Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase...

Soluble adenylyl cyclase (sAC) is a regulatory cytosolic enzyme present in almost every cell. sAC is a source of cyclic adenosine 3’,5’ monophosphate (cAMP)...

of molecular biology, the cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade...

Photoactivated adenylyl cyclase (PAC) is a protein consisting of an adenylyl cyclase enzyme domain directly linked to a BLUF (blue light receptor using...

S2CID 5739004. Waschek JA (2002). "Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration"...

reaction to form a cyclic compound. Important cyclase enzymes include: Adenylyl cyclase, which forms cyclic AMP from adenosine triphosphate (EC 4.6.1.1) ADCY1...

and stimulating cone photoreceptor death. Adenylyl cyclase Cyclic guanosine monophosphate Guanylyl cyclase activator (protein) Martin, Emil; Berka, Vladimir;...

of adenylyl cyclase and its activity. Adenylyl cyclase plays an essential role in cognition. Neurofibromin's role in the activity of adenylyl cyclase explains...

protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα...

subunit Gs-α, a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways. GNAS stands for Guanine Nucleotide binding...

study and research of cell physiology. Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second...

on the cell surface. Cyclic AMP is formed from ATP by the enzymes adenylyl cyclase. In 1970 Martin Rodbell found that hormones did not directly influence...

Adenylyl cyclase type 5 is an enzyme that in humans is encoded by the ADCY5 gene. ADCY5 has been shown to interact with RGS2. Mutations in ADCY5 are known...

dissociates from the G protein, and associates with adenylyl cyclase. This causes the inactivation of adenylyl cyclase, resulting in a decrease of cAMP produced...

separates from Gβ𝛾 and interacts with the transmembrane protein adenylyl cyclase. Adenylyl cyclase catalyzes the conversion of ATP to cAMP. cAMP binds to protein...

nucleotidyl cyclases, such that production of cAMP is catalyzed by adenylyl cyclase and production of cGMP is catalyzed by guanylyl cyclase. Adenylyl cyclase has...

G-protein gets activated, which in turn, activates the enzyme adenylyl cyclase. Adenylyl cyclase then catalyzes the conversion of ATP to cyclic AMP (cAMP)...

Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene. This gene encodes adenylyl cyclase 6, which is a membrane-associated...

Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase...

Adenylyl cyclase type 1 is an enzyme that in humans is encoded by the ADCY1 gene. This gene encodes a form of adenylyl cyclase expressed in the brain....

The cyclic AMP is generated by the oocyte by adenylyl cyclase in the oocyte membrane. The adenylyl cyclase is kept active by a constitutively active G-protein-coupled...

are inhibited with an antagonist, ethanol consumption is reduced. Adenylyl cyclase (AC) plays a role in ethanol induced signaling pathways. Acute ethanol...

Signalling via Gαs activation of adenylyl cyclase. 5-HT5A 251.2 Memory consolidation. Signals via Gi/o inhibition of adenylyl cyclase. 5-HT6 98.41 Cognition (antagonists...

receptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP)...

calcium-dependent adenylate cyclase activation, might also account for the detection of the repetitive stimulation of a given synapse. Adenylyl cyclase (also commonly...

proteins primarily inhibit the cAMP dependent pathway by inhibiting adenylyl cyclase activity, decreasing the production of cAMP from ATP, which, in turn...

IA, Lerner RA, Wigler M (1988). "Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition...

protein Gsα. D1 is also coupled to Golf. Gsα subsequently activates adenylyl cyclase, increasing the intracellular concentration of the second messenger...

preclinical or early development: Short-term inhibition of soluble adenylyl cyclase has been demonstrated to temporarily impair sperm motility and capacitation...

synergistic increase in cAMP is mediated by and dependent on rutabaga adenylyl cyclase (rut AC), which is sensitive to both calcium (which results from voltage-gated...