factor 1 is a protein that in humans is encoded by the ARF1 gene. ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family...
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GTP but poorly or not at all to the GDP nucleotide. Structural studies of Arf1 and Arf6 have revealed that although these proteins feature the switch 1...
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form symmetric trimers ("triads"). The curved triad structure positions the Arf1 molecules and cargo binding sites proximal to the membrane. The β′- and α-COP...
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necessary for the pre-coupling. It has also been shown to interact with Arf6 and ARF1. Muscarinic acetylcholine receptor GRCh38: Ensembl release 89: ENSG00000133019...
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Golgi membrane, it must interact with a small GTPase called ARF1 (ADP ribosylation factor). ARF1 that is bound to GDP interacts with the golgi complex membrane...
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downregulate response to epinephrine AGPAT1 acyl 3 phosphoglycerol acyl transferase ARF1 ARF3 ARF4 ARF5 ARL2 RAS Superfamily CSF1 Colony stimulating factor not highly...
48 KB (4,612 words) - 23:41, 12 December 2023
scission of the plasma membrane (PM) independent of dynamin, dependence on Arf1 activity, enrichment in GPI-anchored proteins, increased susceptibility to...
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PMC 341922. PMID 14742873. Ulmasov, T; Hagen, G; Guilfoyle, TJ (1997). "ARF1, a transcription factor that binds to auxin response elements". Science....
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to interact with ADP-ribosylation factor 1 (ARF1). The encoded protein likely promotes hydrolysis of ARF1-bound GTP, which is required for the dissociation...
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α-l-arabinofuranosidase called Arf1, which accounts for almost all the arabinofuranosidase activity in the cells. Arf1 is a trimer or tetramer of between...
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+2-nt movement of the toeprint of the pre-termination complex. The archaeal aRF1–EF1α–GTP complex is similar. The triggering mechanism is similar to that...
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cellular adhesion RAP1A; RAP1B; RAP2A; RAP2B; RAP2C Arf vesicular transport ARF1; ARF3; ARF4; ARF5; ARF6; ARL1; ARL2; ARL3; ARL4; ARL5; ARL5C; ARL6; ARL7;...
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originally known as 'KIAA1110', under which name it was found to act as a GEF for Arf1 but not Arf6. It is related to the other Arf-GEF protein IQSEC1. "www.genenames...
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Jackson, Catherine L. (2005-03-01). "Dynamics of GBF1, a Brefeldin A-Sensitive Arf1 Exchange Factor at the Golgi". Molecular Biology of the Cell. 16 (3): 1213–1222...
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is shown here. Exomer binds to 2 molecules of ADP-ribosylation factor 1 (Arf1) as shown in this figure. A hinge region of exomer is thought to be important...
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family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members...
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HGNC:649 P48444 915 AREG HGNC:651 P15514 916 AREL1 HGNC:20363 O15033 917 ARF1 HGNC:652 P84077 918 ARF3 HGNC:654 P61204 919 ARF4 HGNC:655 P18085 920 ARF5...
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John A G (2017-06-16). "9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments". eLife. 6. doi:10...
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Jiangsha; Yin, Weiqin; Liu, Dayong; Chen, WanJun; Hou, Steven X. (2020-01-10). "Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces...
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(via the CYFIP1 component of the complex) and Arf small GTPases (such as ARF1, ARF5, and ARF6 ) or the similar protein ARL1, which causes dissociation...
4 KB (481 words) - 19:51, 23 September 2021
which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of...
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sorting and membrane trafficking. CYTH2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. CYTH2 protein is 83% homologous to CYTH1. Two transcript...
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molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature...
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The protein encoded by this gene stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein is thought to be involved in membrane transport...
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and membrane trafficking. CYTH4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The CYTH4 and CYTH1 gene structures are...
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Chavrier P (2005). "Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics". Nat. Cell Biol. 7 (4): 353–64...
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for the uptake of cargo into transport vesicles and that the small GTPase Arf1 and COPI components play a role in mRNA transport and mRNA metabolism. Her...
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ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. GRCh38: Ensembl release 89: ENSG00000008256 – Ensembl, May 2017 GRCm38:...
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mitochondria-ER contact sites is from the Golgi apparatus. Golgi contain ARF1 proteins localized on their membranes, which are capable of recruiting kinases...
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family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members...
8 KB (1,027 words) - 14:16, 27 March 2022