Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step in the ubiquitination reaction...
5 KB (605 words) - 04:25, 28 November 2023
A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
24 KB (2,755 words) - 04:56, 29 September 2024
conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. The...
97 KB (11,029 words) - 03:48, 27 October 2024
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a...
9 KB (1,051 words) - 15:40, 31 December 2023
CDC34 (redirect from Ubiquitin-conjugating enzyme E2 R1)
humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family, which catalyzes the...
12 KB (1,341 words) - 16:32, 14 October 2024
Ubiquitin conjugating enzyme E2 Q2 is a protein that in humans is encoded by the UBE2Q2 gene. GRCh38: Ensembl release 89: ENSG00000140367 – Ensembl, May...
4 KB (587 words) - 21:58, 15 August 2023
SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene. It is also sometimes referred to as "ubiquitin conjugating enzyme E2I"...
24 KB (2,840 words) - 09:41, 17 February 2023
Ubiquitin conjugating enzyme E2 F (putative) is a protein that in humans is encoded by the UBE2F gene. GRCh38: Ensembl release 89: ENSG00000184182 – Ensembl...
690 bytes (97 words) - 21:54, 3 March 2023
UBE3A (redirect from Ubiquitin protein ligase E3A)
Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene. This...
13 KB (1,508 words) - 10:38, 21 December 2023
Ubiquitin-conjugating enzyme E2 B is a protein that in humans is encoded by the UBE2B gene. The modification of proteins with ubiquitin is an important...
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is then transferred to an E2 ubiquitin-conjugating enzyme before being conjugated to the target protein via an E3 ubiquitin ligase. There exists a multitude...
47 KB (5,731 words) - 11:29, 22 June 2024
Ubiquitin-conjugating enzyme E2 A is a protein that in humans is encoded by the UBE2A gene. The modification of proteins with ubiquitin is an important...
10 KB (1,140 words) - 10:57, 19 February 2024
marrow stem cells of patients presenting with VEXAS. E: The E1 ubiquitin conjugating enzyme encoded by the UBA1 gene is mutated in patients. X: The mutated...
16 KB (1,094 words) - 16:23, 15 July 2024
Ubiquitin-conjugating enzyme E2 C is a protein that in humans is encoded by the UBE2C gene. The modification of proteins with ubiquitin is an important...
6 KB (806 words) - 10:56, 17 October 2022
Ubiquitin-conjugating enzyme E2 H is a protein that in humans is encoded by the UBE2H gene. The modification of proteins with ubiquitin is an important...
6 KB (717 words) - 06:25, 13 May 2024
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene. The modification of proteins with ubiquitin is an important...
9 KB (1,070 words) - 02:16, 25 March 2022
NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene. The modification of proteins with ubiquitin is an important cellular...
7 KB (788 words) - 01:42, 17 April 2022
Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the UBE2D2 gene. The modification of proteins with ubiquitin is an important...
11 KB (1,291 words) - 10:20, 24 December 2023
Ubiquitin-conjugating enzyme E2 variant 1, also known as Kua-UEV, is a human gene. The Kua-UEV mRNA is an infrequent but naturally occurring co-transcribed...
6 KB (702 words) - 06:30, 7 January 2024
Ubiquitin-conjugating enzyme E2 J1 is a protein that in humans is encoded by the UBE2J1 gene. The modification of proteins with ubiquitin is an important...
5 KB (596 words) - 23:37, 3 March 2023
ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination, although it relies on its own enzymes...
4 KB (589 words) - 11:55, 8 October 2024
Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene. The protein encoded by this gene belongs to the ubiquitin-conjugating...
8 KB (982 words) - 09:40, 18 August 2023
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3), also called UBCH7, is a protein that in humans is encoded by the UBE2L3 gene. As an E2 enzyme, UBE2L3 participates...
18 KB (2,124 words) - 03:07, 26 October 2023
Proteasome (redirect from Ubiquitin proteosome system)
protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are...
105 KB (12,670 words) - 08:02, 23 August 2024
Ubiquitin-fold modifier conjugating enzyme 1 is a protein that in humans is encoded by the UFC1 gene. UFC1 is an E2-like conjugating enzyme for ubiquitin-fold...
3 KB (489 words) - 11:31, 17 October 2022
Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene. The modification of proteins with ubiquitin is an...
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to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by...
4 KB (491 words) - 19:54, 13 October 2022
SUMO protein (redirect from Small ubiquitin-like modifier)
E1 enzyme (SUMO Activating Enzyme (SAE)) which is a heterodimer (subunits SAE1 and SAE2). It is then passed to an E2, which is a conjugating enzyme (Ubc9)...
22 KB (2,759 words) - 19:59, 23 October 2024
Ubiquitin-conjugating enzyme E2 D1 is a protein that in humans is encoded by the UBE2D1 gene. The modification of proteins with ubiquitin is an important...
13 KB (1,507 words) - 10:19, 24 December 2023
Ubiquitin-conjugating enzyme E2 variant 2 is a protein that in humans is encoded by the UBE2V2 gene. Ubiquitin-conjugating enzyme E2 variant proteins...
13 KB (1,677 words) - 01:28, 9 April 2022