• Thumbnail for 1,4-Dihydropyridine
    1,4-Dihydropyridine (DHP) is an organic compound with the formula CH2(CH=CH)2NH. The parent compound is uncommon, but derivatives of 1,4-dihydropyridine...
    4 KB (302 words) - 18:46, 1 August 2024
  • Dihydropyridine calcium channel blockers are derivatives of 1,4-dihydropyridine that are used as L-type calcium channel blockers. They are used in the...
    13 KB (904 words) - 11:13, 11 August 2024
  • was reported in 1881 by Arthur Rudolf Hantzsch. A 1,4-dihydropyridine dicarboxylate is also called a 1,4-DHP compound or a Hantzsch ester. These compounds...
    12 KB (1,230 words) - 14:25, 26 September 2024
  • Thumbnail for Hantzsch ester
    (C2H5). It is a light yellow solid. The compound is an example of a 1,4-dihydropyridine. It is named after Arthur Rudolf Hantzsch who described its synthesis...
    3 KB (248 words) - 05:17, 22 August 2024
  • Thumbnail for Nifedipine
    (January 1972). "[Pharmacology of 4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (Nifedipine, BAY a 1040)]"....
    22 KB (2,033 words) - 05:46, 15 October 2024
  • Thumbnail for Brooker's merocyanine
    Brooker's merocyanine (1-methyl-4-[(oxocyclohexadienylidene)ethylidene]-1,4-dihydropyridine, MOED) is an organic dye belonging to the class of merocyanines....
    8 KB (762 words) - 11:27, 31 August 2024
  • Thumbnail for Cilnidipine
    Cilnidipine (category Dihydropyridines)
    Matsuoka H, Takishita S (December 2000). "Effects of cilnidipine, a novel dihydropyridine calcium antagonist, on autonomic function, ambulatory blood pressure...
    7 KB (658 words) - 11:59, 29 September 2024
  • Thumbnail for Pyridine
    yields a mixture of 1,4-dihydropyridine, 1,2-dihydropyridine, and 2,5-dihydropyridine. Selective synthesis of 1,4-dihydropyridine is achieved in the presence...
    76 KB (7,667 words) - 19:03, 15 September 2024
  • Thumbnail for Nimodipine
    Nimodipine (category Dihydropyridines)
    "Unsymmetrische 1,4-Dihydropyridincarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimitell I [Asymmetrical 1,4-dihydropyridine carboxylic...
    16 KB (1,367 words) - 11:57, 29 September 2024
  • Thumbnail for Amlodipine
    Amlodipine (category Dihydropyridines)
    their diameter). It is a long-acting calcium channel blocker of the dihydropyridine type. Amlodipine was patented in 1982, and approved for medical use...
    45 KB (4,043 words) - 00:40, 30 September 2024
  • Thumbnail for Barnidipine
    Barnidipine (category Dihydropyridines)
    of hypertension. Barnidipine is a pure S,S isomer, a lipophilic 1,4-dihydropyridine calcium channel blocker, which, like other compounds in the class...
    3 KB (131 words) - 11:56, 29 September 2024
  • Thumbnail for Calciseptine
    blockers of the L-type channel were small organic molecules like 1,4-dihydropyridines. It was suggested that polypeptide inhibitors could be found in snake...
    25 KB (3,173 words) - 00:01, 27 October 2023
  • Thumbnail for Levamlodipine
    Levamlodipine (category Dihydropyridines)
    PMID 2434785. S2CID 40257612. Goldmann S, Stoltefuss J (December 1991). "1,4-Dihydropyridines: Effects of Chirality and Conformation on the Calcium Antagonist...
    12 KB (1,198 words) - 08:14, 9 September 2024
  • Thumbnail for CYP3A4
    M, Yamazaki H, Yokoi T (October 2000). "Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison...
    80 KB (7,794 words) - 21:26, 15 July 2024
  • the closely related P/Q-type channel blocked by ω-agatoxins, and the dihydropyridine-sensitive L-type channels responsible for excitation-contraction coupling...
    28 KB (3,091 words) - 08:22, 19 October 2024
  • Thumbnail for Felodipine
    Felodipine (category Dihydropyridines)
    amlodipine 5, and verapamil 0.2.: 172  Felodipine is a member of the 1,4-dihydropyridine class of calcium channel blockers.: 20–21  It is a racemic mixture...
    12 KB (949 words) - 17:30, 14 July 2024
  • Thumbnail for Manidipine
    Manidipine (category Dihydropyridines)
    Sohda, Takashi; Kawamatsu, Yutaka; Nagaoka, Akinobu (1985). "New 1,4-dihydropyridine derivatives with potent and long-lasting hypotensive effect.". CHEMICAL...
    6 KB (419 words) - 11:56, 29 September 2024
  • Thumbnail for Lercanidipine
    Lercanidipine (category Dihydropyridines)
    antihypertensive (blood pressure lowering) drug. It belongs to the dihydropyridine class of calcium channel blockers, which work by relaxing and opening...
    15 KB (1,415 words) - 11:56, 29 September 2024
  • Thumbnail for 2,6-Lutidine
    an ammonia source to give a bis(carboxy ester) of a 2,6-dimethyl-1,4-dihydropyridine, which, after hydrolysis, undergoes decarboxylation. It is produced...
    7 KB (610 words) - 19:05, 26 July 2024
  • Thumbnail for Nicardipine
    Nicardipine (category Dihydropyridines)
    medication used to treat high blood pressure and angina. It belongs to the dihydropyridine class of calcium channel blockers (CCBs). It is also used for Raynaud's...
    5 KB (294 words) - 11:56, 29 September 2024
  • Thumbnail for Pranidipine
    Pranidipine (category Dihydropyridines)
    channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group. Jin Yang; Keisuke Fukuo; Shigeto Morimoto; Tadaaki Niinobu;...
    3 KB (62 words) - 11:57, 29 September 2024
  • Thumbnail for Nitrendipine
    Nitrendipine (category Dihydropyridines)
    Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure...
    8 KB (670 words) - 11:57, 29 September 2024
  • Thumbnail for Isradipine
    Isradipine (category Dihydropyridines)
    (tradenames DynaCirc, Prescal) is a calcium channel blocker of the dihydropyridine class. It is usually prescribed for the treatment of high blood pressure...
    9 KB (660 words) - 00:05, 21 September 2024
  • Thumbnail for Benidipine
    Benidipine (category Dihydropyridines)
    Benidipine is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). It is a triple L-, T-, and N-type calcium...
    4 KB (183 words) - 10:14, 30 September 2024
  • Thumbnail for CACNG1
    proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that...
    4 KB (616 words) - 18:34, 22 August 2024
  • Thumbnail for L-type calcium channel
    experimentation, it was found that HVA channels were blocked by derivatives of 1,4-dihydropyridine (DHPs). Using DHPs, it was found that HVA channels were specific...
    17 KB (2,004 words) - 01:57, 7 August 2024
  • Thumbnail for Lacidipine
    Lacidipine (category Dihydropyridines)
    Diethyl 4-{o-[(E)-2-tert-butoxycarbonylethenyl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate CAS Number 103890-78-4 PubChem CID 5311217 ChemSpider...
    3 KB (58 words) - 21:39, 20 December 2023
  • Thumbnail for Riodipine
    Riodipine (category Dihydropyridines)
    Preferred IUPAC name Dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Identifiers CAS Number 71653-63-9 Y 3D model (JSmol)...
    2 KB (40 words) - 10:07, 9 January 2023
  • Thumbnail for Clevidipine
    Clevidipine (category Dihydropyridines)
    Clevidipine (INN, trade name Cleviprex) is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is...
    15 KB (1,607 words) - 15:59, 8 November 2023
  • of 1,2,3,4-Tetrahydropyridines and Piperidines from Hantzsch-Type 1,4-Dihydropyridines". Synthesis. 1985 (2): 210–212. doi:10.1055/s-1985-31160. Loim, N...
    13 KB (1,452 words) - 16:57, 15 August 2024