Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during...

cancer research and provided the basis for the notion of the somatic evolution of cancer. In the 1980s, Vogelstein developed new experimental approaches...

Maynard Smith. His work spans a wide range of topics, from the somatic evolution of cancer to the origins of language and prelife. Nowak has authored over...

organism. Many cancers are the result of accumulated somatic mutations. The term somatic generally refers to the cells of the body, in contrast to the...

Medicine portal Epidemiology of cancer List of biological development disorders Pleomorphism Somatic evolution in cancer "neoplasm". Lexico UK English Dictionary...

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the...

dominate the growing tumor as other cells are out-competed (see: somatic evolution in cancer). Because of these selective properties, the majority of cells...

Somatic Experiencing (SE) is a form of alternative therapy aimed at treating trauma and stress-related disorders, such as PTSD. The primary goal of SE...

accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt these orderly processes by interfering...

Somatics is a field within bodywork and movement studies which emphasizes internal physical perception and experience. The term is used in movement therapy...

tumor evolution is an important topic of current cancer research. Somatic mosaicism occurs in virtually all cancer cells, including trisomy 12 in chronic...

anti-cancer drugs. However, somatic mutations tend to cluster in a limited number of signalling pathways, which are potential treatment targets. Cancers are...

Evolution is the change in the heritable characteristics of biological populations over successive generations. It occurs when evolutionary processes such...

Human somatic variations are somatic mutations (mutations that occur in somatic cells) both at early stages of development and in adult cells. These variations...

current cancer research. All malignant cancers are fundamentally governed by Darwinian dynamics of the somatic evolution in cancer. Malignant cancers are...

the capacity of phenotypic evolution. The somatic mutation theory of ageing states that accumulation of mutations in somatic cells is the primary cause...

plants do not develop cancer. In some multicellular groups, which are called Weismannists, a separation between a sterile somatic cell line and a germ...

cancer cells have a low metastatic potential and that there are rare cells that develop the ability to metastasize through the development of somatic...

such as an oncovirus. The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare. This...

"Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource". Genome Biology...

whole cancer genome sequencing in identifying somatic mutations and the importance of parallel sequencing of normal and tumor cell genomes. In 2011, the...

outcompete other tumor cells, better known as the somatic evolution model. The clonal evolution model, which occurs in both the CSC model and stochastic model,...

part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity...

the air." Bowler 2013, p. 21 Steele, E. J. (2016). "Somatic hypermutation in immunity and cancer: Critical analysis of strand-biased and codon-context...

number of chromosomes in the somatic cells of an individual or a species is called the somatic number and is designated 2n. In the germ-line (the sex...

DK; Debets AJM; de Visser JAGM; Hoekstra RF (2008). "The social evolution of somatic fusion". BioEssays. 30 (11–12): 1193–1203. doi:10.1002/bies.20840...

rapidly to produce all of the cells in the body, causing this mutation to be present in every somatic and germline cell in the offspring; this is also known...

that allows cancer cells to grow in vitro for decades. Telomerase activity is necessary to preserve many cancer types and is inactive in somatic cells, creating...

cause of many types of cancer. In such cases the genetic duplication occurs in a somatic cell and affects only the genome of the cancer cells themselves, not...

parasitology, somatic evolution in cancer, mismatch theory, and senescence. In 2014 and 2016, Brinkman attended the Science of Consciousness conference in Tucson...