1,4-Dihydropyridine (DHP) is an organic compound with the formula CH2(CH=CH)2NH. The parent compound is uncommon, but derivatives of 1,4-dihydropyridine...
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Dihydropyridine calcium channel blockers are derivatives of 1,4-dihydropyridine that are used as L-type calcium channel blockers. They are used in the...
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was reported in 1881 by Arthur Rudolf Hantzsch. A 1,4-dihydropyridine dicarboxylate is also called a 1,4-DHP compound or a Hantzsch ester. These compounds...
12 KB (1,230 words) - 14:25, 26 September 2024
Hantzsch ester (redirect from Hantzsch dihydropyridine synthesis)
(C2H5). It is a light yellow solid. The compound is an example of a 1,4-dihydropyridine. It is named after Arthur Rudolf Hantzsch who described its synthesis...
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Nifedipine (redirect from 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate)
(January 1972). "[Pharmacology of 4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (Nifedipine, BAY a 1040)]"....
22 KB (2,033 words) - 05:46, 15 October 2024
Brooker's merocyanine (1-methyl-4-[(oxocyclohexadienylidene)ethylidene]-1,4-dihydropyridine, MOED) is an organic dye belonging to the class of merocyanines....
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Cilnidipine (category Dihydropyridines)
Matsuoka H, Takishita S (December 2000). "Effects of cilnidipine, a novel dihydropyridine calcium antagonist, on autonomic function, ambulatory blood pressure...
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yields a mixture of 1,4-dihydropyridine, 1,2-dihydropyridine, and 2,5-dihydropyridine. Selective synthesis of 1,4-dihydropyridine is achieved in the presence...
76 KB (7,667 words) - 19:03, 15 September 2024
Nimodipine (category Dihydropyridines)
"Unsymmetrische 1,4-Dihydropyridincarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimitell I [Asymmetrical 1,4-dihydropyridine carboxylic...
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Amlodipine (category Dihydropyridines)
their diameter). It is a long-acting calcium channel blocker of the dihydropyridine type. Amlodipine was patented in 1982, and approved for medical use...
45 KB (4,043 words) - 00:40, 30 September 2024
Barnidipine (category Dihydropyridines)
of hypertension. Barnidipine is a pure S,S isomer, a lipophilic 1,4-dihydropyridine calcium channel blocker, which, like other compounds in the class...
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blockers of the L-type channel were small organic molecules like 1,4-dihydropyridines. It was suggested that polypeptide inhibitors could be found in snake...
25 KB (3,173 words) - 00:01, 27 October 2023
Levamlodipine (category Dihydropyridines)
PMID 2434785. S2CID 40257612. Goldmann S, Stoltefuss J (December 1991). "1,4-Dihydropyridines: Effects of Chirality and Conformation on the Calcium Antagonist...
12 KB (1,198 words) - 08:14, 9 September 2024
M, Yamazaki H, Yokoi T (October 2000). "Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison...
80 KB (7,794 words) - 21:26, 15 July 2024
the closely related P/Q-type channel blocked by ω-agatoxins, and the dihydropyridine-sensitive L-type channels responsible for excitation-contraction coupling...
28 KB (3,091 words) - 08:22, 19 October 2024
Felodipine (category Dihydropyridines)
amlodipine 5, and verapamil 0.2.: 172 Felodipine is a member of the 1,4-dihydropyridine class of calcium channel blockers.: 20–21 It is a racemic mixture...
12 KB (949 words) - 17:30, 14 July 2024
Manidipine (category Dihydropyridines)
Sohda, Takashi; Kawamatsu, Yutaka; Nagaoka, Akinobu (1985). "New 1,4-dihydropyridine derivatives with potent and long-lasting hypotensive effect.". CHEMICAL...
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Lercanidipine (category Dihydropyridines)
antihypertensive (blood pressure lowering) drug. It belongs to the dihydropyridine class of calcium channel blockers, which work by relaxing and opening...
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an ammonia source to give a bis(carboxy ester) of a 2,6-dimethyl-1,4-dihydropyridine, which, after hydrolysis, undergoes decarboxylation. It is produced...
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Nicardipine (category Dihydropyridines)
medication used to treat high blood pressure and angina. It belongs to the dihydropyridine class of calcium channel blockers (CCBs). It is also used for Raynaud's...
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Pranidipine (category Dihydropyridines)
channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group. Jin Yang; Keisuke Fukuo; Shigeto Morimoto; Tadaaki Niinobu;...
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Nitrendipine (category Dihydropyridines)
Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure...
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Isradipine (category Dihydropyridines)
(tradenames DynaCirc, Prescal) is a calcium channel blocker of the dihydropyridine class. It is usually prescribed for the treatment of high blood pressure...
9 KB (660 words) - 00:05, 21 September 2024
Benidipine (category Dihydropyridines)
Benidipine is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). It is a triple L-, T-, and N-type calcium...
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proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that...
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experimentation, it was found that HVA channels were blocked by derivatives of 1,4-dihydropyridine (DHPs). Using DHPs, it was found that HVA channels were specific...
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Lacidipine (category Dihydropyridines)
Diethyl 4-{o-[(E)-2-tert-butoxycarbonylethenyl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate CAS Number 103890-78-4 PubChem CID 5311217 ChemSpider...
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Riodipine (category Dihydropyridines)
Preferred IUPAC name Dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Identifiers CAS Number 71653-63-9 Y 3D model (JSmol)...
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Clevidipine (category Dihydropyridines)
Clevidipine (INN, trade name Cleviprex) is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is...
15 KB (1,607 words) - 15:59, 8 November 2023
of 1,2,3,4-Tetrahydropyridines and Piperidines from Hantzsch-Type 1,4-Dihydropyridines". Synthesis. 1985 (2): 210–212. doi:10.1055/s-1985-31160. Loim, N...
13 KB (1,452 words) - 16:57, 15 August 2024