U.S. Route 4 (US 4) is a 253-mile-long (407 km) United States Numbered Highway that runs from East Greenbush, New York, in the west to Portsmouth, New...

U.S. Route 4 in New Hampshire runs for 106.834 miles (171.933 km) across the central and southern part of the state, stretching from Lebanon on the Connecticut...

U.S. Route 66 or U.S. Highway 66 (US 66 or Route 66) was one of the original highways in the United States Numbered Highway System. It was established...

U.S. Route 4 (US 4) in the U.S. state of Vermont extends for 66.059 miles (106.312 km) between the New York state line at Fair Haven and the New Hampshire...

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 111 (US 111) was a U.S. Highway that extended from Baltimore, Maryland north to the Harrisburg, Pennsylvania area. It replaced part of the...

U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching 3,019 miles (4,859 km) from Interstate 80 (I-80)...

U.S. Route 310 (US 310) is a spur of historic U.S. Route 10, now Interstate 90. It runs for 108 miles (174 km) from Laurel, Montana, to Greybull, Wyoming...

U.S. Route 31E (US 31E) is the eastern parallel route for U.S. Highway 31 from Nashville, Tennessee, to Louisville, Kentucky. US 31E begins as the Ellington...

U.S. Route 460 (US 460) is an auxiliary route of U.S. Route 60. It currently runs for 655 miles (1,054 km) from Norfolk, Virginia, at its parent route...

U.S. Route 165 is a north–south United States highway spur of U.S. Highway 65. It currently runs for 412 miles (663 km) from U.S. Route 90 in Iowa, Louisiana...

U.S. Route 65 (US 65) is a north–south United States highway in the southern and midwestern United States. The southern terminus of the route is at U...

U.S. Route 641 (US 641) is a U.S. Route in Tennessee and Kentucky. It runs for 165.45 miles (266.27 km) from US 64 south of Clifton, Tennessee to an intersection...

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with...

U.S. Route 283 is a spur of U.S. Route 83. It currently runs for 731 miles (1,175 km) from Brady, Texas at U.S. Route 87 to Lexington, Nebraska at U.S...

U.S. Route 276 (US 276) is a United States highway that runs for 106.4 miles (171.2 km) from Mauldin, South Carolina to Cove Creek, North Carolina. It...

U.S. Route 385 (US 385) is a spur of U.S. Route 85 that runs for 1,206 miles (1,941 km) from Deadwood, South Dakota to Big Bend National Park in Texas...

U.S. Route 4 (US 4) is a part of the United States Numbered Highway System that runs from East Greenbush, New York, to Portsmouth, New Hampshire. In the...

U.S. Route 167 is a north-south United States Highway within the U.S. states of Louisiana and Arkansas. It runs for 500 miles (800 km) from Ash Flat, Arkansas...

connects U.S. Route 62 U.S. Route 75 (US 62/US 75) in Henryetta with U.S. Route 64 (US 64) in Warner. The highway no longer meets the former route of its...

U.S. Route 78 (US 78) is an east–west United States Numbered Highway that runs for 843.3 miles (1,357.2 km) from Cash, Arkansas, to Charleston, South...

U.S. Route 412 is an east–west United States highway, first commissioned in 1982. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west...

U.S. Route 6 (US 6) or U.S. Highway 6 (US 6), also called the Grand Army of the Republic Highway, honoring the American Civil War veterans association...

U.S. Route 191 (US 191) is a north–south highway in the Western United States and a spur of parent route U.S. Route 91 that has two segments. The southern...

U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

U.S. Route 59 (US 59) is a north–south United States highway (though it was signed east–west in parts of Texas). A latecomer to the U.S. numbered route...

U.S. Route 58 (US 58) is an east–west U.S. Highway that runs for 508 miles (818 km) from U.S. Route 25E just northwest of Harrogate, Tennessee, to U.S...

U.S. Route 82 (US 82) is an east–west United States highway in the Southern United States. Created on July 1, 1931 across central Mississippi and southern...