Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene. SYK, along with ZAP70, is...
18 KB (2,083 words) - 06:18, 25 December 2023
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions...
43 KB (5,251 words) - 10:44, 24 June 2024
the 90 unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown...
28 KB (3,078 words) - 07:46, 3 June 2024
Tyrosine-protein kinase CSK also known as C-terminal Src kinase is an enzyme that, in humans, is encoded by the CSK gene. This enzyme phosphorylates tyrosine...
8 KB (977 words) - 00:09, 6 October 2021
Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in...
27 KB (2,841 words) - 20:02, 9 December 2024
donor, such as ATP, to tyrosine residues in proteins. Non-receptor tyrosine kinases are a subgroup of protein family tyrosine kinases, enzymes that can transfer...
21 KB (2,717 words) - 01:53, 18 December 2024
A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that...
23 KB (750 words) - 23:26, 13 August 2024
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
21 KB (2,648 words) - 12:12, 26 July 2024
Tyrosine-protein kinase BLK, also known as B lymphocyte kinase, is a non-receptor tyrosine kinase that in humans is encoded by the BLK gene. It is of...
7 KB (847 words) - 20:21, 9 January 2024
Tyrosine-protein kinase receptor UFO is a protein that in human is encoded by the AXL gene. The gene was initially designated as UFO, in allusion to the...
19 KB (2,361 words) - 14:11, 26 September 2024
Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They...
9 KB (974 words) - 14:46, 22 June 2024
Tyrosin-protein kinase Lck (or lymphocyte-specific protein tyrosine kinase) is a 56 kDa protein that is found inside lymphocytes and encoded in the human...
36 KB (4,466 words) - 12:30, 11 May 2024
Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded...
48 KB (5,299 words) - 01:24, 9 March 2024
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor,...
39 KB (4,391 words) - 05:30, 23 October 2024
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. It is a member of the Janus kinase family and has been implicated in signaling...
28 KB (3,166 words) - 19:57, 8 August 2024
Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. TYK2 was the first member of the JAK family that was...
25 KB (2,850 words) - 23:00, 12 November 2023
specific and tyrosine specific. Protein kinase function has been evolutionarily conserved from Escherichia coli to Homo sapiens. Protein kinases play a role...
17 KB (1,566 words) - 18:56, 22 September 2024
Tyrosine-protein kinase JAK3 is a tyrosine kinase enzyme that in humans is encoded by the JAK3 gene. Janus kinase 3 is a tyrosine kinase that belongs to...
41 KB (5,166 words) - 16:45, 28 January 2023
TRK1-transforming tyrosine kinase protein is a protein that in humans is encoded by the NTRK1 gene. This gene encodes a member of the neurotrophic tyrosine kinase receptor...
28 KB (3,328 words) - 15:54, 29 October 2024
Leukocyte receptor tyrosine kinase is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK...
7 KB (857 words) - 08:38, 26 December 2023
Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene. The protein encoded by this gene has amino acid...
9 KB (1,177 words) - 01:33, 17 April 2022
PTK2 (redirect from PTK2 protein tyrosine kinase 2)
PTK2 protein tyrosine kinase 2 (PTK2), also known as focal adhesion kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. PTK2 is a...
41 KB (4,724 words) - 09:43, 11 December 2023
Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...
10 KB (1,215 words) - 14:38, 22 September 2024
Chapman code Tyrosine-protein kinase SYK, an enzyme Sachdev-Ye-Kitaev model This disambiguation page lists articles associated with the title SYK. If an internal...
258 bytes (62 words) - 08:50, 16 March 2022
ZAP70 (redirect from Zap-70 protein-tyrosine kinase)
weight is 70 kDa, and it is a member of the protein-tyrosine kinase family and is a close homolog of SYK. SYK and ZAP70 share a common evolutionary origin...
23 KB (2,769 words) - 14:27, 11 December 2023
(disease-modifying antirheumatic drugs), and they are a subclass of tyrosine kinase inhibitors. They work by modifying the immune system via cytokine activity...
37 KB (3,296 words) - 02:08, 8 November 2024
Tyrosine-protein kinase Yes is a non-receptor tyrosine kinase that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi...
8 KB (1,028 words) - 11:58, 15 November 2024
MuSK (for Muscle-Specific Kinase) is a receptor tyrosine kinase required for the formation and maintenance of the neuromuscular junction. It is activated...
6 KB (695 words) - 20:14, 28 January 2023
Soluble fms-like tyrosine kinase-1 (sFlt-1 or sVEGFR-1) is a tyrosine kinase protein with antiangiogenic properties. A non-membrane associated splice...
19 KB (2,341 words) - 00:54, 8 November 2023
receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase is a protein that...
30 KB (3,901 words) - 17:05, 28 November 2024