5′-Methylthioadenosine is S-methyl derivative of the adenosine. It is an intermediate in the methylthioadenosine (MTA) cycle, also known as the methionine...
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S-methyl-5'-thioadenosine phosphorylase (MTAP) is an enzyme responsible for polyamine metabolism. In humans, it is encoded by the methylthioadenosine phosphorylase...
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metabolized to ACC[clarification needed] and 5ʹ-methylthioadenosine by ACC synthase. 5ʹ-methylthioadenosine is then recycled back into Met. Along with the...
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state structures. Methylthioadenosine nucleosidase are enzymes that catalyse the hydrolytic deadenylation reaction of 5'-methylthioadenosine and S-adenosylhomocysteine...
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universal methionine salvage pathway recycling methionine from 5'-methylthioadenosine". IUBMB Life. 61 (12): 1132–42. doi:10.1002/iub.278. PMID 19946895...
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To a lesser extent, the enzyme also catalyzes the deamination of 5′-methylthioadenosine, S-adenosylhomocysteine, and adenosine. The molecular mass of the...
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In enzymology, a methylthioadenosine nucleosidase (EC 3.2.2.16) is an enzyme that catalyzes the chemical reaction S-methyl-5'-thioadenosine + H2O ⇌ {\displaystyle...
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S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31, MTA deaminase, 5-methylthioadenosine deaminase) is an enzyme with systematic name S-methyl-5'-thioadenosine...
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phosphorylase, methylthioadenosine nucleoside phosphorylase, 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase, and S-methyl-5-thioadenosine...
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S-adenosylhomocysteine nucleosidase, 5'-methyladenosine nucleosidase, S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase, and AdoHcy/MTA nucleosidase...
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reported that about 7% of adult supplement users exceeded the UL for folate and 5% of those older than age 50 years exceeded the UL for vitamin A. The USDA...
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Sym-norspermidine synthase (redirect from EC 2.5.1.23)
+ propane-1,3-diamine ⇌ {\displaystyle \rightleftharpoons } 5'-methylthioadenosine + bis(3-aminopropyl)amine Thus, the two substrates of this enzyme...
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S-methyl-5-thio-alpha-D-ribose 1-phosphate The catabolism of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine...
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Adenosylmethionine cyclotransferase (redirect from EC 2.5.1.4)
(EC 2.5.1.4) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine ⇌ {\displaystyle \rightleftharpoons } 5'-methylthioadenosine + 2-aminobutan-4-olide...
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levels in primary rat hepatocytes by inhibiting the conversion of 5′-methylthioadenosine to SAM through the methionine salvage pathway. Cycloleucine treatment...
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TRNA-uridine aminocarboxypropyltransferase (redirect from EC 2.5.1.25)
S-adenosyl-L-methionine + tRNA uridine ⇌ {\displaystyle \rightleftharpoons } 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine Thus, the two substrates...
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1-Aminocyclopropane-1-carboxylate synthase (redirect from S-adenozil-L-metionin methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming))
aminocyclopropanecarboxylate synthase, ACC synthase, and S-adenosyl-L-methionine methylthioadenosine-lyase. This enzyme participates in propanoate metabolism. It employs...
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Isonocardicin synthase (redirect from EC 2.5.1.38)
S-adenosyl-L-methionine + nocardicin E ⇌ {\displaystyle \rightleftharpoons } 5'-methylthioadenosine + isonocardicin A Thus, the two substrates of this enzyme are...
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Discadenine synthase (redirect from EC 2.5.1.24)
N6-(Delta2-isopentenyl)-adenine ⇌ {\displaystyle \rightleftharpoons } 5'-methylthioadenosine + discadenine Thus, the two substrates of this enzyme are S-adenosyl-L-methionine...
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"Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human...
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S-ribosylhomocysteine lyase (redirect from S-(5-deoxy-D-ribos-5-yl)-L-homocysteine L-homocysteine-lyase ((4S)-4,5-dihydroxypentan-2,3-dione-forming))
S-adenosyl-L-homocysteine (SRH) and adenine by S-adenosyl-L-homocysteine/5’-methylthioadenosine nucleosidase (SAHN or MTAN, EC 3.2.2.9) (8-10). LuxS cleaves...
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thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine". Journal of Molecular Biology. 388 (2): 271–82. doi:10.1016/j.jmb...
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Masaru; Willis, Erik H.; Frincke, Lee A.; Carson, Dennis A. (1984). "5′-Methylthioadenosine is the Major Source of Adenine in Human Cells". Advances in Experimental...
24 KB (2,087 words) - 07:42, 21 October 2024
BpsA (category EC 2.5.1)
group of the substrate polyamine and a sulfur atom of the product 5ʹ-methylthioadenosine with Asp 159. The enzyme proves itself to be important to thermophiles...
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S-adenosyl-L-methionine + H2O ⇌ {\displaystyle \rightleftharpoons } L-homoserine + methylthioadenosine Thus, the two substrates of this enzyme are S-adenosyl-L-methionine...
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Acyl-homoserine-lactone synthase (redirect from Acyl-(acyl-carrier protein):S-adenozil-L-metionin acyltranserase (lactone-forming, methylthioadenosine-releasing))
protein):S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing). This enzyme catalyses the following chemical reaction...
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cogenerates methionine S-adenosyl homocysteine, releasing methyl radical methylthioadenosine (SMT), homoalanine radical The reactions that produce, consume, and...
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S-adenosylmethionine. The latter donates the equivalent of 4-aminobutyrolactone. Methylthioadenosine is a coproduct. Homoserine lactone is also a product of the proteolytic...
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Methylthioribulose 1-phosphate dehydratase (redirect from S-methyl-5-thio-D-ribulose-1-phosphate 4-hydro-lyase (5-(methylthio)-2,3-dioxopentyl-phosphate-forming))
Furfine ES, Abeles RH (1988). "Intermediates in the conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae". J. Biol. Chem. 263 (20):...
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Family 3.A.1.32 The Cobalamin Precursor (B12-P) Family 3.A.1.33 The Methylthioadenosine (MTA) Family ABC3 (InterPro: IPR003838): 3.A.1.114 The Probable Glycolipid...
111 KB (14,443 words) - 02:35, 30 October 2024