resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of...
13 KB (1,849 words) - 08:43, 30 April 2024
receptor and H1 receptor. Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice. This drug is highly lipofilic...
8 KB (567 words) - 12:45, 5 August 2024
other HG tested (with the exception of KO1), carried allelic variants at ABCC1 gene associated with wet earwax, normal body odor and normal colostrum [69]...
19 KB (2,216 words) - 21:45, 25 June 2024
to bile by the ATP-binding cassette (ABC) transporter proteins: ABCB1, ABCC1, ABCC2, and ABCG2. Irinotecan clearance is mainly biliary (66%) and estimated...
26 KB (2,315 words) - 04:55, 13 April 2024
P-glycoprotein (P-gp/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1), and breast cancer resistance protein (BCRP/ABCG2) in cancer cells that...
111 KB (14,477 words) - 18:38, 28 June 2024
19p13.2 040 PEL PEL 13q32.1 041 MAM MAM 19q13.33 042 EMM EMM 4p16.3 043 ABCC1 ABCC1 16p13.11 044 Er Er Protein Era, Erb, Er3, Er4, and Er5 Illustrates potential...
21 KB (1,374 words) - 08:55, 11 June 2024
suggestive of selection pressures. This concerns the genes EDAR, ADH1B, ABCC1, and ALDH2 in particular. The East Asian types of ADH1B are associated with...
112 KB (11,948 words) - 20:00, 10 August 2024
P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R))". Biochemical...
3 KB (79 words) - 13:29, 2 April 2023
ABCB9 HGNC:50 Q9NP78 50 ABCB10 HGNC:41 Q9NRK6 51 ABCB11 HGNC:42 O95342 52 ABCC1 HGNC:51 P33527 53 ABCC2 HGNC:53 Q92887 54 ABCC3 HGNC:54 O15438 55 ABCC4...
277 KB (17 words) - 23:17, 27 April 2024
overcome this difficulty, the ATP-binding cassette (ABC) transporter C1 (ABCC1) serves as the "exit door" for S1P. On the other hand, the cystic fibrosis...
55 KB (5,633 words) - 08:40, 12 July 2024
resistance-associated protein 1 (ABCC1) was also found to be regulated by N1IC, which suggest a mechanism of ABCC1 regulated by presenilin 1 and notch...
25 KB (3,113 words) - 11:23, 31 December 2023
be transported by the multidrug resistance-associated protein 1 (MRP1; ABCC1). Flutamide is metabolized by CYP1A2 (via α-hydroxylation) in the liver...
99 KB (10,959 words) - 06:32, 12 May 2024
elasticum: Point mutations in the ABCC6 gene and a large deletion including also ABCC1 and MYH11". Hum. Mutat. 18 (1): 85. doi:10.1002/humu.1157. PMID 11439001...
10 KB (1,334 words) - 08:39, 29 January 2023
selection for a number of alleles, including variants of the EDAR, ADH1B, ABCC1, and ALDH2 genes. The East Asian types of ADH1B in particular are associated...
47 KB (5,247 words) - 05:06, 28 July 2024
and functional properties of human multidrug resistance protein 1 (MRP1/ABCC1)". Current Medicinal Chemistry. 18 (3): 439–81. doi:10.2174/092986711794839197...
46 KB (5,491 words) - 20:47, 14 June 2024
ABCA9; ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9;...
8 KB (752 words) - 05:06, 14 March 2022
synthase (LTC4S); LTC4 exits its cells of origin through the MRP1 transporter (ABCC1) and is rapidly converted to LTD4 and then to LTE4) by cell surface-attached...
61 KB (7,553 words) - 05:55, 27 May 2024
Ketabi-Kiyanvash N, Lindenmaier H, Haefeli WE (March 2007). "Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside...
17 KB (1,709 words) - 18:12, 10 June 2024
InterPro: IPR014342 ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC13; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8;...
4 KB (429 words) - 04:12, 7 November 2023
elasticum: Point mutations in the ABCC6 gene and a large deletion including also ABCC1 and MYH11". Hum Mutat. 18 (1): 85. doi:10.1002/humu.1157. PMID 11439001...
7 KB (919 words) - 04:29, 25 January 2024
synthase. LTC4 then exits its cells of origin through the MRP1 transporter (ABCC1) and is rapidly converted to LTD4 and then to LTE4) by cell surface-attached...
25 KB (3,101 words) - 22:04, 2 January 2024
et al 1998). The ABC transporters identified, AtMRP1 and AtMRP2 (alias AtABCC1 and AtABCC2), were shown to be involved in the ATP-energized vacuolar sequestration...
35 KB (4,379 words) - 16:37, 11 July 2024