• Thumbnail for ABCA7
    cassette sub-family A member 7 is a protein that in humans is encoded by the ABCA7 gene. The protein encoded by this gene is a member of the superfamily of...
    32 KB (2,880 words) - 20:09, 26 September 2024
  • inside to the outside of cell membranes. The ABCA7 gene is among the top ten risk genes for AD. Risk from the ABCA7 gene is the strongest for African Americans...
    43 KB (4,490 words) - 12:16, 20 September 2024
  • found in ABCA7, or ATP binding cassette subfamily A member 7, have been associated with increased early-onset and late-onset AD risk. ABCA7 is an ATP-binding...
    88 KB (9,045 words) - 19:13, 21 August 2024
  • Thumbnail for Alzheimer's disease
    other genes associated with autosomal dominant Alzheimer's disease are ABCA7 and SORL1. Alleles in the TREM2 gene have been associated with a three to...
    183 KB (19,400 words) - 23:51, 23 September 2024
  • ABCA4 HGNC:34 P78363 35 ABCA5 HGNC:35 Q8WWZ7 36 ABCA6 HGNC:36 Q8N139 37 ABCA7 HGNC:37 Q8IZY2 38 ABCA8 HGNC:38 O94911 39 ABCA9 HGNC:39 Q8IUA7 40 ABCA10...
    277 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for ABC transporter
    to six different chromosomes. These are ABCA1, ABCA2, ABCA3, and ABCA4, ABCA7, ABCA12, and ABCA13. The other subgroup consists of ABCA5 and ABCA6 and...
    111 KB (14,477 words) - 12:52, 26 August 2024
  • brain. ABCA7 exhibits strong genetic linkage to AD; it is involved in lipid and cholesterol processing, as well as immune system function. ABCA7 exhibits...
    57 KB (6,147 words) - 15:28, 12 June 2024
  • Thumbnail for 2011 in science
    Paul; Harold; Sims, Rebecca; Gerrish, Amy (2011). "Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease"...
    200 KB (18,798 words) - 13:53, 13 September 2024
  • Thumbnail for Kári Stefánsson
    Stefansson and the deCODE team have also discovered variants in the TREM2 and ABCA7 genes that increase risk of AD.    Stefansson and his team have used the...
    103 KB (12,457 words) - 23:46, 12 June 2024
  • Thumbnail for ATP-binding domain of ABC transporters
    axis. ABCA1; ABCA10; ABCA12; ABCA13; ABCA2; ABCA3; ABCA4; ABCA5; ABCA6; ABCA7; ABCA8; ABCA9; ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8;...
    8 KB (752 words) - 05:06, 14 March 2022
  • Thumbnail for ABCG8
    among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and...
    9 KB (1,153 words) - 00:43, 27 February 2024
  • Thumbnail for HMHA1
    "Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene". Biochem...
    8 KB (729 words) - 07:28, 11 December 2023
  • Thumbnail for ABCD4
    among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and...
    5 KB (644 words) - 03:59, 29 January 2023
  • Thumbnail for ABCA8
    among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and...
    4 KB (507 words) - 12:55, 24 January 2024