2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB1 receptor and the primary endogenous ligand for the CB2 receptor...

(Δ8-THC), through intracellular CB1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain[citation needed][dubious...

the most known active component of cannabis. Endocannabinoid 2-arachidonoylglycerol (2-AG), which was found to be two and three orders of magnitude more...

neurotransmitters that include lipids, such as anandamide and 2-arachidonoylglycerol (2-AG); plant phytocannabinoids, such as docosatetraenoylethanolamide...

away from achieving that outcome. It is the endocannabinoid, 2-Arachidonoylglycerol (2-AG: C23H38O4; 20:4, ω-6) that shape accumbal encoding of cue-motivated...

(ECs) such as anandamide (N-arachidonoylethanolamide; AEA) and 2-arachidonoylglycerol (2-AG) via a retrograde signaling process in which these compounds...

endocannabinoid 2-arachidonoylglycerol (2-AG). It converts monoacylglycerols to the free fatty acid and glycerol. The contribution of MAGL to total brain 2-AG hydrolysis...

Several monoglycerides are pharmacologically active (e.g. 2-oleoylglycerol, 2-arachidonoylglycerol). Industrial production is primarily achieved by a glycerolysis...

portal Cannabinoids 11-Hydroxy-THC, metabolite of THC Anandamide, 2-Arachidonoylglycerol, endogenous cannabinoid agonists Tetrahydrocannabinol Cannabidiol...

formation of the two main endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG). * Anandamide (AEA: C22H37NO2; 20:4,n-6) is an N-acylethanolamine...

PPARα. 2-Arachidonoylglycerol Hanus, L.; Abu-Lafi, S.; Fride, E.; Breuer, A.; Vogel, Z.; Shalev, D.; Kustanovich, I.; Mechoulam, R. (2001). "2-Arachidonyl...

cannabis-derived compounds in vivo. Both THC and CBN activate the CB1 (Ki = 211.2 nM) and CB2 (Ki = 126.4 nM) receptors. Each compound acts as a low affinity...

(AEA: C22H37NO2; 20:4, ω-6) besides other N-acylethanolamines and 2-Arachidonoylglycerol (2-AG: C23H38O4; 20:4, ω-6), respectively, therefore, it can also...

Δ9-THC itself." Tetrahydrocannabiphorol has a reported binding affinity of 1.2 nM at CB1, approximately 33 times that of Δ9-THC (40 nM at CB1). THCP was...

Hydra and leech), but were secondarily lost in the Ecdysozoa, and 2-Arachidonoylglycerol (2-AG). These amides conceptually can be formed from a fatty acid...

portal Cannabinoids 11-Hydroxy-THC, metabolite of THC Anandamide, 2-Arachidonoylglycerol, endogenous cannabinoid agonists Cannabidiol (CBD) Cannabinol (CBN)...

cannabinoids). The principal endogenous ligand for the CB2 receptor is 2-Arachidonoylglycerol (2-AG). CB2 was cloned in 1993 by a research group from Cambridge...

ethanolamide (AEA; anandamide) 2-Arachidonoylglycerol (2-AG) 2-Arachidonyl glyceryl ether (2-AGE; noladin ether) 2-Oleoylglycerol (2-OG) N-Arachidonoyl dopamine...

responsible for degrading the endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL184 JNJ-42165279 Long JZ, Nomura DK, Vann...

of paracetamol. Endocannabinoid transporters for anandamide and 2-arachidonoylglycerol include the heat shock proteins (Hsp70s) and fatty acid binding...

polypeptide (GIP) levels following administration to the small intestine. 2-Arachidonoylglycerol JZL184 Dinh, T. P.; Carpenter, D.; Leslie, F. M.; Freund, T. F.;...

compound diacylglycerol (DAG) is a precursor to the endocannabinoid 2-arachidonoylglycerol (2-AG) while fatty acid amide hydrolase (FAAH) mediates the metabolism...

"Purification and characterization of sn-1-stearoyl-2-arachidonoylglycerol kinase from pig testes". Biochem. J. 322 (Pt 2): 529–34. doi:10.1042/bj3220529. PMC 1218222...

stores since at least the early 2020s in North America and Europe. HHC has 2 diastereomers that only differ by the orientation of the 9-methyl group, unlike...

acid amide hydrolase (FAAH) can hydrolyze the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide at comparable rates in vitro, genetic or pharmacological...

"Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2-Arachidonoylglycerol in Oxazolone-Induced Contact Dermatitis in Mice". Journal of Immunology...

Devane and Lumír Ondřej Hanuš. Another endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), was discovered in 1995 by Shimon Ben-Shabat, one of his PhD...

(delta-5-tetrahydrocannabinol) delta-10-Tetrahydrocannabinol (delta-2-tetrahydrocannabinol) delta-6-Cannabidiol 11-Hydroxy-Delta-8-THC Endocannabinoid...

Drug Administration (FDA). November 2, 2017. Archived from the original on January 26, 2018. Retrieved January 2, 2018. Fox A, Ravitz JR, Leongini EM...

insulin treatment has been shown to reduce intracellular ECs, the 2-arachidonoylglycerol (2-AG) and anandamide (AEA), which correspond with insulin-sensitive...