Protein VPRBP is a protein that in humans is encoded by the VPRBP gene. VPRBP has been shown to interact with Merlin. GRCh38: Ensembl release 89: ENSG00000145041...
5 KB (569 words) - 22:25, 3 March 2023
(VprBP) is a 1,507-amino-acid human protein that contains conserved domains, including YXXY repeats, the Lis homology motif, and WD40 repeats. VprBP acts...
5 KB (684 words) - 05:08, 13 September 2023
6782-6795.2001. PMC 99856. PMID 11564863. Huang J, Chen J (July 2008). "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation"...
11 KB (1,415 words) - 11:53, 15 November 2024
to interact with: CUL4A, DDB1, EZR, HGS, MED28, RIT1, SDCBP, SPTBN1, and VPRBP. GRCh38: Ensembl release 89: ENSG00000186575 – Ensembl, May 2017 GRCm38:...
12 KB (1,408 words) - 08:42, 20 October 2024
ubiquitination and degradation DCAF1 is also named VPRBP due to its interaction with HIV-1 protein Vpr. Although DCAF1/VPRBP appears to have a crucial function in...
36 KB (4,418 words) - 03:28, 3 December 2023
1074/jbc.M708473200. PMC 2431063. PMID 18303015. Huang J, Chen J (July 2008). "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation"...
5 KB (639 words) - 17:35, 11 October 2022
the same mechanism. Essentially, HIV proteins such as Vpr and Vpx bind to VPRBP (a DDB1-binding substrate receptor protein) and induce the ubiquitination...
23 KB (2,948 words) - 23:56, 9 September 2023