DNA repair protein XRCC2 is a protein that in humans is encoded by the XRCC2 gene. This gene encodes a member of the RecA/Rad51-related protein family...
15 KB (1,849 words) - 15:34, 5 January 2024
(RAD51C), FANCP (SLX4), FANCQ (XPF), FANCS (BRCA1), FANCT (UBE2T), FANCU (XRCC2), FANCV (REV7), and FANCW (RFWD3). FANCB is the one exception to FA being...
37 KB (4,140 words) - 08:44, 11 April 2024
several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze...
11 KB (1,334 words) - 11:51, 30 July 2024
(2017-11-01). "Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks". Journal of Medical...
5 KB (590 words) - 23:59, 21 February 2024
RAD51, including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence identity with RAD51...
24 KB (2,939 words) - 19:12, 4 January 2024
RAD51, consisting of RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 form a complex called the BCDX2 complex (see Figure: Recombinational repair...
72 KB (7,870 words) - 07:10, 16 August 2024
O43592 18400 XPR1 HGNC:12827 Q9UBH6 18401 XRCC1 HGNC:12828 P18887 18402 XRCC2 HGNC:12829 O43543 18403 XRCC3 HGNC:12830 O43542 18404 XRCC4 HGNC:12831 Q13426...
242 KB (17 words) - 23:17, 27 April 2024
RAD51, including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence identity with RAD51...
13 KB (1,745 words) - 05:58, 29 April 2023
binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization...
18 KB (1,567 words) - 01:04, 10 March 2024
recA-like genes have been identified: Rad51, Rad51L1/B, Rad51L2/C, Rad51L3/D, XRCC2, XRCC3, and DMC1/Lim15. All of these proteins, with the exception of meiosis-specific...
48 KB (5,526 words) - 16:55, 15 July 2024
binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization...
34 KB (4,130 words) - 03:55, 5 August 2024
FEN1, H2AFX, MCM6 MLH1 P53, RAD51L3, RAD51, RPA1, TOP3A, TP53BP1, WRN, and XRCC2. GRCh38: Ensembl release 89: ENSG00000197299 – Ensembl, May 2017 GRCm38:...
21 KB (2,561 words) - 17:00, 27 August 2024
RAD51, consisting of RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 form a complex called the BCDX2 complex. This complex participates in RAD51...
23 KB (3,013 words) - 01:47, 11 April 2024
laboratory described the high resolution structure of the RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex using cryo-electron microscopy, and defined its function...
11 KB (1,292 words) - 13:00, 6 August 2024
which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1...
8 KB (1,051 words) - 01:49, 4 March 2023
binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization...
24 KB (2,538 words) - 12:38, 28 August 2024
binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization...
21 KB (2,456 words) - 00:57, 27 January 2024
sequencing technology to fast-track the discovery of a breast cancer risk gene, XRCC2. DARPA, the US military's advanced research agency, offers a US$2 million...
397 KB (38,856 words) - 16:19, 3 August 2024
binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization...
12 KB (1,374 words) - 11:42, 15 January 2024