucei gambiense, and is transmitted by the tsetse fly...
    32 KB (3,716 words) - 16:28, 15 December 2023
  • and tsetse flies transmit protozoan trypansomes (Trypanosoma brucei gambiense and Trypansoma brucei rhodesiense) which cause African Trypanosomiasis (sleeping...
    8 KB (283 words) - 23:53, 21 July 2024
  • used to treat African trypanosomiasis (sleeping sickness) caused by Trypanosoma brucei gambiense. It is effective against both first and second stage disease...
    21 KB (1,737 words) - 13:31, 23 April 2024
  • Thumbnail for Trypanosoma equiperdum
    "Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei". Proc Natl...
    2 KB (221 words) - 18:02, 12 April 2024
  • Thumbnail for Liberia
    civil war, and bushmeat consumption is now believed to be far higher. Trypanosoma brucei gambiense is endemic in some animal hosts here including both domestic...
    167 KB (14,585 words) - 04:49, 6 September 2024
  • (2014). "Infectious Disease & Antimicrobial Agents - Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense (African Trypanosomiasis)". antimicrobe...
    16 KB (1,856 words) - 11:26, 27 July 2024
  • Thumbnail for David Bruce (microbiologist)
    as Malta fever. In 1894, he discovered a protozoan parasite, named Trypanosoma brucei, as the causative pathogen of nagana (animal trypanosomiasis). Working...
    33 KB (3,932 words) - 08:33, 14 June 2024
  • Thumbnail for Indole-3-acetic acid
    along with tryptophol. This was first observed in rats infected by Trypanosoma brucei gambiense. A 2015 experiment showed that a high-tryptophan diet can...
    26 KB (2,766 words) - 00:37, 15 May 2024
  • Thumbnail for Eradication of infectious diseases
    treatment is continued. The WHO aims to eliminate transmission of the Trypanosoma brucei gambiense parasite by 2030, though it acknowledges that this goal...
    82 KB (8,409 words) - 19:33, 29 August 2024