humans is encoded by the ADAM12 gene. ADAM12 has two splice variants: ADAM12-L, the long form, has a transmembrane region and ADAM12-S, a shorter variant...

protease enzyme whose catalytic mechanism involves a metal. An example is ADAM12 which plays a significant role in the fusion of muscle cells during embryo...

Fusion in humans is aided by a set of metalloproteinases coded for by the ADAM12 gene, and a variety of other proteins. Fusion involves recruitment of actin...

HGNC:216 Q13443 254 ADAM10 HGNC:188 O14672 255 ADAM11 HGNC:189 O75078 256 ADAM12 HGNC:190 O43184 257 ADAM15 HGNC:193 Q13444 258 ADAM17 HGNC:195 P78536 259...

(2005). "Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity". Proc. Natl. Acad. Sci. U.S.A. 102 (8): 3058–63...

region of chromosome 17q21 previously defined by tumor deletion mapping. ADAM12 ADAM12, a metalloprotease that binds insulin growth factor binding protein-3...

have been implicated in the proteolytic cleavage of LRP1 such as ADAM10, ADAM12, ADAM17 and MT1-MMP. LRP1 is also continuously endocytosed from the membrane...

Satoshi Ansai, Masato Kinoshita and Atsuko Sehara-Fujisawa. 58 409-421 2016 ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage...

Alpha-actinin 2 has been shown to interact with KCNA5, DLG1, DISC1, MYOZ1, GRIN2B, ADAM12, ACTN3, MYPN, PDLIM3, PKN, MYOT, TTN, NMDAR, SYNPO2, LDB3, and FATZ. The...

IGF1R and promote cell survival. IGFBP3 has been shown to interact with: ADAM12 ADAM28 COL1A1 FN1 IGFALS IGF1, IGF2 HSPA5 Humanin PLG RXRA TF KPNB1 PRKDC...

are associated to SHORT syndrome. PIK3R1 has been shown to interact with: ADAM12, BCAR1, CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A...

PMID 12477932. Mori S, Tanaka M, Nanba D, et al. (2003). "PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal...